Atrium
Process Development Senior Engineering Scientific Associate
Atrium, Boston, Massachusetts, us, 02298
Process Development Senior Engineering Scientific Associate
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Process Development Senior Engineering Scientific Associate
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Atrium . General Summary:
Vertex seeks a highly skilled individual to join our Process Development team as a temporary worker. In this pivotal role, you will spearhead the late-phase process development/engineering activities for drug substance processes for one of our crucial cell and gene therapy assets. As a research associate, you will play a significant part in our internal process development work, optimizing cell-based bioreactor processes to enhance robustness, decrease aseptic risk, increase yields, and reduce the cost of goods. Your contributions may extend to process characterization and technology transfer of manufacturing processes. Based in our Boston, MA, facilities, this position offers a unique opportunity to substantially impact Vertex's mission to bring innovative therapies to patients. Project Description and Responsibilities:
Pluripotent stem cell culture and differentiation support process development. The researcher conducts experiments, documents results, and contributes to team discussions. The researcher utilizes cell biology techniques and statistical principles to support process improvement. The researcher works with bioreactors, spinners, and T-flasks to pass and expand stem cells. Key Responsibilities: Execute experiments to develop robust manufacturing processes for cell therapy products and implement them to support clinical development programs. Manage and execute pluripotent stem cell culture and differentiation to support process development, optimization, and characterization. Manage troubleshooting with a high degree of complexity. Document experimental procedures and results according to established guidelines. Perform statistical analysis of experimental data to determine critical process parameter ranges. Collaborate effectively within departmental teams and contribute to deliverables in a cross-functional environment. Ability to run and design an experiment related to cell therapy with the goal of process improvement: cell passaging and expansion in 2D (adhesion) and 3D (suspension). Coordinate resources and set priorities for own team, contributing to the department's overall goals. Requirements: BS in Biochemistry, Engineering, Biology, or related discipline with 5+ years of industry experience; an MS with 1+ years of industry experience. Able to independently execute, analyze, and document cell culture processes for biologics and cell therapy products. Experience working with cell processing devices and bioreactors. Working knowledge of GMP requirements. Excellent verbal and written communication skills and ability to handle multiple tasks while meeting timelines and adapting to changing priorities. Strong organizational skills and high attention to detail. Contract details:
12 month contract with a chance to extend. Weekend work to support cell culture activities will be required. Pay and schedule:
Pay Range $38.00/hr - $42.00/hr. Shift/Hours: Monday - Friday. Weekend work will be required. Other notices:
This job posting is for a temporary role with a third-party agency partner on assignment at Vertex Pharmaceuticals. The individual selected for this role will be offered the role as an employee of a third-party agency partner; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency partner upon offer. The actual pay rate will be based on skills, competencies, experience, location and other job-related factors permitted by law. By applying for this position, you agree to Atrium Terms and Conditions and authorize Atrium to share your application materials with Vertex. Atrium Alerts may be sent by email, phone, or text message. Your personal information will be stored in Atrium and Vertex databases. To opt out of text messaging or modify preferences, contact privacyadministrator at Atrium. No C2C or Third-Party Vendors Seniority level
Associate Employment type
Contract Job function
Science Pharmaceutical Manufacturing
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Join to apply for the
Process Development Senior Engineering Scientific Associate
role at
Atrium . General Summary:
Vertex seeks a highly skilled individual to join our Process Development team as a temporary worker. In this pivotal role, you will spearhead the late-phase process development/engineering activities for drug substance processes for one of our crucial cell and gene therapy assets. As a research associate, you will play a significant part in our internal process development work, optimizing cell-based bioreactor processes to enhance robustness, decrease aseptic risk, increase yields, and reduce the cost of goods. Your contributions may extend to process characterization and technology transfer of manufacturing processes. Based in our Boston, MA, facilities, this position offers a unique opportunity to substantially impact Vertex's mission to bring innovative therapies to patients. Project Description and Responsibilities:
Pluripotent stem cell culture and differentiation support process development. The researcher conducts experiments, documents results, and contributes to team discussions. The researcher utilizes cell biology techniques and statistical principles to support process improvement. The researcher works with bioreactors, spinners, and T-flasks to pass and expand stem cells. Key Responsibilities: Execute experiments to develop robust manufacturing processes for cell therapy products and implement them to support clinical development programs. Manage and execute pluripotent stem cell culture and differentiation to support process development, optimization, and characterization. Manage troubleshooting with a high degree of complexity. Document experimental procedures and results according to established guidelines. Perform statistical analysis of experimental data to determine critical process parameter ranges. Collaborate effectively within departmental teams and contribute to deliverables in a cross-functional environment. Ability to run and design an experiment related to cell therapy with the goal of process improvement: cell passaging and expansion in 2D (adhesion) and 3D (suspension). Coordinate resources and set priorities for own team, contributing to the department's overall goals. Requirements: BS in Biochemistry, Engineering, Biology, or related discipline with 5+ years of industry experience; an MS with 1+ years of industry experience. Able to independently execute, analyze, and document cell culture processes for biologics and cell therapy products. Experience working with cell processing devices and bioreactors. Working knowledge of GMP requirements. Excellent verbal and written communication skills and ability to handle multiple tasks while meeting timelines and adapting to changing priorities. Strong organizational skills and high attention to detail. Contract details:
12 month contract with a chance to extend. Weekend work to support cell culture activities will be required. Pay and schedule:
Pay Range $38.00/hr - $42.00/hr. Shift/Hours: Monday - Friday. Weekend work will be required. Other notices:
This job posting is for a temporary role with a third-party agency partner on assignment at Vertex Pharmaceuticals. The individual selected for this role will be offered the role as an employee of a third-party agency partner; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency partner upon offer. The actual pay rate will be based on skills, competencies, experience, location and other job-related factors permitted by law. By applying for this position, you agree to Atrium Terms and Conditions and authorize Atrium to share your application materials with Vertex. Atrium Alerts may be sent by email, phone, or text message. Your personal information will be stored in Atrium and Vertex databases. To opt out of text messaging or modify preferences, contact privacyadministrator at Atrium. No C2C or Third-Party Vendors Seniority level
Associate Employment type
Contract Job function
Science Pharmaceutical Manufacturing
#J-18808-Ljbffr