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Barrington James

Associate Director Clinical Operations

Barrington James, San Francisco, California, United States, 94199

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Overview

Job Title:

Associate Director, Clinical Operations Location:

Hybrid – San Francisco, CA (2–3 days on-site) Employment Type:

Full-Time Permanent About Us Our client is a growing biotech company dedicated to developing innovative therapies that address unmet medical needs. With a recent milestone achievement in their pipeline, they are entering an exciting phase of growth and are seeking passionate and driven professionals to join the team. The culture is agile, collaborative, and science-driven, and we’re looking for leaders who are ready to make a meaningful impact. Position Summary

We are seeking an experienced

Associate Director of Clinical Operations

to lead and manage the execution of clinical trials across multiple phases. This is a

hybrid role , offering the flexibility of remote work with regular in-office collaboration. The ideal candidate will bring a deep understanding of clinical trial operations in a biotech or small/mid-sized pharma environment and be comfortable operating in a hands-on, fast-paced setting. Key Responsibilities

Oversee end-to-end execution of clinical trials, from study start-up through close-out, ensuring compliance with GCP, ICH guidelines, and regulatory requirements. Manage CROs, vendors, and internal stakeholders to ensure timelines, quality, and budget goals are met. Collaborate with cross-functional teams including Clinical Development, Regulatory Affairs, Medical Affairs, and Quality to support clinical strategy and trial design. Contribute to protocol development, site selection, monitoring plans, and clinical study reports. Lead or contribute to the development of SOPs, workflows, and operational best practices. Support inspection readiness activities and contribute to submissions and regulatory interactions. Mentor junior Clinical Operations team members and support departmental growth as the company scales. Qualifications

Bachelor’s degree in life sciences or related field; advanced degree (MS, PhD, PharmD) preferred. 8+ years of clinical operations experience, with at least 2–3 years in a leadership or management role. Prior experience in a small biotech or startup environment is highly preferred. Demonstrated success in managing global clinical trials and working with CROs and vendors. Strong understanding of clinical trial regulations, GCP/ICH guidelines, and industry best practices. Excellent communication, leadership, and organizational skills. Ability to work independently and adapt to shifting priorities in a dynamic environment. To Apply

Please submit your resume and a brief cover letter outlining your experience and interest in the role to

cburns@barringtonjames.com

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