Vertex Pharmaceuticals
Supervisor, Manufacturing Operations (2nd Shift)
Vertex Pharmaceuticals, Boston, Massachusetts, us, 02298
Supervisor, Manufacturing Operations (2nd Shift) Join to apply for the
Supervisor, Manufacturing Operations (2nd Shift)
role at
Vertex Pharmaceuticals .
You could be just the right applicant for this job Read all associated information and make sure to apply. General Summary:
The Supervisor, Manufacturing Operations leads shift work in the clinical manufacturing facility, assigning work according to detailed schedules and plans. Responsible for daily cGMP operations in the clinical manufacturing area and overseeing the daily work of shift personnel. Responsible for daily operation and staff allocations for shift personnel. Ensures schedule adherence is met daily, troubleshoots, and escalates operational variances. Shift : This is a second shift role with a schedule of Tuesday - Saturday, 1:30 PM - 10:00 PM (40 hours). Key Duties And Responsibilities
Builds and develops an efficient team of 2-8 direct reports capable of consistently producing clinical product according to cGMP standards, including hiring, orienting, training and coaching of personnel. Ensure cGMP compliance through direct oversight and education of team members. Share responsibility of scheduling personnel in coordination with other Manufacturing leadership. Manage direct reports’ projects to achieve department and corporate goals, including managing timelines and leading group meetings. Lead, investigate, and collaborate with cross-functional stakeholders regarding quality systems, including quality events, deviations, CAPAs, change controls, and risk assessments. Create, revise, and review controlled documents including Standard Operating Procedures (SOPs) and Batch Records for manufacturing. Demonstrate Vertex Phenotype behaviors: Lead by Example; Learn, Teach & Develop; Foster Exceptional Collaboration; Drive Breakthrough Results; and Promote Enterprise Thinking. Other duties and projects as assigned to meet departmental requirements. Knowledge And Skills
Ability to follow verbal and written instructions in English. Ability to lift up to 50 lbs. Strong organizational and communication skills, with excellent documentation abilities. Strong understanding of the cGMP framework in the context of both development and commercial pharmaceutical drug product manufacturing. Basic computer skills and ability to learn new systems and technologies. Experience in managing team development goals. Education And Experience
Prior GMP leadership experience, such as project or personnel leadership. At least 5 years of experience in process development and/or manufacturing of cell therapy products preferred. Experience with embryonic or induced pluripotent stem cell culture. Prior experience with scale-up processes. Previous experience with electronic quality systems. Experience collaborating with Quality Assurance and Supply Chain. Pay Range $100,800 - $151,200 Disclosure Statement The range provided is based on a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary will be based on factors including skills, competencies, experience, and other job-related factors permitted by law. Vertex Total Rewards include comprehensive benefits, paid time off, educational assistance, 401(k) matching, and more. Flex Designation On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Applicants requiring accommodation should contact the recruiter or Talent Acquisition at ApplicationAssistance@vrtx.com. Seniority level
Mid-Senior level Employment type
Full-time Job function
Management and Manufacturing
#J-18808-Ljbffr
Supervisor, Manufacturing Operations (2nd Shift)
role at
Vertex Pharmaceuticals .
You could be just the right applicant for this job Read all associated information and make sure to apply. General Summary:
The Supervisor, Manufacturing Operations leads shift work in the clinical manufacturing facility, assigning work according to detailed schedules and plans. Responsible for daily cGMP operations in the clinical manufacturing area and overseeing the daily work of shift personnel. Responsible for daily operation and staff allocations for shift personnel. Ensures schedule adherence is met daily, troubleshoots, and escalates operational variances. Shift : This is a second shift role with a schedule of Tuesday - Saturday, 1:30 PM - 10:00 PM (40 hours). Key Duties And Responsibilities
Builds and develops an efficient team of 2-8 direct reports capable of consistently producing clinical product according to cGMP standards, including hiring, orienting, training and coaching of personnel. Ensure cGMP compliance through direct oversight and education of team members. Share responsibility of scheduling personnel in coordination with other Manufacturing leadership. Manage direct reports’ projects to achieve department and corporate goals, including managing timelines and leading group meetings. Lead, investigate, and collaborate with cross-functional stakeholders regarding quality systems, including quality events, deviations, CAPAs, change controls, and risk assessments. Create, revise, and review controlled documents including Standard Operating Procedures (SOPs) and Batch Records for manufacturing. Demonstrate Vertex Phenotype behaviors: Lead by Example; Learn, Teach & Develop; Foster Exceptional Collaboration; Drive Breakthrough Results; and Promote Enterprise Thinking. Other duties and projects as assigned to meet departmental requirements. Knowledge And Skills
Ability to follow verbal and written instructions in English. Ability to lift up to 50 lbs. Strong organizational and communication skills, with excellent documentation abilities. Strong understanding of the cGMP framework in the context of both development and commercial pharmaceutical drug product manufacturing. Basic computer skills and ability to learn new systems and technologies. Experience in managing team development goals. Education And Experience
Prior GMP leadership experience, such as project or personnel leadership. At least 5 years of experience in process development and/or manufacturing of cell therapy products preferred. Experience with embryonic or induced pluripotent stem cell culture. Prior experience with scale-up processes. Previous experience with electronic quality systems. Experience collaborating with Quality Assurance and Supply Chain. Pay Range $100,800 - $151,200 Disclosure Statement The range provided is based on a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary will be based on factors including skills, competencies, experience, and other job-related factors permitted by law. Vertex Total Rewards include comprehensive benefits, paid time off, educational assistance, 401(k) matching, and more. Flex Designation On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Applicants requiring accommodation should contact the recruiter or Talent Acquisition at ApplicationAssistance@vrtx.com. Seniority level
Mid-Senior level Employment type
Full-time Job function
Management and Manufacturing
#J-18808-Ljbffr