Senior Medical Director of Clinical Development

The Organization Entrada Therapeutics is a dynamic clinical-stage biopharmaceutical company focused onenhancing the lives of patients through groundbreaking medicines. Our unique Endosomal Escape Vehicle (EEV)-therapeutics empower efficient intracellular delivery of a wide array of treatments targeting various organs and tissues, aiming for an improved therapeutic index. We are advancing a diverse portfolio of RNA- and protein-based programs, particularly for neuromuscular and ocular diseases. Our leading oligonucleotide initiatives target potential treatments for Duchenne muscular dystrophy and we have partnered to develop VX-670 for myotonic dystrophy type 1. Our dedicated team comprises experts in therapeutic development and rare diseases, and we are excited to expand our collaborative group of professionals committed to making a real difference for patients and their families. Your Role As the Senior Medical Director, you will report to the Senior Vice President of Clinical Development and play a pivotal role in advancing neuromuscular development programs through all stages of clinical trials. Your ability to build strategic relationships with external stakeholders and provide clinical insight will be key to our success. Key Responsibilities Lead and oversee clinical programs, ensuring the planning, execution, and completion of clinical trials meet regulatory standards and company protocols. Work closely with internal research teams to integrate findings into clinical strategies. Collaborate with Clinical Operations to uphold compliance with all applicable regulations and guidelines. Review clinical data and assist in generating reports and publications. Establish and maintain key relationships with opinion leaders and Principal Investigators. Act as a representative for Entrada in discussions with regulatory agencies. Provide regular updates to management regarding progress and potential changes to projects. Ensure adherence to regulatory standards in global clinical trials and physician interactions. Cultivate professional relationships with academic and community-based study sites. Lead team members and external partners in developing regulatory submission materials. Be responsible for the content of clinical and regulatory documents, including protocols and INDs. Organize and present at clinical advisory boards and scientific meetings. Travel nationally and internationally as needed. What We Seek MD/DO or equivalent required. 3+ years of experience in clinical research or industry, particularly in Neurology/Neuromuscular disorders. Strong scientific foundation and project management skills. Expertise in clinical trial management from inception to completion. Ability to communicate complex information clearly to diverse audiences. Knowledge of FDA and ICH regulations, along with Good Clinical Practice (GCP). Strong attention to detail and ability to multitask. Proven capability to foster cross-functional relationships and proactive problem-solving. This role is remote, with preference for candidates based in New England. Quarterly travel to our headquarters in Boston, MA is required. What We Offer At Entrada Therapeutics, we value transparency and equity in compensation. We offer a competitive salary ranging from $328,000 - $387,000, depending on qualifications and experience. Our comprehensive benefits package includes health, dental, and vision coverage, life insurance, 401(k) matching, paid parental leave, education reimbursement, and more. Our Boston office is located in a vibrant area, providing an engaging work environment. Join us in making impactful contributions; we look forward to welcoming you to our team!