BioSpace
Sr. Director, US Value & Access Strategy, Enzyme Therapies
BioSpace, San Rafael, California, United States, 94911
Overview
Sr. Director, US Value & Access Strategy, Enzyme Therapies BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since 1997, BioMarin has applied scientific expertise to understand genetic conditions and create transformative medicines. The organization develops medicines for patients with significant unmet medical need, with a pipeline of commercial, clinical and preclinical candidates. The Commercial organization leads BioMarin’s global sales and marketing strategies. The team solidifies BioMarin’s commercial presence in the United States and Europe and is expanding in other regions. Summary
The Market Access Strategy Sr. Director will lead US value, access, and reimbursement strategy development to ensure optimal patient access and coverage for BioMarin’s Enzyme Therapies business unit. This role aligns cross-functional teams, manages payer and channel strategies, and shapes the external market access environment to support product value and commercial success. The position works closely with stakeholders in the commercial, medical affairs, and corporate functions and reports to the Vice President of US Market Access. The goal is to evaluate the US coverage and reimbursement landscape and provide SME input to influence commercial planning and market entry plans. Responsibilities
Develop and execute U.S. market access strategies to support product launches and ongoing commercialization. Lead payer engagement strategy, including national and regional payers, PBMs, Medicare and Medicaid. Collaborate with pricing, HEOR, government affairs, patient services and field access teams to develop compelling value propositions and evidence plans. Oversee the development of access-related tools and resources (AMCP dossiers, value decks, coverage policies). Coordinate with sales, marketing, medical affairs, and legal teams to ensure alignment on strategy and execution. Monitor policy, reimbursement, and pricing landscape and assess implications for the business. Support contracting strategy development and assist with negotiations as needed. Manage relationships with external vendors, consultants, and payer advisors. Analyze access and utilization data to inform strategy and measure performance. Act as US market access SME/voice for the enzyme therapies business unit within the commercial organization. Required Experience/Skills
Minimum 10+ years of progressive experience in US market access, managed markets, payer strategy, or related pharmaceutical functions. Deep understanding of the U.S. healthcare system, reimbursement mechanisms, and payer landscape. Deep understanding of health policy and health system environment for transformative and rare therapies. Superior problem-solving skills with ability to apply experience to complex policy issues. Excellent communication, collaboration, influence, strategic and analytical skills. Ability to lead cross-functional teams in a fast-paced, dynamic environment. Preferred Qualifications
US launch experience in specialty therapeutics (oncology, rare disease, immunology). Experience with Medicare Part B/D, Medicaid and commercial payers. Familiarity with ICER, QALY models, and evidence-based value frameworks. Understanding of value-based contracting and innovative reimbursement models. Education
Bachelors, preferably in life sciences or economics. MBA or MPH, preferred. Additional
This position is physically located in BioMarin’s corporate offices in San Rafael, CA, with travel approximately 25%. This position has no direct reports. Equal Opportunity Employer/Veterans/Disabled. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
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Sr. Director, US Value & Access Strategy, Enzyme Therapies BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since 1997, BioMarin has applied scientific expertise to understand genetic conditions and create transformative medicines. The organization develops medicines for patients with significant unmet medical need, with a pipeline of commercial, clinical and preclinical candidates. The Commercial organization leads BioMarin’s global sales and marketing strategies. The team solidifies BioMarin’s commercial presence in the United States and Europe and is expanding in other regions. Summary
The Market Access Strategy Sr. Director will lead US value, access, and reimbursement strategy development to ensure optimal patient access and coverage for BioMarin’s Enzyme Therapies business unit. This role aligns cross-functional teams, manages payer and channel strategies, and shapes the external market access environment to support product value and commercial success. The position works closely with stakeholders in the commercial, medical affairs, and corporate functions and reports to the Vice President of US Market Access. The goal is to evaluate the US coverage and reimbursement landscape and provide SME input to influence commercial planning and market entry plans. Responsibilities
Develop and execute U.S. market access strategies to support product launches and ongoing commercialization. Lead payer engagement strategy, including national and regional payers, PBMs, Medicare and Medicaid. Collaborate with pricing, HEOR, government affairs, patient services and field access teams to develop compelling value propositions and evidence plans. Oversee the development of access-related tools and resources (AMCP dossiers, value decks, coverage policies). Coordinate with sales, marketing, medical affairs, and legal teams to ensure alignment on strategy and execution. Monitor policy, reimbursement, and pricing landscape and assess implications for the business. Support contracting strategy development and assist with negotiations as needed. Manage relationships with external vendors, consultants, and payer advisors. Analyze access and utilization data to inform strategy and measure performance. Act as US market access SME/voice for the enzyme therapies business unit within the commercial organization. Required Experience/Skills
Minimum 10+ years of progressive experience in US market access, managed markets, payer strategy, or related pharmaceutical functions. Deep understanding of the U.S. healthcare system, reimbursement mechanisms, and payer landscape. Deep understanding of health policy and health system environment for transformative and rare therapies. Superior problem-solving skills with ability to apply experience to complex policy issues. Excellent communication, collaboration, influence, strategic and analytical skills. Ability to lead cross-functional teams in a fast-paced, dynamic environment. Preferred Qualifications
US launch experience in specialty therapeutics (oncology, rare disease, immunology). Experience with Medicare Part B/D, Medicaid and commercial payers. Familiarity with ICER, QALY models, and evidence-based value frameworks. Understanding of value-based contracting and innovative reimbursement models. Education
Bachelors, preferably in life sciences or economics. MBA or MPH, preferred. Additional
This position is physically located in BioMarin’s corporate offices in San Rafael, CA, with travel approximately 25%. This position has no direct reports. Equal Opportunity Employer/Veterans/Disabled. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
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