Natera
Overview
Lead Security Architect at Natera. We are building a forward-looking cybersecurity team and seek a highly skilled, business- and technology-savvy Lead Security Architect to design and implement secure, scalable architectures across cloud, containerized, and on-premises environments. You will shape our security strategy for modern platforms across AWS, networks, OT, and SaaS platforms, develop Security Reference Architectures, and ensure alignment with enterprise security standards. Hands-on experience with security automation and proficiency in Python or a comparable scripting language are required to drive operational efficiency and consistency. Position Summary
(duplicate removed for clarity) This role supports secure integration of SaaS platforms such as Google Workspace and Salesforce and requires collaboration with cross-functional teams to embed security across the technology stack. Primary Responsibilities
Lead the development and implementation of enterprise-wide security architecture strategies and frameworks Develop and maintain threat models and security reference architectures for AWS and on-premises environments, with emphasis on Zero Trust, IAM, encryption, secure access controls, SIEM, and XDR Partner with Engineering, DevOps, IT, and Compliance to ensure secure system design and security-by-default principles Collaborate with DevOps and engineering teams to embed security into CI/CD workflows and Infrastructure-as-Code (IaC) Establish and enforce security best practices in containerized environments (e.g., EKS, ECS) and AI-enabled applications, including workload protection, runtime monitoring, and secrets management Support secure design, development, and deployment of AI/ML solutions and data pipelines with robust controls around model access, training data, and infrastructure Champion security automation and playbooks using tools such as Python, Lambda, Terraform to streamline security testing, threat detection, and remediation workflows Evaluate and recommend security tools, platforms, and automation approaches aligned with business goals and security requirements Perform architectural risk assessments and provide actionable guidance and mitigation strategies Work with Incident Response to ensure security architecture aligns with evolving threat landscapes Participate in design reviews, threat modeling exercises, and architecture governance Influence security policies and standards to align with industry best practices and regulatory frameworks (e.g., HIPAA, NIST, CISA, FDA) Stay current on industry trends and AI-driven threats to enhance the organization’s security posture Serve as a trusted technical and strategic advisor to executive leadership on security architecture and risk mitigation Mentor security engineers and developers on secure design principles and architectural best practices Qualifications
Bachelor’s degree in Computer Science, Information Security, Engineering, or related field required Master’s degree in Computer Science, Information Security, or related discipline strongly preferred Minimum of 12 years of progressive cybersecurity experience, including at least 5 years in a security architecture or senior-level engineering role Deep experience with threat modeling, design, PoC, and implementing large-scale enterprise solutions (healthcare or financial sectors preferred) Proven ability to design and implement security controls aligned with HIPAA, NIST, and CIS compliance Extensive hands-on experience in AWS cloud security and network security with Zero Trust and data protection Strong understanding of enterprise IAM systems and data protection (Okta, SailPoint, VDI, AD) Expert experience with SIEM, XDR, and cloud-native threat detection tools Expert experience in web application security, OWASP, API security, and secure design/testing Hands-on security automation experience; proficient in Python, Lambda, Terraform, or similar IaC tools Industry certifications preferred: CISSP, CCSP, AWS Certified Security – Specialty, AWS Certified Solutions Architect – Professional, or AWS Certified Advanced Networking – Specialty (or equivalent) Knowledge, Skills, And Abilities
Excellent written and verbal communication skills; able to translate complex security concepts for technical and non-technical audiences Ability to influence stakeholders and drive alignment across multiple teams Strategic thinker with a passion for security innovation and scalable defenses The pay range is listed and actual compensation is based on a wide array of factors including skill set, experience, certifications, and location. This may differ in other locations due to cost of labor considerations. Remote USA. Salary range:
$172,400—$215,450 USD Our Opportunity
Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our goal is to make personalized genetic testing part of standard care and to enable earlier and targeted interventions that improve outcomes. What We Offer: Competitive benefits including medical, dental, vision, life and disability plans; fertility care benefits; pregnancy and baby bonding leave; 401k; commuter benefits; and more. We also offer an employee referral program. For more information, visit www.natera.com. Natera is an Equal Opportunity Employer. We are committed to a diverse and inclusive workplace. All qualified applicants will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability, or any other legally protected status. California residents: see notice of data collection for California residents (link provided in description). All communications will come from an @natera.com domain. Natera does not request interviews via text messages and will not ask for personal information until a recruiter engages with you. For more information on job scams, see BBB and FBI resources.
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Lead Security Architect at Natera. We are building a forward-looking cybersecurity team and seek a highly skilled, business- and technology-savvy Lead Security Architect to design and implement secure, scalable architectures across cloud, containerized, and on-premises environments. You will shape our security strategy for modern platforms across AWS, networks, OT, and SaaS platforms, develop Security Reference Architectures, and ensure alignment with enterprise security standards. Hands-on experience with security automation and proficiency in Python or a comparable scripting language are required to drive operational efficiency and consistency. Position Summary
(duplicate removed for clarity) This role supports secure integration of SaaS platforms such as Google Workspace and Salesforce and requires collaboration with cross-functional teams to embed security across the technology stack. Primary Responsibilities
Lead the development and implementation of enterprise-wide security architecture strategies and frameworks Develop and maintain threat models and security reference architectures for AWS and on-premises environments, with emphasis on Zero Trust, IAM, encryption, secure access controls, SIEM, and XDR Partner with Engineering, DevOps, IT, and Compliance to ensure secure system design and security-by-default principles Collaborate with DevOps and engineering teams to embed security into CI/CD workflows and Infrastructure-as-Code (IaC) Establish and enforce security best practices in containerized environments (e.g., EKS, ECS) and AI-enabled applications, including workload protection, runtime monitoring, and secrets management Support secure design, development, and deployment of AI/ML solutions and data pipelines with robust controls around model access, training data, and infrastructure Champion security automation and playbooks using tools such as Python, Lambda, Terraform to streamline security testing, threat detection, and remediation workflows Evaluate and recommend security tools, platforms, and automation approaches aligned with business goals and security requirements Perform architectural risk assessments and provide actionable guidance and mitigation strategies Work with Incident Response to ensure security architecture aligns with evolving threat landscapes Participate in design reviews, threat modeling exercises, and architecture governance Influence security policies and standards to align with industry best practices and regulatory frameworks (e.g., HIPAA, NIST, CISA, FDA) Stay current on industry trends and AI-driven threats to enhance the organization’s security posture Serve as a trusted technical and strategic advisor to executive leadership on security architecture and risk mitigation Mentor security engineers and developers on secure design principles and architectural best practices Qualifications
Bachelor’s degree in Computer Science, Information Security, Engineering, or related field required Master’s degree in Computer Science, Information Security, or related discipline strongly preferred Minimum of 12 years of progressive cybersecurity experience, including at least 5 years in a security architecture or senior-level engineering role Deep experience with threat modeling, design, PoC, and implementing large-scale enterprise solutions (healthcare or financial sectors preferred) Proven ability to design and implement security controls aligned with HIPAA, NIST, and CIS compliance Extensive hands-on experience in AWS cloud security and network security with Zero Trust and data protection Strong understanding of enterprise IAM systems and data protection (Okta, SailPoint, VDI, AD) Expert experience with SIEM, XDR, and cloud-native threat detection tools Expert experience in web application security, OWASP, API security, and secure design/testing Hands-on security automation experience; proficient in Python, Lambda, Terraform, or similar IaC tools Industry certifications preferred: CISSP, CCSP, AWS Certified Security – Specialty, AWS Certified Solutions Architect – Professional, or AWS Certified Advanced Networking – Specialty (or equivalent) Knowledge, Skills, And Abilities
Excellent written and verbal communication skills; able to translate complex security concepts for technical and non-technical audiences Ability to influence stakeholders and drive alignment across multiple teams Strategic thinker with a passion for security innovation and scalable defenses The pay range is listed and actual compensation is based on a wide array of factors including skill set, experience, certifications, and location. This may differ in other locations due to cost of labor considerations. Remote USA. Salary range:
$172,400—$215,450 USD Our Opportunity
Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our goal is to make personalized genetic testing part of standard care and to enable earlier and targeted interventions that improve outcomes. What We Offer: Competitive benefits including medical, dental, vision, life and disability plans; fertility care benefits; pregnancy and baby bonding leave; 401k; commuter benefits; and more. We also offer an employee referral program. For more information, visit www.natera.com. Natera is an Equal Opportunity Employer. We are committed to a diverse and inclusive workplace. All qualified applicants will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability, or any other legally protected status. California residents: see notice of data collection for California residents (link provided in description). All communications will come from an @natera.com domain. Natera does not request interviews via text messages and will not ask for personal information until a recruiter engages with you. For more information on job scams, see BBB and FBI resources.
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