Eli Lilly and Company
Director - Mass Spectrometry-based Biomarker Discovery - Neuroscience
Eli Lilly and Company, Boston, Massachusetts, us, 02298
Overview
Director - Mass Spectrometry-based Biomarker Discovery - Neuroscience at Eli Lilly and Company. Lilly is a global healthcare leader dedicated to advancing therapies for neurological disorders. The Neuroscience Research team focuses on biomarker discovery and validation to support diagnosis, therapeutic management, and trial planning in neurodegenerative diseases. The Director will lead strategic direction and technical execution for biomarker assay development within Lilly’s neuroscience portfolio, based in Boston in a unit led by Dr. Kaj Blennow, Vice President of Neuroscience Biomarker Development. Key Responsibilities
Development and validation of novel mass spectrometry-based assays for early- and late-phase clinical trials in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, ALS, and rare brain disorders. Work with project team leads, and mentor junior associates to design and execute in vitro experiments to support preclinical and clinical characterization and evaluation of therapeutic molecules through biomarker assay development. Assist with the planning and execution of method development, optimization, and sample analyses, coordinating readouts for complex studies with internal and external partners. Implement assay validation procedures to deliver high performance biomarker assays for preclinical and clinical sample analyses. Serve as a scientific and technical expert for in-house and outsourced biomarker discovery efforts, establishing experimental study design and analytical strategies. Collaborate cross-functionally with internal stakeholders (medical, operations, statistics, regulatory) and external partners (CROs, academic institutions) to ensure biomarker validation and integration into clinical programs. Communicate findings through presentations, publications, and strategic discussions, reinforcing Lilly’s leadership in biomarker innovation. Basic Qualifications
PhD in Neuroscience, Biochemistry or a related scientific field, with 5+ years of industry, academic, or postdoctoral experience in biomarker development, with recognized expertise in mass spectrometry-based assays for brain diseases. Additional Skills/Preferences
Must have deep understanding of the mass spectrometry technology and instrumentation as well as mass spectrometry-based assay development and validation for biomarker applications in clinical trials. Must be technically skilled to independently execute advanced mass spectrometry-based studies. Proven leadership in managing and mentoring biomarker research teams in academic or industry settings. Strong strategic thinking, problem-solving abilities, and the ability to drive innovation in biomarker discovery. Excellent communication, collaboration, and negotiation skills to influence both internal and external stakeholders. Demonstrated ability to translate scientific insights into impactful clinical applications. Compensation and Benefits
Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $184,500 - $321,200. Full-time equivalent employees also will be eligible for a company bonus and a comprehensive benefits program including eligibility for a 401(k), pension, vacation, medical/dental/vision, flexible benefits, life and death benefits, time off, and well-being programs. Equal Opportunity and Accessibility
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, and is an EEO Employer. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form. This is for accommodation requests as part of the application process; other correspondence will not receive a response. Our employee resource groups (ERGs) offer support networks for members. Learn more about our groups at Lilly.
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Director - Mass Spectrometry-based Biomarker Discovery - Neuroscience at Eli Lilly and Company. Lilly is a global healthcare leader dedicated to advancing therapies for neurological disorders. The Neuroscience Research team focuses on biomarker discovery and validation to support diagnosis, therapeutic management, and trial planning in neurodegenerative diseases. The Director will lead strategic direction and technical execution for biomarker assay development within Lilly’s neuroscience portfolio, based in Boston in a unit led by Dr. Kaj Blennow, Vice President of Neuroscience Biomarker Development. Key Responsibilities
Development and validation of novel mass spectrometry-based assays for early- and late-phase clinical trials in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, ALS, and rare brain disorders. Work with project team leads, and mentor junior associates to design and execute in vitro experiments to support preclinical and clinical characterization and evaluation of therapeutic molecules through biomarker assay development. Assist with the planning and execution of method development, optimization, and sample analyses, coordinating readouts for complex studies with internal and external partners. Implement assay validation procedures to deliver high performance biomarker assays for preclinical and clinical sample analyses. Serve as a scientific and technical expert for in-house and outsourced biomarker discovery efforts, establishing experimental study design and analytical strategies. Collaborate cross-functionally with internal stakeholders (medical, operations, statistics, regulatory) and external partners (CROs, academic institutions) to ensure biomarker validation and integration into clinical programs. Communicate findings through presentations, publications, and strategic discussions, reinforcing Lilly’s leadership in biomarker innovation. Basic Qualifications
PhD in Neuroscience, Biochemistry or a related scientific field, with 5+ years of industry, academic, or postdoctoral experience in biomarker development, with recognized expertise in mass spectrometry-based assays for brain diseases. Additional Skills/Preferences
Must have deep understanding of the mass spectrometry technology and instrumentation as well as mass spectrometry-based assay development and validation for biomarker applications in clinical trials. Must be technically skilled to independently execute advanced mass spectrometry-based studies. Proven leadership in managing and mentoring biomarker research teams in academic or industry settings. Strong strategic thinking, problem-solving abilities, and the ability to drive innovation in biomarker discovery. Excellent communication, collaboration, and negotiation skills to influence both internal and external stakeholders. Demonstrated ability to translate scientific insights into impactful clinical applications. Compensation and Benefits
Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $184,500 - $321,200. Full-time equivalent employees also will be eligible for a company bonus and a comprehensive benefits program including eligibility for a 401(k), pension, vacation, medical/dental/vision, flexible benefits, life and death benefits, time off, and well-being programs. Equal Opportunity and Accessibility
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, and is an EEO Employer. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form. This is for accommodation requests as part of the application process; other correspondence will not receive a response. Our employee resource groups (ERGs) offer support networks for members. Learn more about our groups at Lilly.
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