ZipRecruiter
Senior Scientist in Single-Cell Assay Development
ZipRecruiter, Pleasanton, California, United States, 94566
Were looking for a Senior Scientist in Single-Cell Assay Development to help pioneer and validate novel approaches to scalable single-cell analysis. Youll be instrumental in designing, optimizing, and validating robust single-cell workflowsfrom concept to product. As an early team member, you'll shape both the scientific direction and the culture of the R&D team, helping establish a lean, high-performing, and high-output environment.
Key Responsibilities
Lead the development of novel single-cell assays (e.g., scRNAseq, scDNAseq, multi-omic) tailored to CS Genetics proprietary platform.
Design and execute experiments for assay optimization, troubleshooting, and validation using DOE and data-driven approaches.
Collaborate across teams (Molecular Biology, Automation, Computational Biology) to integrate chemistry, workflow, and software into unified products.
Establish best practices in lab execution, documentation, and data integrity to ensure reproducibility and quality.
Build scalable protocols and documentation to support eventual tech transfer to manufacturing.
Help shape team culture, workflows, and scientific strategy in a startup environment that values autonomy, speed, and rigor.
Mentor junior scientists and contribute to recruiting efforts as the team grows.
Qualifications
PhD in Molecular Biology, Analytical Chemistry, Biochemistry, or related field (or MS + 5+ years of hands-on experience).
37 years of industry or advanced academic experience developing single-cell genomics assays.
Deep understanding of molecular biology principals and practice, nucleic acid chemistry, and NGS workflows.
Strong bench skills in molecular biology (e.g., RT, ligation, tagmentation, amplification).
Experience with assay optimization using DOE/statistical design.
Familiarity with lab automation and high-throughput sample handling.
Experience culturing mammalian cells
Comfortable working in a fast-paced, evolving startup; capable of switching between high-level strategy and hands-on execution.
Strong communication and organizational skills; commitment to quality and innovation.
Experience with basic processing and analysis of single cell data is a plus
What We Offer
A chance to build something truly transformative from the ground up.
High ownership and autonomy in a fast-moving environment.
Opportunities to shape company direction and culture.
Competitive salary, equity, and benefits.
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Key Responsibilities
Lead the development of novel single-cell assays (e.g., scRNAseq, scDNAseq, multi-omic) tailored to CS Genetics proprietary platform.
Design and execute experiments for assay optimization, troubleshooting, and validation using DOE and data-driven approaches.
Collaborate across teams (Molecular Biology, Automation, Computational Biology) to integrate chemistry, workflow, and software into unified products.
Establish best practices in lab execution, documentation, and data integrity to ensure reproducibility and quality.
Build scalable protocols and documentation to support eventual tech transfer to manufacturing.
Help shape team culture, workflows, and scientific strategy in a startup environment that values autonomy, speed, and rigor.
Mentor junior scientists and contribute to recruiting efforts as the team grows.
Qualifications
PhD in Molecular Biology, Analytical Chemistry, Biochemistry, or related field (or MS + 5+ years of hands-on experience).
37 years of industry or advanced academic experience developing single-cell genomics assays.
Deep understanding of molecular biology principals and practice, nucleic acid chemistry, and NGS workflows.
Strong bench skills in molecular biology (e.g., RT, ligation, tagmentation, amplification).
Experience with assay optimization using DOE/statistical design.
Familiarity with lab automation and high-throughput sample handling.
Experience culturing mammalian cells
Comfortable working in a fast-paced, evolving startup; capable of switching between high-level strategy and hands-on execution.
Strong communication and organizational skills; commitment to quality and innovation.
Experience with basic processing and analysis of single cell data is a plus
What We Offer
A chance to build something truly transformative from the ground up.
High ownership and autonomy in a fast-moving environment.
Opportunities to shape company direction and culture.
Competitive salary, equity, and benefits.
#J-18808-Ljbffr