Vor Bio
Overview
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Director, Biostatistician
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Vor Bio . At Vor, we are tackling autoimmune disease at its root. We are advancing telitacicept, a dual BAFF/APRIL inhibitor, and we seek a Director, Biostatistician to lead modern trial and analysis methods in collaboration with clinical trial teams and the Early Development – Advanced Quantitative Sciences team. As part of Vor, you will contribute to a mission to redefine the future of autoimmune care and drive statistical leadership across global clinical development programs. Responsibilities
Provide strategic leadership as Vor’s global area expert in statistical methods, data science, programming, and data management. Contribute biostatistical input to clinical development strategies, protocol design, SAPs, and regulatory interactions including briefing books and submissions. Plan, monitor, and analyze global clinical studies; coordinate statistical aspects of regulatory submissions. Manage and oversee vendors (CROs, IRT, eCOA, etc.) and ensure quality statistical deliverables. Collaborate with cross-functional teams (global medical, clinical operations, regulatory, safety) to ensure efficient trial execution. Oversee execution of global statistical analyses and the preparation of statistical methods and results for clinical study reports and data interpretation. Support medical teams and external expert committees with dataset programming for global study data review and safety monitoring. Provide guidance on data collection, trial design, and analysis for global studies across various data streams (CRF, eCOA, and other platforms). Lead blinded and unblinded IDMC activities from strategy to generation of TLFs. Maintain up-to-date statistical methods, industry standards, regulatory requirements, and related guidance for global clinical development. Prepare clinical study modules for eCTD, review and prepare CDISC-compliant IWRS specs, ADaM specs, and related documentation. Support molecule development and publication strategies by providing statistical thinking and interpretation of results. Requirements
Position Summary:
The Director, Biostatistician will lead implementation of modern and innovative trial designs, statistical models, and analysis methods at the study or project level, collaborating with the clinical trial teams and other quantitative partners in the Early Development – Advanced Quantitative Sciences team. Education: Master’s degree in Biostatistics, Statistics, or related field required. Ph.D. in related field, preferred. Experience: At least 10 years' experience responsible for biostatistics of clinical trials. Experience collaborating with scientific teams to design robust experiments and clinical trials. Demonstrated experience applying statistical theories and methods to solve complex biological problems. Experience using statistical software such as R, SAS, or SPSS for data analysis and modeling. Familiarity with complex statistical methods applicable to clinical trials. Skills: Strong analytical thinking and problem-solving abilities. Ability to handle multiple projects simultaneously. Excellent written and verbal communication skills. Ability to work cross-functionally in a fast-paced, collaborative environment. Strong attention to detail. At Vor, we offer robust benefits and an inclusive work environment. Vor Bio is an equal opportunity employer; all applicants will be considered regardless of race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. Please visit our website at https://www.vorbio.com/ for more information. Job Details
Seniority level: Director Employment type: Full-time Job function: Research, Analyst, and Information Technology Location: Boston, MA or related locations We encourage you to apply if you are excited about contributing to autoimmune disease research and the advancement of statistical science in clinical development.
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Join to apply for the
Director, Biostatistician
role at
Vor Bio . At Vor, we are tackling autoimmune disease at its root. We are advancing telitacicept, a dual BAFF/APRIL inhibitor, and we seek a Director, Biostatistician to lead modern trial and analysis methods in collaboration with clinical trial teams and the Early Development – Advanced Quantitative Sciences team. As part of Vor, you will contribute to a mission to redefine the future of autoimmune care and drive statistical leadership across global clinical development programs. Responsibilities
Provide strategic leadership as Vor’s global area expert in statistical methods, data science, programming, and data management. Contribute biostatistical input to clinical development strategies, protocol design, SAPs, and regulatory interactions including briefing books and submissions. Plan, monitor, and analyze global clinical studies; coordinate statistical aspects of regulatory submissions. Manage and oversee vendors (CROs, IRT, eCOA, etc.) and ensure quality statistical deliverables. Collaborate with cross-functional teams (global medical, clinical operations, regulatory, safety) to ensure efficient trial execution. Oversee execution of global statistical analyses and the preparation of statistical methods and results for clinical study reports and data interpretation. Support medical teams and external expert committees with dataset programming for global study data review and safety monitoring. Provide guidance on data collection, trial design, and analysis for global studies across various data streams (CRF, eCOA, and other platforms). Lead blinded and unblinded IDMC activities from strategy to generation of TLFs. Maintain up-to-date statistical methods, industry standards, regulatory requirements, and related guidance for global clinical development. Prepare clinical study modules for eCTD, review and prepare CDISC-compliant IWRS specs, ADaM specs, and related documentation. Support molecule development and publication strategies by providing statistical thinking and interpretation of results. Requirements
Position Summary:
The Director, Biostatistician will lead implementation of modern and innovative trial designs, statistical models, and analysis methods at the study or project level, collaborating with the clinical trial teams and other quantitative partners in the Early Development – Advanced Quantitative Sciences team. Education: Master’s degree in Biostatistics, Statistics, or related field required. Ph.D. in related field, preferred. Experience: At least 10 years' experience responsible for biostatistics of clinical trials. Experience collaborating with scientific teams to design robust experiments and clinical trials. Demonstrated experience applying statistical theories and methods to solve complex biological problems. Experience using statistical software such as R, SAS, or SPSS for data analysis and modeling. Familiarity with complex statistical methods applicable to clinical trials. Skills: Strong analytical thinking and problem-solving abilities. Ability to handle multiple projects simultaneously. Excellent written and verbal communication skills. Ability to work cross-functionally in a fast-paced, collaborative environment. Strong attention to detail. At Vor, we offer robust benefits and an inclusive work environment. Vor Bio is an equal opportunity employer; all applicants will be considered regardless of race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. Please visit our website at https://www.vorbio.com/ for more information. Job Details
Seniority level: Director Employment type: Full-time Job function: Research, Analyst, and Information Technology Location: Boston, MA or related locations We encourage you to apply if you are excited about contributing to autoimmune disease research and the advancement of statistical science in clinical development.
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