Columbia University
Assistant Professor of Medical Sciences (in Medicine) at CUMC - Hematology &Onco
Columbia University, New York, New York, United States, 10027
Columbia University Irving Medical Center - Department of Medicine
Columbia University Irving Medical Center invites outstanding candidates to apply for positions at the rank of
Assistant Professor . These positions are based with leading research labs in
cancer immunotherapy
and
technology development
and are part of the
Columbia Center for Translational Immunology
and the
Herbert Irving Comprehensive Cancer Center .
We are seeking candidates with demonstrated excellence and future potential in the areas of
gene editing ,
cell engineering ,
cancer genomics , and
computational biology , who can lead a research program at the intersection of
basic science ,
translational research , and
clinical application . Successful candidates will demonstrate a record of significant research accomplishments and the potential to establish creative, independent research programs with a commitment to teaching and mentoring at the graduate, medical, and postdoctoral levels.
Research Focus Areas
1. Gene Editing & Cell Engineering
Development and application of advanced gene editing tools (e.g., CRISPR, base editing) in human and murine immune cells
Engineering of immune cells for therapeutic applications, including CAR-T and other cell therapies
Collaboration with the Columbia University Irving Medical Center's cell manufacturing facility for clinical translation
2. Functional Genomics & High-Throughput Screening
Massively parallel CRISPR-based perturbation screens
Functional characterization of disease-associated variants and variants enhancing therapeutic efficacy
Synthetic biology and model systems to dissect gene function in cancer and immune contexts
3. Cancer Genomics & Systems Medicine
Study of mutational processes, clonal evolution, chromosomal instability, and the tumor microenvironment
Integration of multi-omics datasets (e.g., genomics, transcriptomics, epigenomics) to uncover cancer mechanisms
4. Advanced Sequencing Technologies
Application and development of cutting-edge methods such as:
Single-cell RNA-seq and ATAC-seq
Spatial transcriptomics
Long-read sequencing
Whole-genome/exome sequencing (WGS/WES)
5. Computational Biology & AI
Development of predictive models of therapy response using machine learning/AI
Multi-modal data integration and quantitative systems biology approaches
Mathematical modeling to inform therapeutic strategies in precision oncology and immunotherapy
Columbia offers access to:
State-of-the-art core facilities for sequencing, cell engineering, and imaging
High-performance computing and data science support
Biobanking and patient-derived model systems
A rich and collaborative scientific community spanning basic, clinical, and translational domains
Applicants must hold a Ph.D. and/or M.D. (or equivalent degree) in related discipline.
Demonstrated record of significant research accomplishments and the potential to establish a creative, independent research program.
Commitment to teaching and mentoring at the graduate, medical, and postdoctoral levels.
Columbia University is an Equal Opportunity Employer / Disability / Veteran
Pay Transparency Disclosure
The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training.
The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
Columbia University Irving Medical Center invites outstanding candidates to apply for positions at the rank of
Assistant Professor . These positions are based with leading research labs in
cancer immunotherapy
and
technology development
and are part of the
Columbia Center for Translational Immunology
and the
Herbert Irving Comprehensive Cancer Center .
We are seeking candidates with demonstrated excellence and future potential in the areas of
gene editing ,
cell engineering ,
cancer genomics , and
computational biology , who can lead a research program at the intersection of
basic science ,
translational research , and
clinical application . Successful candidates will demonstrate a record of significant research accomplishments and the potential to establish creative, independent research programs with a commitment to teaching and mentoring at the graduate, medical, and postdoctoral levels.
Research Focus Areas
1. Gene Editing & Cell Engineering
Development and application of advanced gene editing tools (e.g., CRISPR, base editing) in human and murine immune cells
Engineering of immune cells for therapeutic applications, including CAR-T and other cell therapies
Collaboration with the Columbia University Irving Medical Center's cell manufacturing facility for clinical translation
2. Functional Genomics & High-Throughput Screening
Massively parallel CRISPR-based perturbation screens
Functional characterization of disease-associated variants and variants enhancing therapeutic efficacy
Synthetic biology and model systems to dissect gene function in cancer and immune contexts
3. Cancer Genomics & Systems Medicine
Study of mutational processes, clonal evolution, chromosomal instability, and the tumor microenvironment
Integration of multi-omics datasets (e.g., genomics, transcriptomics, epigenomics) to uncover cancer mechanisms
4. Advanced Sequencing Technologies
Application and development of cutting-edge methods such as:
Single-cell RNA-seq and ATAC-seq
Spatial transcriptomics
Long-read sequencing
Whole-genome/exome sequencing (WGS/WES)
5. Computational Biology & AI
Development of predictive models of therapy response using machine learning/AI
Multi-modal data integration and quantitative systems biology approaches
Mathematical modeling to inform therapeutic strategies in precision oncology and immunotherapy
Columbia offers access to:
State-of-the-art core facilities for sequencing, cell engineering, and imaging
High-performance computing and data science support
Biobanking and patient-derived model systems
A rich and collaborative scientific community spanning basic, clinical, and translational domains
Applicants must hold a Ph.D. and/or M.D. (or equivalent degree) in related discipline.
Demonstrated record of significant research accomplishments and the potential to establish a creative, independent research program.
Commitment to teaching and mentoring at the graduate, medical, and postdoctoral levels.
Columbia University is an Equal Opportunity Employer / Disability / Veteran
Pay Transparency Disclosure
The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training.
The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.