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Overview
Senior Scientist, Potency Assay Location: San Diego, CA Employment Type: Full-time Hiring Company: BioPhase (on behalf of our client) Pay: $145,000–$165,000 base + bonus; stock options Hours: Monday–Friday, full-time Apply today and join our team! Responsibilities
Build GMP QC-compatible target engagement and cell-based potency assays for multiple modalities. Culture/maintain cell lines and create well-documented cell banks for assay use. Identify, qualify, and manage critical reagents; maintain assay readiness. Author/review development reports, method transfer/verification/qualification protocols, and summaries. Review GMP release/stability results; support OOS/OOT investigations, QC data review, and batch release at partner sites. Partner with CDMOs on reference standard qualification and assay lifecycle management. Collaborate cross-functionally to advance programs from discovery to CMC. Qualifications
MS/PhD in Biology, Biochemistry, or related field. 5+ years’ industry experience developing potency assays. Hands-on expertise qualifying recombinant and cell-based assays (target binding, signaling, cytotoxicity) for GMP use. Proficient with data analysis tools (e.g., GraphPad Prism, SoftMax Pro). Strong communicator; effective with internal teams and external CDMOs. Prior CDMO collaboration and exposure to regulatory filings. Experience with process-related impurity testing (bioburden, HCP, residual DNA, leached Protein A). Benefits
Comprehensive package including medical, dental, vision, life & insurance; 401(k); FSA; EAP; PTO & parental leave; flexible schedule; relocation assistance; year-end shutdown.
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Senior Scientist, Potency Assay Location: San Diego, CA Employment Type: Full-time Hiring Company: BioPhase (on behalf of our client) Pay: $145,000–$165,000 base + bonus; stock options Hours: Monday–Friday, full-time Apply today and join our team! Responsibilities
Build GMP QC-compatible target engagement and cell-based potency assays for multiple modalities. Culture/maintain cell lines and create well-documented cell banks for assay use. Identify, qualify, and manage critical reagents; maintain assay readiness. Author/review development reports, method transfer/verification/qualification protocols, and summaries. Review GMP release/stability results; support OOS/OOT investigations, QC data review, and batch release at partner sites. Partner with CDMOs on reference standard qualification and assay lifecycle management. Collaborate cross-functionally to advance programs from discovery to CMC. Qualifications
MS/PhD in Biology, Biochemistry, or related field. 5+ years’ industry experience developing potency assays. Hands-on expertise qualifying recombinant and cell-based assays (target binding, signaling, cytotoxicity) for GMP use. Proficient with data analysis tools (e.g., GraphPad Prism, SoftMax Pro). Strong communicator; effective with internal teams and external CDMOs. Prior CDMO collaboration and exposure to regulatory filings. Experience with process-related impurity testing (bioburden, HCP, residual DNA, leached Protein A). Benefits
Comprehensive package including medical, dental, vision, life & insurance; 401(k); FSA; EAP; PTO & parental leave; flexible schedule; relocation assistance; year-end shutdown.
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