Bristol Myers Squibb
Associate Scientist, Gene Delivery and Editing Process Development
Bristol Myers Squibb, Seattle, Washington, us, 98127
Overview
Associate Scientist, Gene Delivery and Editing Process Development Responsibilities
Perform hands-on experimental work in the development and optimization of upstream (cell culture and transfection conditions) and downstream (clarification, chromatography, tangential and normal flow filtration) unit operations for viral vector production. Support process and technology development for viral vector manufacturing platforms utilizing suspension cell culture, transient transfection, purification, and single-use systems. Support development of high-throughput process development tools such as automated multi-parallel bioreactor system (Ambr) and liquid handlers (e.g., Tecan). Design, plan, execute, and analyze lab experiments using statistical design of experiment (DOE) principles. Manage and analyze large data sets. Maintain proper documentation of experimental results using an electronic lab notebook. Summarize and present scientific data; communicate progress to project teams. Author technical documents including protocols and internal development reports. Maintain a safe work environment in accordance with policies/procedures/regulations. Education
M.S. or B.S. in Biological or Chemical Engineering, Virology, Molecular or Cellular Biology, Biochemistry, or related discipline Qualifications
0-2 years of hands-on experience with biological process unit operations and equipment with working knowledge of mammalian cell culture, bioreactors, chromatography, normal flow filtration, tangential flow filtration, high-throughput automation Uses scientific principles and engineering fundamentals to solve problems Ability to design experiments with design of experiment (DOE) approaches, perform experiments, and interpret the results using statistical software (e.g., JMP) Independently motivated with ability to multi-task, problem-solve, and coordinate activities within a team Desire and drive to learn the biological mechanism of cell and gene therapy products and passion for their impact on the lives of patients with serious diseases Ability to communicate clearly and concisely through oral presentation and technical writing Familiarity with process control principles and software as well as programming automated equipment Compensation and Benefits
Seattle - WA: $88,430 - $107,151. The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/. Benefit offerings include Medical, pharmacy, dental and vision care, wellbeing programs, 401(k), disability, life insurance, paid holidays, vacation, and other programs described on the careers site. On-site considerations, accommodation policies, and equal employment opportunity statements apply as described by the company.
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Associate Scientist, Gene Delivery and Editing Process Development Responsibilities
Perform hands-on experimental work in the development and optimization of upstream (cell culture and transfection conditions) and downstream (clarification, chromatography, tangential and normal flow filtration) unit operations for viral vector production. Support process and technology development for viral vector manufacturing platforms utilizing suspension cell culture, transient transfection, purification, and single-use systems. Support development of high-throughput process development tools such as automated multi-parallel bioreactor system (Ambr) and liquid handlers (e.g., Tecan). Design, plan, execute, and analyze lab experiments using statistical design of experiment (DOE) principles. Manage and analyze large data sets. Maintain proper documentation of experimental results using an electronic lab notebook. Summarize and present scientific data; communicate progress to project teams. Author technical documents including protocols and internal development reports. Maintain a safe work environment in accordance with policies/procedures/regulations. Education
M.S. or B.S. in Biological or Chemical Engineering, Virology, Molecular or Cellular Biology, Biochemistry, or related discipline Qualifications
0-2 years of hands-on experience with biological process unit operations and equipment with working knowledge of mammalian cell culture, bioreactors, chromatography, normal flow filtration, tangential flow filtration, high-throughput automation Uses scientific principles and engineering fundamentals to solve problems Ability to design experiments with design of experiment (DOE) approaches, perform experiments, and interpret the results using statistical software (e.g., JMP) Independently motivated with ability to multi-task, problem-solve, and coordinate activities within a team Desire and drive to learn the biological mechanism of cell and gene therapy products and passion for their impact on the lives of patients with serious diseases Ability to communicate clearly and concisely through oral presentation and technical writing Familiarity with process control principles and software as well as programming automated equipment Compensation and Benefits
Seattle - WA: $88,430 - $107,151. The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/. Benefit offerings include Medical, pharmacy, dental and vision care, wellbeing programs, 401(k), disability, life insurance, paid holidays, vacation, and other programs described on the careers site. On-site considerations, accommodation policies, and equal employment opportunity statements apply as described by the company.
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