Howard Hughes Medical Institute
Postdoctoral Scientist - Wang Lab
Howard Hughes Medical Institute, Northeast Ithaca, New York, United States
Overview
We are seeking a Postdoctoral Scientist to work in the lab of Dr. Michelle Wang, Professor of Physics, J.G. White Distinguished Professor in the Physical Sciences, and HHMI Investigator at Cornell University in Ithaca, NY. The lab aims to understand how transcription and replication can alter DNA topology and how these changes impact these processes. The research combines physics and biology, employing single-molecule techniques to investigate the mechanics and topology of fundamental DNA processes and using theoretical modeling in statistical mechanics and thermodynamics. More information about the lab and publications is available on the lab website. About the position
The successful candidate will carry out projects to investigate the mechanics and topology of fundamental DNA processes using state-of-the-art single-molecule methods pioneered in the lab. The Wang lab has invented several single-molecule manipulation techniques, including the angular optical trap (AOT), the DNA unzipping mapper, tracker, and staller, and the nanophotonic standing-wave array trap (nSWAT). The candidate will have the opportunity to develop novel instruments for topology studies, gain in-depth understanding of data via theoretical and computational modeling, and explore in vivo significance through cellular and genomic studies. They will be part of a dynamic, collaborative team and contribute to unique and exciting science. Application Instructions
Applicants should submit both their curriculum vitae and a detailed statement on how their experience and interests relate to the lab’s work.
Candidate requirements
Ph.D. in physics, biophysics, applied physics, engineering, or a related field.
Proficiency in hands-on experiments, computer programming, and data analysis.
Interest in curiosity-driven inquiries.
Problem-solving skills.
A strong work ethic, self-motivation, and ability to work both independently and in a collaborative environment.
Effective communication skills.
Physical Requirements
Remaining in a normal seated or standing position for extended periods; reaching and grasping; dexterity to manipulate objects (e.g., keyboard); normal vision and hearing; mobility to move about the workspace. The position requires the ability to move materials weighing up to several pounds (e.g., a laptop or tablet). Persons with disabilities may be able to perform essential duties with reasonable accommodation, evaluated on an individual basis. Important Notice
This job description outlines principal duties, responsibilities, and requirements and should not be construed as exhaustive. Essential duties and responsibilities are defined by the Americans with Disabilities Act unless otherwise stated. Compensation and Benefits
We offer competitive pay and a comprehensive benefits package, including health benefits, retirement plans, time off, and wellness programs. Visit the HHMI Benefits site for more information. Compensation Range: $70,000 (minimum) – $80,500 (midpoint) – $91,000 (maximum). Pay Type: Annual. HHMI’s salary structure is based on relevant job market data and candidate qualifications. A new hire at this location is typically compensated between the minimum and midpoint of the salary range. Equal Opportunity Employer
HHMI is an Equal Opportunity Employer. We use E-Verify to confirm the identity and employment eligibility of all new hires.
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We are seeking a Postdoctoral Scientist to work in the lab of Dr. Michelle Wang, Professor of Physics, J.G. White Distinguished Professor in the Physical Sciences, and HHMI Investigator at Cornell University in Ithaca, NY. The lab aims to understand how transcription and replication can alter DNA topology and how these changes impact these processes. The research combines physics and biology, employing single-molecule techniques to investigate the mechanics and topology of fundamental DNA processes and using theoretical modeling in statistical mechanics and thermodynamics. More information about the lab and publications is available on the lab website. About the position
The successful candidate will carry out projects to investigate the mechanics and topology of fundamental DNA processes using state-of-the-art single-molecule methods pioneered in the lab. The Wang lab has invented several single-molecule manipulation techniques, including the angular optical trap (AOT), the DNA unzipping mapper, tracker, and staller, and the nanophotonic standing-wave array trap (nSWAT). The candidate will have the opportunity to develop novel instruments for topology studies, gain in-depth understanding of data via theoretical and computational modeling, and explore in vivo significance through cellular and genomic studies. They will be part of a dynamic, collaborative team and contribute to unique and exciting science. Application Instructions
Applicants should submit both their curriculum vitae and a detailed statement on how their experience and interests relate to the lab’s work.
Candidate requirements
Ph.D. in physics, biophysics, applied physics, engineering, or a related field.
Proficiency in hands-on experiments, computer programming, and data analysis.
Interest in curiosity-driven inquiries.
Problem-solving skills.
A strong work ethic, self-motivation, and ability to work both independently and in a collaborative environment.
Effective communication skills.
Physical Requirements
Remaining in a normal seated or standing position for extended periods; reaching and grasping; dexterity to manipulate objects (e.g., keyboard); normal vision and hearing; mobility to move about the workspace. The position requires the ability to move materials weighing up to several pounds (e.g., a laptop or tablet). Persons with disabilities may be able to perform essential duties with reasonable accommodation, evaluated on an individual basis. Important Notice
This job description outlines principal duties, responsibilities, and requirements and should not be construed as exhaustive. Essential duties and responsibilities are defined by the Americans with Disabilities Act unless otherwise stated. Compensation and Benefits
We offer competitive pay and a comprehensive benefits package, including health benefits, retirement plans, time off, and wellness programs. Visit the HHMI Benefits site for more information. Compensation Range: $70,000 (minimum) – $80,500 (midpoint) – $91,000 (maximum). Pay Type: Annual. HHMI’s salary structure is based on relevant job market data and candidate qualifications. A new hire at this location is typically compensated between the minimum and midpoint of the salary range. Equal Opportunity Employer
HHMI is an Equal Opportunity Employer. We use E-Verify to confirm the identity and employment eligibility of all new hires.
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