Arrowhead Pharmaceuticals
Director Medical Value, Evidence, and Outcomes
Arrowhead Pharmaceuticals, Pasadena, California, United States, 91122
Overview
Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company focused on developing medicines that silence disease-causing genes using RNA interference (RNAi). Arrowhead has a pipeline in liver and lung targets, with research and development teams in Madison, WI and San Diego, CA, and a manufacturing facility in Verona, WI. The Director of Medical Value, Evidence, and Outcomes (MVEO) will play a pivotal role in the launch of Arrowhead’s investigational cardiometabolic molecule – Plozasiran (siRNA targeting APOC3). The MVEO Director will be a key member of the Medical Affairs Leadership Team, reporting to the Vice President of Medical Affairs. This is a multifaceted role with two main focus areas: designing, implementing, managing, and disseminating Medical Real World Evidence (RWE); and partnering with Market Access to engage payers with medically focused presentations. Cross-functional collaboration includes Regulatory, Clinical Development, Biometrics, and Commercial teams. This role is based in Pasadena, California, with an expectation to be in office 5 days a week. Responsibilities
Develop and execute the Real World Evidence (RWE) generation strategy for Arrowhead’s cardiometabolic pipeline to inform value propositions from both medical and payer perspectives. Develop and review economic resources, including cost-effectiveness models, to support value propositions. Integrate research findings into payer communication materials. Develop publications and external communications based on real world evidence generation, partnering closely with the publications lead. Educate payers by delivering impactful scientific and economic data presentations. Collaborate with commercial team members to align payer positioning and messaging with outcome-based evidence; share expertise as a trusted partner. Effectively manage consultants and vendors. Review clinical development plans, including trial design, endpoints, and analytical strategies, to provide feedback and ensure alignment with payer needs. Attend medical, pharmacy, and payer professional meetings to stay current on industry trends and research affecting Familial Chylomicronemia Syndrome (FCS), Severe Hypertriglyceridemia (SHTG), and Mixed Hyperlipidemia. Conduct horizon scanning and maintain literature awareness to identify scientific gaps and opportunities in the cardiometabolic space. Stay informed about current advancements and developments in RNA interference. Qualifications
Advanced degree in health economics, health outcomes research, or a related field (MSc, MPH, PhD, PharmD, MD). At least five years of relevant experience in health economics, outcomes research, pricing, reimbursement, medical affairs, and/or portfolio analysis. Experience in the cardiometabolic therapeutic area, preferably with a focus on dyslipidemias. Ability to clearly communicate complex scientific and medical concepts, both written and oral; detail-oriented and data-driven. Ensure compliance with corporate policies, procedures, and US healthcare laws and regulations. Ability to work collaboratively in a matrixed, team-based environment, with strong organizational and time management capabilities. Exceptional project management skills, ensuring on-time and budget-compliant deliverables. Comfortable working in a fast-paced, team-based environment. California pay range: $210,000—$240,000 USD. Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US. California Applicant Privacy Policy.
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Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company focused on developing medicines that silence disease-causing genes using RNA interference (RNAi). Arrowhead has a pipeline in liver and lung targets, with research and development teams in Madison, WI and San Diego, CA, and a manufacturing facility in Verona, WI. The Director of Medical Value, Evidence, and Outcomes (MVEO) will play a pivotal role in the launch of Arrowhead’s investigational cardiometabolic molecule – Plozasiran (siRNA targeting APOC3). The MVEO Director will be a key member of the Medical Affairs Leadership Team, reporting to the Vice President of Medical Affairs. This is a multifaceted role with two main focus areas: designing, implementing, managing, and disseminating Medical Real World Evidence (RWE); and partnering with Market Access to engage payers with medically focused presentations. Cross-functional collaboration includes Regulatory, Clinical Development, Biometrics, and Commercial teams. This role is based in Pasadena, California, with an expectation to be in office 5 days a week. Responsibilities
Develop and execute the Real World Evidence (RWE) generation strategy for Arrowhead’s cardiometabolic pipeline to inform value propositions from both medical and payer perspectives. Develop and review economic resources, including cost-effectiveness models, to support value propositions. Integrate research findings into payer communication materials. Develop publications and external communications based on real world evidence generation, partnering closely with the publications lead. Educate payers by delivering impactful scientific and economic data presentations. Collaborate with commercial team members to align payer positioning and messaging with outcome-based evidence; share expertise as a trusted partner. Effectively manage consultants and vendors. Review clinical development plans, including trial design, endpoints, and analytical strategies, to provide feedback and ensure alignment with payer needs. Attend medical, pharmacy, and payer professional meetings to stay current on industry trends and research affecting Familial Chylomicronemia Syndrome (FCS), Severe Hypertriglyceridemia (SHTG), and Mixed Hyperlipidemia. Conduct horizon scanning and maintain literature awareness to identify scientific gaps and opportunities in the cardiometabolic space. Stay informed about current advancements and developments in RNA interference. Qualifications
Advanced degree in health economics, health outcomes research, or a related field (MSc, MPH, PhD, PharmD, MD). At least five years of relevant experience in health economics, outcomes research, pricing, reimbursement, medical affairs, and/or portfolio analysis. Experience in the cardiometabolic therapeutic area, preferably with a focus on dyslipidemias. Ability to clearly communicate complex scientific and medical concepts, both written and oral; detail-oriented and data-driven. Ensure compliance with corporate policies, procedures, and US healthcare laws and regulations. Ability to work collaboratively in a matrixed, team-based environment, with strong organizational and time management capabilities. Exceptional project management skills, ensuring on-time and budget-compliant deliverables. Comfortable working in a fast-paced, team-based environment. California pay range: $210,000—$240,000 USD. Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US. California Applicant Privacy Policy.
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