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Baylor College of Medicine

Staff Scientist - Microbial Metabolomics/Cell Signaling

Baylor College of Medicine, Houston, Texas, United States, 77246

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Overview

Job Title:

Staff Scientist - Microbial Metabolomics/Cell Signaling Division:

TCH Departments Work Arrangement:

Onsite only Location:

Houston, TX Salary Range:

Hiring up to $80,000 FLSA Status:

Exempt Work Schedule:

Monday – Friday, 8 a.m. – 5 p.m. Summary:

The Texas Children’s Microbiome Center in the Department of Pathology at Texas Children’s Hospital and Baylor College of Medicine is seeking a highly motivated PhD candidate for a Staff Scientist position in microbial metabolomics and microbe:human cell signaling. The Staff Scientist will be part of the Department of Pathology & Immunology at Baylor College of Medicine and will participate in research and development of tools to study host-microbiome interactions under the supervision of James Versalovic, MD, PhD, and will work in the Department of Pathology at Texas Children’s Hospital.

Responsibilities

Designing and troubleshooting experiments

Perform microbial culture and microbial metabolomics using LC-MS methodologies

Culturing microbial strains (e.g., bacteria, fungi) under controlled conditions to study growth, behavior, and metabolic output

Comprehensive analysis of small molecules (metabolites) produced by microbes

Develop human cell-based model systems including cell culture and organoid experiments

Human cell culture: Growing human cells (e.g., epithelial, immune, stem cells) in vitro

Organoid experiments: Creating 3D mini-organs from stem cells that replicate key features of human tissues

Investigation of immune cell responses and myeloid cell differentiation

Immune cell response analysis and myeloid differentiation studies

Flow cytometry, cytokine profiling, transcriptomics

Functional assays to assess phagocytosis, antigen presentation, or inflammatory signaling

Adoption of new techniques and procedures

Computational biology and multi-omics data analysis

Integrating data from Genomics, Transcriptomics, Proteomics, and Metabolomics

Provide technical expertise, training or mentoring to Postdocs, graduate students or staff

Assist with maintenance of computational servers in the Texas Children’s Microbiome Center

Perform other job-related duties as assigned

Qualifications

Minimum:

Doctoral degree. Experience may not be substituted for the degree. Three years of postdoctoral research experience.

Preferred:

Strong background in microbiology and human cell signaling; experience in immunology and drug discovery is favorable.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

Job Details

Seniority level: Mid-Senior level

Employment type: Full-time

Job function: Research

Industries: Higher Education and Research Services

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