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Broad Institute of MIT and Harvard

Research Associate III- Center for the Development of Therapeutics (CDoT)

Broad Institute of MIT and Harvard, Cambridge, Massachusetts, us, 02140

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Overview

Research Associate III- Center for the Development of Therapeutics (CDoT) at Broad Institute of MIT and Harvard. The role focuses on cell biologist/pharmacologist work within the CDoT Cell Pharmacology team to develop and execute novel cell-based assays for target validation, hit discovery and lead optimization, including target engagement and mechanism of action. Ideally, candidates will have experience using multiple assay formats in the context of drug discovery/therapeutics. Responsibilities

Report to a research scientist and work across multi-disciplinary teams to drive the development and execution of novel cell-based assays. Enable target validation, hit discovery, and lead optimization through assay development and implementation. Characterize target engagement and mechanism of action as part of the drug discovery pipeline. Maintain detailed experimental records, documentation, and written protocols. Collaborate effectively within a team and independently to meet project goals in a fast-paced environment. Qualifications

Required: Bachelor’s degree with 2–4 years or Master’s degree with 1–2 years of relevant experience in cell biology, chemical biology, or a related field. Required: Demonstrated experience in culturing, deriving, and maintaining various cell lines. Required: Ability to work both collaboratively and independently to meet project goals; strong documentation skills. Preferred: Experience with plate-based assays and high-throughput screening. Preferred: Familiarity with high-content imaging, microscopy, or molecular biology techniques (e.g., PCR, western blot, ELISA). Preferred: Experience with data analysis using coding languages (e.g., Python, R). Seniority level

Mid-Senior level Employment type

Full-time Job function

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