Gilead Sciences
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Sr Scientist, Analytical Ops
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Gilead Sciences . Gilead Sciences, Inc. is a research-based biopharmaceutical company founded in 1987. Our mission is to address unmet medical needs and improve life by advancing the care of patients with life-threatening diseases. Our worldwide team collaborates to deliver life-saving therapies and provide access to those therapies globally. Our focus is on scientific innovation, development, and providing opportunities for ongoing professional growth. Key Responsibilities
Support late-stage assay development by performing mass spectrometry to characterize molecules, degradation pathways, and define critical quality attributes in a phase-appropriate context. Contribute to analytical method development and qualification for protein characterization. Develop innovative assays to gain competitive advantages over standard industry practices. Support comparability and stability studies using mass spectrometry. Operate, maintain, and troubleshoot Waters, Sciex, Bruker QTOFs, and Thermo Orbitrap mass spectrometers. Solve complex problems requiring evaluation of intangible variables using logic, ingenuity, and creativity. Collaborate with junior and senior team members to advance state-of-the-art characterization techniques. Represent the Structure Characterization group in cross-functional project teams. Participate in technology transfer of assays to QC and external CRO/CMOs. Coordinate analysis of in-process and product-related impurities for process comparability studies. Conduct scientific research to support drug candidate development and marketed drug research. Advise project teams on experiment planning and execution, considering economic, regulatory, and safety factors. Present results, interpret data, and draw conclusions from experimental findings. Stay current with scientific literature and apply relevant knowledge to projects. Represent the company at national and international conferences. Basic Qualifications
BS degree with at least 8 years of industry experience OR MS degree with at least 6 years of industry experience. Strong knowledge of mass spectrometry, experimental design, and assay development. Demonstrated ability to lead in a cross-functional environment and mentor junior team members. Ability to work independently with minimal supervision. Excellent verbal, technical writing, and interpersonal communication skills. Proficient in Microsoft Office applications. Preferred Qualifications
PhD in Chemistry or related discipline with at least 2 years of industry experience Familiarity with techniques such as: Peptide mapping by LC-MS/MS Intact mass analysis MS/MS for protein and carbohydrate structural elucidation/quantification Kinetic analyses Ultra-performance chromatography Proteolytic/chemical processing Knowledge of ICH guidelines and GMP. Expertise in mass spectrometry analysis software (Protein Metrics, Thermo BioPharma Finder, Skyline). Experience with data analysis and visualization tools (Python, R, JMP, Spotfire). Strong organizational and planning skills. Ability to work effectively in a matrixed environment and communicate assay results and issues clearly. Salary range and benefits: The salary range for this position is $153,935.00 - $199,210.00. This role may be eligible for discretionary bonuses, stock-based incentives, paid time off, and a benefits package including medical, dental, vision, and life insurance plans. For benefits information, visit the company benefits page. Employment details
Seniority level: Not Applicable Employment type: Full-time Job function: Research, Analyst, and Information Technology Industries: Biotechnology Research and Pharmaceutical Manufacturing EEO Notice: Gilead Sciences is an equal opportunity employer and provides a work environment free of harassment and discrimination. We encourage applicants from diverse backgrounds and perspectives. For information about equal employment opportunity protections, please view the Know Your Rights poster.
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Sr Scientist, Analytical Ops
role at
Gilead Sciences . Gilead Sciences, Inc. is a research-based biopharmaceutical company founded in 1987. Our mission is to address unmet medical needs and improve life by advancing the care of patients with life-threatening diseases. Our worldwide team collaborates to deliver life-saving therapies and provide access to those therapies globally. Our focus is on scientific innovation, development, and providing opportunities for ongoing professional growth. Key Responsibilities
Support late-stage assay development by performing mass spectrometry to characterize molecules, degradation pathways, and define critical quality attributes in a phase-appropriate context. Contribute to analytical method development and qualification for protein characterization. Develop innovative assays to gain competitive advantages over standard industry practices. Support comparability and stability studies using mass spectrometry. Operate, maintain, and troubleshoot Waters, Sciex, Bruker QTOFs, and Thermo Orbitrap mass spectrometers. Solve complex problems requiring evaluation of intangible variables using logic, ingenuity, and creativity. Collaborate with junior and senior team members to advance state-of-the-art characterization techniques. Represent the Structure Characterization group in cross-functional project teams. Participate in technology transfer of assays to QC and external CRO/CMOs. Coordinate analysis of in-process and product-related impurities for process comparability studies. Conduct scientific research to support drug candidate development and marketed drug research. Advise project teams on experiment planning and execution, considering economic, regulatory, and safety factors. Present results, interpret data, and draw conclusions from experimental findings. Stay current with scientific literature and apply relevant knowledge to projects. Represent the company at national and international conferences. Basic Qualifications
BS degree with at least 8 years of industry experience OR MS degree with at least 6 years of industry experience. Strong knowledge of mass spectrometry, experimental design, and assay development. Demonstrated ability to lead in a cross-functional environment and mentor junior team members. Ability to work independently with minimal supervision. Excellent verbal, technical writing, and interpersonal communication skills. Proficient in Microsoft Office applications. Preferred Qualifications
PhD in Chemistry or related discipline with at least 2 years of industry experience Familiarity with techniques such as: Peptide mapping by LC-MS/MS Intact mass analysis MS/MS for protein and carbohydrate structural elucidation/quantification Kinetic analyses Ultra-performance chromatography Proteolytic/chemical processing Knowledge of ICH guidelines and GMP. Expertise in mass spectrometry analysis software (Protein Metrics, Thermo BioPharma Finder, Skyline). Experience with data analysis and visualization tools (Python, R, JMP, Spotfire). Strong organizational and planning skills. Ability to work effectively in a matrixed environment and communicate assay results and issues clearly. Salary range and benefits: The salary range for this position is $153,935.00 - $199,210.00. This role may be eligible for discretionary bonuses, stock-based incentives, paid time off, and a benefits package including medical, dental, vision, and life insurance plans. For benefits information, visit the company benefits page. Employment details
Seniority level: Not Applicable Employment type: Full-time Job function: Research, Analyst, and Information Technology Industries: Biotechnology Research and Pharmaceutical Manufacturing EEO Notice: Gilead Sciences is an equal opportunity employer and provides a work environment free of harassment and discrimination. We encourage applicants from diverse backgrounds and perspectives. For information about equal employment opportunity protections, please view the Know Your Rights poster.
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