Legend Biotech US
Overview
Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across autologous and allogeneic platforms, including CAR-T, TCR-T, and NK cell-based immunotherapies. Our three R&D sites apply these technologies to pursue safe, efficacious therapeutics for patients worldwide. Legend Biotech has a global collaboration with Janssen to jointly develop and commercialize cil ta-cel for multiple myeloma. Role : Legend Biotech is seeking
Director of Operations
as part of the
Technical Operations
team based in
Raritan, NJ . Responsibilities
Oversee cell therapy production and ensure safe and compliant manufacturing operations according to cGMP requirements. Lead a ~250+ organization responsible for either non-sterile or sterile manufacturing processes in a 24/7 operation, and assign personnel to execute daily production schedules. Direct 3–6 direct reports ranging from Associate Director, Senior Manager, and Manager, with accountability for hiring, development, and performance management in a growing operation. Oversee multiple work centers to ensure high quality and compliant product supply, and manage production metrics including employee engagement, safe behavior, quality (right first time), schedule adherence, and productivity improvements. Support manufacturing investigations, change controls, and maintain inspection readiness; actively support regulatory inspections. Lead facility operating review meetings and sponsor departmental projects to drive continuous improvements and efficiencies in cell therapy Technical Operations. Support organizational design updates, operations ramp-up for commercial and clinical capacity, and collaborate with Manufacturing, Supply Chain, Engineering, MS&T, and Quality to ensure seamless execution of production schedules. Provide cross-functional leadership to ensure robust production, testing, and release of product to patients; serve as the delegate for the Head of Operations as needed and establish strong stakeholder relationships. Qualifications
Bachelor’s degree in Engineering, Life Sciences, or a related field (required). Advanced degree (MS, MBA, or PhD) preferred. Minimally 12+ years of combined experience in commercial scale cGMP manufacturing, operations management, tech transfer, process and equipment validation, or quality management; preference for Cell/Gene Therapy experience. Minimum of 5 years of progressive leadership roles in a cGMP operation; prior Biologics and/or cell therapy operations experience preferred. Experience leading large multi-level teams; track record of developing high-performing teams and succession planning. Strong communication skills and ability to interact with all organizational levels; effective collaboration across cross-functional groups. Experience in a growth environment managing fast-paced change and planning horizon improvements. Proven experience leading audits and inspections (FDA, EMA, etc.). Ability to build strong partnerships with internal and external collaborators in a matrixed environment; strong prioritization and multi-tasking capabilities. Knowledge of GMP compliance and regulatory requirements; expertise in Lean Manufacturing, Six Sigma, and continuous improvement; strategic planning and budget/resource management. Technical proficiency with manufacturing systems (MES, ERP) and digital transformation initiatives. Compensation and Benefits
The anticipated base pay range is
$187,989 - $246,735 USD . Legend Biotech offers a comprehensive benefits package designed to support well-being, financial stability, and long-term career growth. Highlights include medical, dental, and vision insurance; 401(k) with company match; equity and stock options for eligible roles; paid parental leave; vacation, personal, and sick days; holidays; flexible spending and health savings accounts; life, disability, and other supplemental plans; commuter benefits; and well-being programs. EEO and Employment At-Will
Legend Biotech is an equal opportunity/affirmative action employer. Employment is at-will and may be terminated at any time by either party. Legend maintains a drug-free workplace. All applicants are considered without regard to race, color, religion, sex, national origin, disability, or any other protected status.
#J-18808-Ljbffr
Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across autologous and allogeneic platforms, including CAR-T, TCR-T, and NK cell-based immunotherapies. Our three R&D sites apply these technologies to pursue safe, efficacious therapeutics for patients worldwide. Legend Biotech has a global collaboration with Janssen to jointly develop and commercialize cil ta-cel for multiple myeloma. Role : Legend Biotech is seeking
Director of Operations
as part of the
Technical Operations
team based in
Raritan, NJ . Responsibilities
Oversee cell therapy production and ensure safe and compliant manufacturing operations according to cGMP requirements. Lead a ~250+ organization responsible for either non-sterile or sterile manufacturing processes in a 24/7 operation, and assign personnel to execute daily production schedules. Direct 3–6 direct reports ranging from Associate Director, Senior Manager, and Manager, with accountability for hiring, development, and performance management in a growing operation. Oversee multiple work centers to ensure high quality and compliant product supply, and manage production metrics including employee engagement, safe behavior, quality (right first time), schedule adherence, and productivity improvements. Support manufacturing investigations, change controls, and maintain inspection readiness; actively support regulatory inspections. Lead facility operating review meetings and sponsor departmental projects to drive continuous improvements and efficiencies in cell therapy Technical Operations. Support organizational design updates, operations ramp-up for commercial and clinical capacity, and collaborate with Manufacturing, Supply Chain, Engineering, MS&T, and Quality to ensure seamless execution of production schedules. Provide cross-functional leadership to ensure robust production, testing, and release of product to patients; serve as the delegate for the Head of Operations as needed and establish strong stakeholder relationships. Qualifications
Bachelor’s degree in Engineering, Life Sciences, or a related field (required). Advanced degree (MS, MBA, or PhD) preferred. Minimally 12+ years of combined experience in commercial scale cGMP manufacturing, operations management, tech transfer, process and equipment validation, or quality management; preference for Cell/Gene Therapy experience. Minimum of 5 years of progressive leadership roles in a cGMP operation; prior Biologics and/or cell therapy operations experience preferred. Experience leading large multi-level teams; track record of developing high-performing teams and succession planning. Strong communication skills and ability to interact with all organizational levels; effective collaboration across cross-functional groups. Experience in a growth environment managing fast-paced change and planning horizon improvements. Proven experience leading audits and inspections (FDA, EMA, etc.). Ability to build strong partnerships with internal and external collaborators in a matrixed environment; strong prioritization and multi-tasking capabilities. Knowledge of GMP compliance and regulatory requirements; expertise in Lean Manufacturing, Six Sigma, and continuous improvement; strategic planning and budget/resource management. Technical proficiency with manufacturing systems (MES, ERP) and digital transformation initiatives. Compensation and Benefits
The anticipated base pay range is
$187,989 - $246,735 USD . Legend Biotech offers a comprehensive benefits package designed to support well-being, financial stability, and long-term career growth. Highlights include medical, dental, and vision insurance; 401(k) with company match; equity and stock options for eligible roles; paid parental leave; vacation, personal, and sick days; holidays; flexible spending and health savings accounts; life, disability, and other supplemental plans; commuter benefits; and well-being programs. EEO and Employment At-Will
Legend Biotech is an equal opportunity/affirmative action employer. Employment is at-will and may be terminated at any time by either party. Legend maintains a drug-free workplace. All applicants are considered without regard to race, color, religion, sex, national origin, disability, or any other protected status.
#J-18808-Ljbffr