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Enigma Search

AI Antibody Design Research Scientist

Enigma Search, Redwood City, California, United States, 94061

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Position Overview

Our client is a Stealth Biotechnology company whose core mission is to discover and develop differentiated biologics to treat immunological and other diseases. Our client is seeking a highly motivated AI Antibody Design Research Scientist to join the team. The successful candidate will leverage cutting-edge artificial intelligence and machine learning approaches to advance antibody discovery and design. This role offers the opportunity to work at the intersection of AI, structural biology, and therapeutic development. Key Responsibilities

Research & Development Develop and implement novel AI/ML algorithms for antibody design, optimization, and engineering

Apply and improve protein structure prediction models for antibody-antigen interactions

Design computational workflows for high-throughput antibody screening and optimization

Integrate multi-modal data including sequence, structure, and experimental data

Iteratively fine tune/retrain models based on experimental validation and feedback from wet lab teams

Collaboration & Innovation Stay current with rapidly evolving AI antibody design literature and methodologies

Evaluate and implement state-of-the-art models and tools in the field

Collaborate closely with experimental teams to validate computational predictions

Effectively communicate complex computational concepts and results to experimental scientists

Integrate experimental data as feedback to iteratively improve and fine tune/retrain AI models

Present research findings at scientific conferences and publish in peer-reviewed journals

Required Qualifications and Experience

Ph.D. in Computational Biology, Bioinformatics, Computer Science, Physics, Chemistry, or related field

(Preferred) 1 years of postdoctoral or industry experience in AI antibody design

Demonstrated experience in either: Protein structure modeling and prediction algorithms

Antibody design, engineering, or computational immunology

Experience with diffusion models, pairformer architecture and antibody language models for structure prediction and antibody design

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