Generate Biomedicines, Inc.
Vice President, Global Respiratory Products Leader Somerville, MA/Andover, MA
Generate Biomedicines, Inc., Andover, Massachusetts, us, 05544
Working together toward
limitless possibilities.
We are differentiated in the composition of our team, which includes individuals from all areas— science, technology, and business —who share apioneering mindset, and are passionate about finding better ways to create medicines for patients.
We seek diverse perspectives because we believe that engaging in candid, productive conflict around ideas is how we will push the boundaries of
the possible . Vice President, Global Respiratory Products Leader
About Generate:Biomedicines Generate:Biomedicines is a new kind of therapeutics company – existing at the intersection of machine learning, biological engineering, and medicine – pioneering Generative Biology to create breakthrough medicines where novel therapeutics are computationally generated, instead of being discovered. The Company has built a machine learning-powered biomedicines platform with the potential to generate new drugs across a wide range of biologic modalities. This platform represents a potentially fundamental shift in what is possible in the field of biotherapeutic development. We pursue this audacious vision because we believe in the unique and revolutionary power of generative biology to radically transform the lives of billions, with an outsized opportunity for patients in need. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us! Generate:Biomedicines was founded in 2018 by Flagship Pioneering and has received nearly $700 millionin funding, providing the resources to rapidly scale the organization. The Company has offices in Somerville and Andover, Massachusetts with 300+ employees. The Role: Generate:Biomedicines is seeking an experienced and strategic cross-functional team leader accountable for designing and delivering our late-stage respiratory programs, including asthma and COPD. Reporting directly to the Chief Medical Officer, this is a senior level business leader who will recruit and develop a team of physicians and scientists with accountability for the global clinical trials, collaborating with PV to ensure rigorous safety oversight, data integrity, and strategic alignment. The ideal candidate is an MD with significant industry experience in respiratory medicine and a track record of driving executional excellence in pivotal trials. Here's how you will contribute: Leads a high performing Respiratory Product Strategy Team (RPST) comprised of cross-functional leaders accountable for setting the strategy for the late stage respiratory programs Direct management and development of medical monitors and clinical scientists Develops high quality, ambitious development plans for asthma and COPD programs, aligned with late-stage and corporate objectives and compliant with all relevant regulations Recruits, mentors and manages late-state clinicians and scientists Collaborates with Head of Safety and PV to define risk-benefit profiles Collaborates with Clinical operations and CRO to deliver study to timelines and budget Oversees protocol development and clinical/scientific content for regulatory submissions and interactions Provides medical leadership and awareness of evolving external landscape for late-stage clinical trials in respiratory diseases (asthma, COPD) Drives development and refinement of Target Product Profiles (TPPs), Target Product Claims,and clinical development strategies Oversee protocol development, study design, medical review of data, and safety monitoring Serve as the primary medical contact for clinical sites, investigators, and regulatory bodies Guide interactions with external stakeholders including KOLs, advisory boards, and CROs Represent Generate externally at scientific, medical, and regulatory meetings Leadership Responsibilities Hold teams to high standards for technical and collaborative performance Build and develop a diverse, high-performing, and inclusive team culture Promote enterprise thinking and cross-functional alignment with strategic goals Communicate with clarity, courage, and empathy across all levels of the organization Foster resilience, adaptability, and informed risk-taking in pursuit of innovation The Ideal Candidate will have: MD (required), board certification in Pulmonology or Allergy and Immunology Medicine preferred 10+ years of clinical development experience in the biopharma industry Deep expertise in respiratory diseases (asthma, COPD) and late-stage clinical trials Demonstrated success in leading pivotal global studies and regulatory interactions Strong analytical, communication, and cross-functional leadership skills Proven ability to influence internal and external stakeholders, including investigators and health authorities Education: MD required; additional scientific training (e.g., fellowship, MPH) a plus Nice to Have (Optional): Previous work in both large pharma and biotech settings Knowledge of global regulatory requirements (e.g., FDA, EMA) Recent successful BLA submission preferred Location:
This role will be based out of our headquarters in Somerville, MA or secondary location, Andover, MA. Why Join Us This is a unique opportunity to shape the future of respiratory medicine at a company pioneering Generative Biology. You’ll be empowered to lead transformative trials in a collaborative, mission-driven environment, surrounded by relentless problem solvers who are reimagining what’s possible in drug discovery and development. Generate:Biomedicines is committed to equal employment opportunity
regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Recruitment & Staffing Agencies
: Generate:Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate:Biomedicines and the Company will not owe any referral or other fees with respect thereto. Compensation:
The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package. Per Year Salary Range $281,000 - $422,000 USD Create a Job Alert Interested in building your career at Generate Biomedicines? Get future opportunities sent straight to your email. Accepted file types: pdf, doc, docx, txt, rtf Enter manually Accepted file types: pdf, doc, docx, txt, rtf Education School Select... Degree * Select... Address Line 1 * Street address Address Line 2 street address continued City * The city in which you reside State * Select... The State within the United States in which you reside Postal Code * Are you legally authorized to work in the United States? * Do you now or will you in the future require sponsorship to work in the U.S.? (e.g., H-1B, O-1, OPT, etc)? * Select... If you'll require the company to commence ("sponsor") an immigration or work permit case in order to employ you, either now or at some point in the future, then you should select Yes. Otherwise, select No. Are you able to work in the specified job location, or are you willing to relocate for this position? * Select... Do you hold an MD (Medical Degree) or international equivalent? * Select... How would you rate your degree of expertise in respiratory diseases (e.g. asthma, COPD, etc)? * Select... When are you able to start a new position? * How did you hear about this job? * Select... If other, please share source LinkedIn Profile Website What geographical area do you live in? * Select... Demographic Questions
At Generate Biomedicines, we value belonging and believe in fostering an environment where a diversity of perspectives can thrive. This core value is a pillar of our business and critical to our success. Your responses will be used (in aggregate only) to help us identifyareas of improvement in our process. Your responses will not be associated with your specific application and will not
in any way be used in the hiring decision. Completion of the form is entirely voluntary . How would you describe yourself as male, female, and/or transgender? (Select all that apply) Select... Which of the following best represents how you think of yourself? (Select all that apply) Select... How would you describe your race? (Select all that apply) Select... Are you of Hispanic, Latino, or Spanish origin? Select... Have you served on active duty in the U.S. Armed Forces, Reserves, or National Guard? Select...
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limitless possibilities.
We are differentiated in the composition of our team, which includes individuals from all areas— science, technology, and business —who share apioneering mindset, and are passionate about finding better ways to create medicines for patients.
We seek diverse perspectives because we believe that engaging in candid, productive conflict around ideas is how we will push the boundaries of
the possible . Vice President, Global Respiratory Products Leader
About Generate:Biomedicines Generate:Biomedicines is a new kind of therapeutics company – existing at the intersection of machine learning, biological engineering, and medicine – pioneering Generative Biology to create breakthrough medicines where novel therapeutics are computationally generated, instead of being discovered. The Company has built a machine learning-powered biomedicines platform with the potential to generate new drugs across a wide range of biologic modalities. This platform represents a potentially fundamental shift in what is possible in the field of biotherapeutic development. We pursue this audacious vision because we believe in the unique and revolutionary power of generative biology to radically transform the lives of billions, with an outsized opportunity for patients in need. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us! Generate:Biomedicines was founded in 2018 by Flagship Pioneering and has received nearly $700 millionin funding, providing the resources to rapidly scale the organization. The Company has offices in Somerville and Andover, Massachusetts with 300+ employees. The Role: Generate:Biomedicines is seeking an experienced and strategic cross-functional team leader accountable for designing and delivering our late-stage respiratory programs, including asthma and COPD. Reporting directly to the Chief Medical Officer, this is a senior level business leader who will recruit and develop a team of physicians and scientists with accountability for the global clinical trials, collaborating with PV to ensure rigorous safety oversight, data integrity, and strategic alignment. The ideal candidate is an MD with significant industry experience in respiratory medicine and a track record of driving executional excellence in pivotal trials. Here's how you will contribute: Leads a high performing Respiratory Product Strategy Team (RPST) comprised of cross-functional leaders accountable for setting the strategy for the late stage respiratory programs Direct management and development of medical monitors and clinical scientists Develops high quality, ambitious development plans for asthma and COPD programs, aligned with late-stage and corporate objectives and compliant with all relevant regulations Recruits, mentors and manages late-state clinicians and scientists Collaborates with Head of Safety and PV to define risk-benefit profiles Collaborates with Clinical operations and CRO to deliver study to timelines and budget Oversees protocol development and clinical/scientific content for regulatory submissions and interactions Provides medical leadership and awareness of evolving external landscape for late-stage clinical trials in respiratory diseases (asthma, COPD) Drives development and refinement of Target Product Profiles (TPPs), Target Product Claims,and clinical development strategies Oversee protocol development, study design, medical review of data, and safety monitoring Serve as the primary medical contact for clinical sites, investigators, and regulatory bodies Guide interactions with external stakeholders including KOLs, advisory boards, and CROs Represent Generate externally at scientific, medical, and regulatory meetings Leadership Responsibilities Hold teams to high standards for technical and collaborative performance Build and develop a diverse, high-performing, and inclusive team culture Promote enterprise thinking and cross-functional alignment with strategic goals Communicate with clarity, courage, and empathy across all levels of the organization Foster resilience, adaptability, and informed risk-taking in pursuit of innovation The Ideal Candidate will have: MD (required), board certification in Pulmonology or Allergy and Immunology Medicine preferred 10+ years of clinical development experience in the biopharma industry Deep expertise in respiratory diseases (asthma, COPD) and late-stage clinical trials Demonstrated success in leading pivotal global studies and regulatory interactions Strong analytical, communication, and cross-functional leadership skills Proven ability to influence internal and external stakeholders, including investigators and health authorities Education: MD required; additional scientific training (e.g., fellowship, MPH) a plus Nice to Have (Optional): Previous work in both large pharma and biotech settings Knowledge of global regulatory requirements (e.g., FDA, EMA) Recent successful BLA submission preferred Location:
This role will be based out of our headquarters in Somerville, MA or secondary location, Andover, MA. Why Join Us This is a unique opportunity to shape the future of respiratory medicine at a company pioneering Generative Biology. You’ll be empowered to lead transformative trials in a collaborative, mission-driven environment, surrounded by relentless problem solvers who are reimagining what’s possible in drug discovery and development. Generate:Biomedicines is committed to equal employment opportunity
regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Recruitment & Staffing Agencies
: Generate:Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate:Biomedicines and the Company will not owe any referral or other fees with respect thereto. Compensation:
The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package. Per Year Salary Range $281,000 - $422,000 USD Create a Job Alert Interested in building your career at Generate Biomedicines? Get future opportunities sent straight to your email. Accepted file types: pdf, doc, docx, txt, rtf Enter manually Accepted file types: pdf, doc, docx, txt, rtf Education School Select... Degree * Select... Address Line 1 * Street address Address Line 2 street address continued City * The city in which you reside State * Select... The State within the United States in which you reside Postal Code * Are you legally authorized to work in the United States? * Do you now or will you in the future require sponsorship to work in the U.S.? (e.g., H-1B, O-1, OPT, etc)? * Select... If you'll require the company to commence ("sponsor") an immigration or work permit case in order to employ you, either now or at some point in the future, then you should select Yes. Otherwise, select No. Are you able to work in the specified job location, or are you willing to relocate for this position? * Select... Do you hold an MD (Medical Degree) or international equivalent? * Select... How would you rate your degree of expertise in respiratory diseases (e.g. asthma, COPD, etc)? * Select... When are you able to start a new position? * How did you hear about this job? * Select... If other, please share source LinkedIn Profile Website What geographical area do you live in? * Select... Demographic Questions
At Generate Biomedicines, we value belonging and believe in fostering an environment where a diversity of perspectives can thrive. This core value is a pillar of our business and critical to our success. Your responses will be used (in aggregate only) to help us identifyareas of improvement in our process. Your responses will not be associated with your specific application and will not
in any way be used in the hiring decision. Completion of the form is entirely voluntary . How would you describe yourself as male, female, and/or transgender? (Select all that apply) Select... Which of the following best represents how you think of yourself? (Select all that apply) Select... How would you describe your race? (Select all that apply) Select... Are you of Hispanic, Latino, or Spanish origin? Select... Have you served on active duty in the U.S. Armed Forces, Reserves, or National Guard? Select...
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