AbbVie
Senior Principal Research Scientist, Method and Technology Advancements Lead
AbbVie, Cambridge, Massachusetts, us, 02140
Senior Principal Research Scientist, Method and Technology Advancements Lead
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Senior Principal Research Scientist, Method and Technology Advancements Lead
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AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. The Bioinformatics for Immunology, Genetics, and Genomic Sciences group in the Genomics Research Center (GRC) at AbbVie is seeking a highly motivated and experienced AI/ML leader to transform our drug discovery and development through cutting-edge method and technology innovation. This position will be based in Cambridge, Massachusetts (hybrid). The candidate will lead a team of computational biologists and AI/ML experts focused on developing computational innovation to accelerate drug discovery and development across therapeutic and functional areas. Key Responsibilities:
Lead a diverse team of up to 10 FTEs specializing in computational method and novel technology innovation across AbbVie’s therapeutic and functional areas. Design and implement advanced AI/ML algorithms tailored to tackling complex problems across the drug development pipeline. Identify, evaluate, and implement emerging AI/ML methodologies, including state-of-the-art Generative AI, to deliver measurable impact on pipeline productivity and success. Act as the AI/ML expert in program teams, providing guidance and suggestions on cross-functional innovation projects. Develop and implement analytical approaches and best practices for novel technologies such as spatial transcriptomics, long-read sequencing, and CRISPR with strategic partners. Mentor leaders, emerging scientists and build capabilities, fostering an environment of scientific excellence and continuous growth. Communicate analytical approaches and results effectively to scientific and technical audiences. Provide expertise and technical consultation for external collaborations/partnerships in academia and industry. Qualifications:
Basic Qualifications: PhD. in bioinformatics, statistics, mathematics, computer science, computational biology, genomics, or a related field with 8+ years industry/academic experience. Or master’s degree with 15+ years of relevant experience. 3+ years of experience managing direct reports. 5+ years of hands-on experience in analyzing and integrating multi-omics data. 3+ years of hands-on experience developing novel methods including AI and ML approaches. Highly proficient with statistical and programing languages (R, Python), Unix/Linux and cloud computing environment. Preferred Qualifications: At least 3 years of experience managing teams, including managing managers with direct reports, and setting strategic goals for their teams within a highly matrixed organization. Deep understanding of human disease biology across various therapeutic areas such as immunology, aesthetics, and ophthalmology. Experience applying advanced computational modeling and AI/ML approaches to optimize therapeutic protein design, enhance production efficiency, and accelerate genetic medicine development. Expertise in predictive modeling, quantitative data analysis, and novel method development leveraging multi-modal preclinical, clinical, and real-world data. Experience with optimizing and fine-tuning foundation models, and applying LLM, Generative AI, and Agentic AI frameworks to biological questions. Experience with multi-omics data integration and with novel technologies such as spatial transcriptomics, Perturb-seq, CRISPR, long-read sequencing, etc. Demonstrate strong communication skills that allow you to effectively communicate complex technical concepts to diverse audiences and scientific leadership. Collaborative and self-motivated, able to manage multiple objectives and adapt to changing priorities. Strong track record of publications and/or patents in this space. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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Join to apply for the
Senior Principal Research Scientist, Method and Technology Advancements Lead
role at
AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. The Bioinformatics for Immunology, Genetics, and Genomic Sciences group in the Genomics Research Center (GRC) at AbbVie is seeking a highly motivated and experienced AI/ML leader to transform our drug discovery and development through cutting-edge method and technology innovation. This position will be based in Cambridge, Massachusetts (hybrid). The candidate will lead a team of computational biologists and AI/ML experts focused on developing computational innovation to accelerate drug discovery and development across therapeutic and functional areas. Key Responsibilities:
Lead a diverse team of up to 10 FTEs specializing in computational method and novel technology innovation across AbbVie’s therapeutic and functional areas. Design and implement advanced AI/ML algorithms tailored to tackling complex problems across the drug development pipeline. Identify, evaluate, and implement emerging AI/ML methodologies, including state-of-the-art Generative AI, to deliver measurable impact on pipeline productivity and success. Act as the AI/ML expert in program teams, providing guidance and suggestions on cross-functional innovation projects. Develop and implement analytical approaches and best practices for novel technologies such as spatial transcriptomics, long-read sequencing, and CRISPR with strategic partners. Mentor leaders, emerging scientists and build capabilities, fostering an environment of scientific excellence and continuous growth. Communicate analytical approaches and results effectively to scientific and technical audiences. Provide expertise and technical consultation for external collaborations/partnerships in academia and industry. Qualifications:
Basic Qualifications: PhD. in bioinformatics, statistics, mathematics, computer science, computational biology, genomics, or a related field with 8+ years industry/academic experience. Or master’s degree with 15+ years of relevant experience. 3+ years of experience managing direct reports. 5+ years of hands-on experience in analyzing and integrating multi-omics data. 3+ years of hands-on experience developing novel methods including AI and ML approaches. Highly proficient with statistical and programing languages (R, Python), Unix/Linux and cloud computing environment. Preferred Qualifications: At least 3 years of experience managing teams, including managing managers with direct reports, and setting strategic goals for their teams within a highly matrixed organization. Deep understanding of human disease biology across various therapeutic areas such as immunology, aesthetics, and ophthalmology. Experience applying advanced computational modeling and AI/ML approaches to optimize therapeutic protein design, enhance production efficiency, and accelerate genetic medicine development. Expertise in predictive modeling, quantitative data analysis, and novel method development leveraging multi-modal preclinical, clinical, and real-world data. Experience with optimizing and fine-tuning foundation models, and applying LLM, Generative AI, and Agentic AI frameworks to biological questions. Experience with multi-omics data integration and with novel technologies such as spatial transcriptomics, Perturb-seq, CRISPR, long-read sequencing, etc. Demonstrate strong communication skills that allow you to effectively communicate complex technical concepts to diverse audiences and scientific leadership. Collaborative and self-motivated, able to manage multiple objectives and adapt to changing priorities. Strong track record of publications and/or patents in this space. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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