Planet Pharma
The Pre-Pivotal Drug Substance Technologies organization at develops, characterizes and supports clinical drug substance manufacturing processes for all early-stage programs in the portfolio.
This lab-based position is located at our Thousand Oaks, CA site. The successful candidate will be responsible for support of the development, characterization, scale-up and support of upstream and downstream processes to enable clinical advancement of programs.
This role is in an integrated bioprocess development group in which cell culture and purification scientists work together to advance rich, exciting and dynamic pipeline. With biology first approach, the position provides the unique opportunity to work on multiple modalities including antibodies, BiTEs, oncolytic viruses, bispecifics, and siRNAs.
The successful candidate will design and execute experiments at the bench scale, spanning the end-to-end drug substance process, including both cell culture and purification operations. The candidate will apply established platform approaches and utilize problem-solving skills to rapidly solve day-to-day experimental challenges. Additionally, the candidate will utilize out-of-the-box thinking to contribute to technology development, including process automation. Finally, the candidate will also expand and develop skills in both cell culture and purification, thereby further contributing to the integrated group.
Day to Day Responsibilities:
• Work in a team environment to contribute to drug substance process development. • Complete mammalian cell culture experiments at different scales in shake flasks and bioreactors. • Implement purification experiments, mainly filtration and chromatography, at bench and pilot scale as needed. • Document experimental data in lab notebooks. • Analyze the data and present to the team. • Author technical reports and support regulatory filing as needed. • Contribute to technology development projects to seek continuous improvement in reliability and efficiency. • The candidate will have opportunities to work in cell culture development and purification development to become a well-rounded process development scientist with experience in upstream and downstream.
This lab-based position is located at our Thousand Oaks, CA site. The successful candidate will be responsible for support of the development, characterization, scale-up and support of upstream and downstream processes to enable clinical advancement of programs.
This role is in an integrated bioprocess development group in which cell culture and purification scientists work together to advance rich, exciting and dynamic pipeline. With biology first approach, the position provides the unique opportunity to work on multiple modalities including antibodies, BiTEs, oncolytic viruses, bispecifics, and siRNAs.
The successful candidate will design and execute experiments at the bench scale, spanning the end-to-end drug substance process, including both cell culture and purification operations. The candidate will apply established platform approaches and utilize problem-solving skills to rapidly solve day-to-day experimental challenges. Additionally, the candidate will utilize out-of-the-box thinking to contribute to technology development, including process automation. Finally, the candidate will also expand and develop skills in both cell culture and purification, thereby further contributing to the integrated group.
Day to Day Responsibilities:
• Work in a team environment to contribute to drug substance process development. • Complete mammalian cell culture experiments at different scales in shake flasks and bioreactors. • Implement purification experiments, mainly filtration and chromatography, at bench and pilot scale as needed. • Document experimental data in lab notebooks. • Analyze the data and present to the team. • Author technical reports and support regulatory filing as needed. • Contribute to technology development projects to seek continuous improvement in reliability and efficiency. • The candidate will have opportunities to work in cell culture development and purification development to become a well-rounded process development scientist with experience in upstream and downstream.