EyeBio
Overview
Translational Medicine at our Research Division is responsible for early clinical development of novel therapeutics, working in close collaboration with Discovery Sciences and late-stage Clinical Research. We work with all therapeutic areas within our Research Division. We are seeking a highly qualified individual for a position in our group. Candidates must have a strong background in basic and/or clinical translational research and a desire to work collaboratively across different therapeutic areas. Responsibilities
Contribute to the identification of novel targets by partnering with discovery research teams to bring a clinical perspective into the earliest stages of target identification and validation, and execute clinical studies to evaluate the relevance of potential targets to human disease to justify investment in full development that can be bridged into full development Develop biomarker strategies through cross-functional teams that provide line-of-sight from First-in-Human studies through clinical Proof-of-Concept; this includes experimental medicine studies to establish and/or validate biomarker platforms Lead the early clinical development strategy for novel therapy programs from Preclinical Candidate approval through Clinical Pharmacology testing (Phase 1) and clinical Proof-of-Concept (Phase 2) Develop and execute clinical pharmacology strategies to support later stages of development from Proof-of-Concept (Phase 2) through worldwide marketing application Collaborate within Translational Medicine and with Discovery Sciences and late-stage Clinical Research to ensure integrity, knowledge, imagination, creativity, skill, diversity and teamwork in the group Principal responsibilities
Key member of an early development team, providing leadership in designing and executing early clinical development strategy Development and execution of early clinical strategy for novel therapeutics including authoring initial clinical and biomarker plans for Lead Optimization programs, early clinical development plans for Preclinical Candidate molecules, and clinical pharmacology studies for programs in Phases I through IV Development and execution of studies to validate clinical platforms utilizing established and novel biomarkers, including imaging, electrophysiological and behavioral responses to interrogate biological activity in humans Provide clinical expertise for identification and validation of novel targets, including design of preclinical and/or clinical pharmacology experiments to validate targets and/or pathways Safe and timely execution of Phase I studies; collaborate with internal and external clinical study support staff and scientists (including discovery research, biostatistics, drug metabolism, modeling and simulation, regulatory affairs, and global clinical trials operations) Provide clinical pharmacology support for programs through worldwide marketing application filing including supportive registration documents and presentations Provide clear, timely communication and interpretation of study results to therapeutic area governance, functional area experts and development review committees Contribute to assessment of internal and external opportunities identified by Business Development and Licensing Interface broadly with key functions including Discovery Sciences, Preclinical Pharmacology, Pharmaceutical Sciences, Toxicology, Translational Biomarkers, Translational Medicine Operations, Drug Metabolism/Modeling & Simulation, Regulatory Affairs, and late-stage Clinical Research across research sites around the world Education
MD/PhD or MD Required qualifications
Proven track record in clinical medicine or clinical research and background in biomedical research Demonstrated record of scientific scholarship and achievement; the particular clinical or scientific background is less important than a track record of excellence and collaboration across therapeutic areas Strong interpersonal, writing and presentation skills and ability to function in a team environment Clinical Board Certification preferred Prior specific experience in clinical research and prior publication preferably with experience in basic or translational research and experience with early clinical development and patient care Additional information
Current Employees apply in the usual process. Current Contingent Workers apply in the usual process. US and Puerto Rico Residents Only: We are committed to inclusion and providing accommodations during the application process. Equal Employment Opportunity: We provide equal opportunities to all employees and applicants and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics. For more information about personal rights under U.S. Equal Opportunity Employment laws, visit the EEOC Know Your Rights resources. We are proud to be a company that embraces diversity and inclusion. The fastest path to breakthrough innovation is through diverse ideas and collaboration. Other
Hybrid work model applies to certain positions as described in company policy; some roles require on-site work. Salary range for this role is 255,200.00 - 401,700.00. The successful candidate will be eligible for annual bonuses and long-term incentives where applicable. Benefits include medical, dental, vision, retirement plans and paid holidays/vacations. Compensation and benefits details are provided in the official offer and policy documents.
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Translational Medicine at our Research Division is responsible for early clinical development of novel therapeutics, working in close collaboration with Discovery Sciences and late-stage Clinical Research. We work with all therapeutic areas within our Research Division. We are seeking a highly qualified individual for a position in our group. Candidates must have a strong background in basic and/or clinical translational research and a desire to work collaboratively across different therapeutic areas. Responsibilities
Contribute to the identification of novel targets by partnering with discovery research teams to bring a clinical perspective into the earliest stages of target identification and validation, and execute clinical studies to evaluate the relevance of potential targets to human disease to justify investment in full development that can be bridged into full development Develop biomarker strategies through cross-functional teams that provide line-of-sight from First-in-Human studies through clinical Proof-of-Concept; this includes experimental medicine studies to establish and/or validate biomarker platforms Lead the early clinical development strategy for novel therapy programs from Preclinical Candidate approval through Clinical Pharmacology testing (Phase 1) and clinical Proof-of-Concept (Phase 2) Develop and execute clinical pharmacology strategies to support later stages of development from Proof-of-Concept (Phase 2) through worldwide marketing application Collaborate within Translational Medicine and with Discovery Sciences and late-stage Clinical Research to ensure integrity, knowledge, imagination, creativity, skill, diversity and teamwork in the group Principal responsibilities
Key member of an early development team, providing leadership in designing and executing early clinical development strategy Development and execution of early clinical strategy for novel therapeutics including authoring initial clinical and biomarker plans for Lead Optimization programs, early clinical development plans for Preclinical Candidate molecules, and clinical pharmacology studies for programs in Phases I through IV Development and execution of studies to validate clinical platforms utilizing established and novel biomarkers, including imaging, electrophysiological and behavioral responses to interrogate biological activity in humans Provide clinical expertise for identification and validation of novel targets, including design of preclinical and/or clinical pharmacology experiments to validate targets and/or pathways Safe and timely execution of Phase I studies; collaborate with internal and external clinical study support staff and scientists (including discovery research, biostatistics, drug metabolism, modeling and simulation, regulatory affairs, and global clinical trials operations) Provide clinical pharmacology support for programs through worldwide marketing application filing including supportive registration documents and presentations Provide clear, timely communication and interpretation of study results to therapeutic area governance, functional area experts and development review committees Contribute to assessment of internal and external opportunities identified by Business Development and Licensing Interface broadly with key functions including Discovery Sciences, Preclinical Pharmacology, Pharmaceutical Sciences, Toxicology, Translational Biomarkers, Translational Medicine Operations, Drug Metabolism/Modeling & Simulation, Regulatory Affairs, and late-stage Clinical Research across research sites around the world Education
MD/PhD or MD Required qualifications
Proven track record in clinical medicine or clinical research and background in biomedical research Demonstrated record of scientific scholarship and achievement; the particular clinical or scientific background is less important than a track record of excellence and collaboration across therapeutic areas Strong interpersonal, writing and presentation skills and ability to function in a team environment Clinical Board Certification preferred Prior specific experience in clinical research and prior publication preferably with experience in basic or translational research and experience with early clinical development and patient care Additional information
Current Employees apply in the usual process. Current Contingent Workers apply in the usual process. US and Puerto Rico Residents Only: We are committed to inclusion and providing accommodations during the application process. Equal Employment Opportunity: We provide equal opportunities to all employees and applicants and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics. For more information about personal rights under U.S. Equal Opportunity Employment laws, visit the EEOC Know Your Rights resources. We are proud to be a company that embraces diversity and inclusion. The fastest path to breakthrough innovation is through diverse ideas and collaboration. Other
Hybrid work model applies to certain positions as described in company policy; some roles require on-site work. Salary range for this role is 255,200.00 - 401,700.00. The successful candidate will be eligible for annual bonuses and long-term incentives where applicable. Benefits include medical, dental, vision, retirement plans and paid holidays/vacations. Compensation and benefits details are provided in the official offer and policy documents.
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