AIRNA
Research Associate / Senior Research Associate, Preclinical Development
AIRNA, Cambridge, Massachusetts, us, 02140
Research Associate / Senior Research Associate, Preclinical Development
AIRNA is seeking a highly motivated Research Associate/Senior Research Associate to join our Preclinical Development team in Cambridge, MA and assist in executing activities associated with AIRNA's drug development programs advancing novel therapeutics to the clinic.
As a member of AIRNA’s Preclinical team, you will be involved in the development and execution of biochemical and cell-based assays for RNA-modifying oligonucleotides. Your responsibilities will include:
Working independently or with minimal supervision to develop, and qualify biochemical and next generation sequencing-based assays.
Preparing RNA and proteins from cell or animal samples and analyzing these samples by qPCR, ELISA, MSD, next-generation sequencing, or Western blot analysis.
Generating detailed study summaries and preparing reports for regulatory submission.
Performing general lab duties such as maintenance of lab equipment and reagent preparations.
Maintaining accurate and complete records in an electronic notebook; preparing and updating documentation as needed (SOP, Batch Records, etc.).
Ensuring compliance with company policies, procedures, and safety regulations.
Being a positive, collaborative, and committed team member.
QUALIFICATIONS
Bachelor's degree in Biological Sciences, Biochemistry, Molecular Biology, or Pharmaceutical Sciences.
1 - 5 years of relevant working experience in industry. Experience in the field of oligonucleotide therapies is highly desirable.
Previous experience in oligonucleotide PK and PD assays.
Demonstrated ability to execute next generation sequencing-based assays, including primer design, PCR optimization, RT-qPCR, operation of a benchtop sequencer, and QC and basic processing of sequencing data.
Experience with aseptic laboratory technique required.
Timely and detailed experimental documentation.
Being detail-oriented with strong analytical and trouble-shooting skills.
Working familiarity with command line, Python, Microsoft Office, and PRISM.
Demonstrated ability to work as part of a team and to adapt within a fast-changing environment.
REQUIREMENTS
Biotechnology or pharmaceutical industry experience.
Experience in bioanalytical assay development and qualification based on regulatory guidelines.
Experience in using automatic liquid handlers and performing assays in 96+ plate formats.
Experience in sequencing library preparation and data processing.
LOCATION
AIRNA has a hybrid work model, and the role will be based in AIRNA’s corporate headquarters in Cambridge, MA ~4 days per week.
Seniority level
Entry level
Employment type
Full-time
Job function
Research, Analyst, and Information Technology
Note: This refined description focuses on responsibilities, qualifications, and requirements tied to the role and removes extraneous site-wide prompts and duplicates present in the original content.
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As a member of AIRNA’s Preclinical team, you will be involved in the development and execution of biochemical and cell-based assays for RNA-modifying oligonucleotides. Your responsibilities will include:
Working independently or with minimal supervision to develop, and qualify biochemical and next generation sequencing-based assays.
Preparing RNA and proteins from cell or animal samples and analyzing these samples by qPCR, ELISA, MSD, next-generation sequencing, or Western blot analysis.
Generating detailed study summaries and preparing reports for regulatory submission.
Performing general lab duties such as maintenance of lab equipment and reagent preparations.
Maintaining accurate and complete records in an electronic notebook; preparing and updating documentation as needed (SOP, Batch Records, etc.).
Ensuring compliance with company policies, procedures, and safety regulations.
Being a positive, collaborative, and committed team member.
QUALIFICATIONS
Bachelor's degree in Biological Sciences, Biochemistry, Molecular Biology, or Pharmaceutical Sciences.
1 - 5 years of relevant working experience in industry. Experience in the field of oligonucleotide therapies is highly desirable.
Previous experience in oligonucleotide PK and PD assays.
Demonstrated ability to execute next generation sequencing-based assays, including primer design, PCR optimization, RT-qPCR, operation of a benchtop sequencer, and QC and basic processing of sequencing data.
Experience with aseptic laboratory technique required.
Timely and detailed experimental documentation.
Being detail-oriented with strong analytical and trouble-shooting skills.
Working familiarity with command line, Python, Microsoft Office, and PRISM.
Demonstrated ability to work as part of a team and to adapt within a fast-changing environment.
REQUIREMENTS
Biotechnology or pharmaceutical industry experience.
Experience in bioanalytical assay development and qualification based on regulatory guidelines.
Experience in using automatic liquid handlers and performing assays in 96+ plate formats.
Experience in sequencing library preparation and data processing.
LOCATION
AIRNA has a hybrid work model, and the role will be based in AIRNA’s corporate headquarters in Cambridge, MA ~4 days per week.
Seniority level
Entry level
Employment type
Full-time
Job function
Research, Analyst, and Information Technology
Note: This refined description focuses on responsibilities, qualifications, and requirements tied to the role and removes extraneous site-wide prompts and duplicates present in the original content.
#J-18808-Ljbffr