SanegeneBio Inc.
Summary:
Perform pioneering medicinal chemistry to design innovative RNAi technologies. This role focuses on ligand conjugation and receptor-mediated delivery to cells and tissues of high interest for drug development. Key Responsibilities Include:
Design, plan and execute siRNA conjugation and purification with a variety of ligands. Ligands are based on small molecules, peptides and antibodies.
Maintain a high level of productivity in the lab delivering on team goals, with the focus on delivering siRNA conjugates in a timely manner to meet aggressive timelines. Have teamwork spirit in following and formulating chemistry lab protocols, such as E-notebook policy, HPLC, and LC-MS. Develop medicinal chemistry and molecular design expertise, to become the next generation of scientific leaders at Sanegene. ctively participate in project meetings and present research and proposals.
Qualifications for Scientist:
A Ph.D. in synthetic organic chemistry, or oligonucleotide chemistry, with 1-2 years post-doctorate experience preferred. Experience in conjugation chemistry is desired, and antibody conjugation or purification experience is a plus. Ability to solve challenging synthetic chemistry problems in creative and effective ways, with a good track record of innovation achievements. Expert knowledge of techniques related to purification and characterization of organic compounds. Current with chemistry literature and contemporary working knowledge of emerging synthetic methodologies and technologies. Excellent verbal and written communication skills with a demonstrated ability to work collaboratively and thrive in a team environment. Excellent attention to detail, organization, presentation, and documentation skills. Skilled user of office technology such as MS office, Zoom, MS Teams etc., Fluency in Chemoffice, Scifinder and ELN.
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Perform pioneering medicinal chemistry to design innovative RNAi technologies. This role focuses on ligand conjugation and receptor-mediated delivery to cells and tissues of high interest for drug development. Key Responsibilities Include:
Design, plan and execute siRNA conjugation and purification with a variety of ligands. Ligands are based on small molecules, peptides and antibodies.
Maintain a high level of productivity in the lab delivering on team goals, with the focus on delivering siRNA conjugates in a timely manner to meet aggressive timelines. Have teamwork spirit in following and formulating chemistry lab protocols, such as E-notebook policy, HPLC, and LC-MS. Develop medicinal chemistry and molecular design expertise, to become the next generation of scientific leaders at Sanegene. ctively participate in project meetings and present research and proposals.
Qualifications for Scientist:
A Ph.D. in synthetic organic chemistry, or oligonucleotide chemistry, with 1-2 years post-doctorate experience preferred. Experience in conjugation chemistry is desired, and antibody conjugation or purification experience is a plus. Ability to solve challenging synthetic chemistry problems in creative and effective ways, with a good track record of innovation achievements. Expert knowledge of techniques related to purification and characterization of organic compounds. Current with chemistry literature and contemporary working knowledge of emerging synthetic methodologies and technologies. Excellent verbal and written communication skills with a demonstrated ability to work collaboratively and thrive in a team environment. Excellent attention to detail, organization, presentation, and documentation skills. Skilled user of office technology such as MS office, Zoom, MS Teams etc., Fluency in Chemoffice, Scifinder and ELN.
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