Quest Diagnostics
Staff Scientist, Bioinformatics (Hybrid)
Quest Diagnostics, Buffalo, New York, United States, 14266
Overview
Staff Scientist, Bioinformatics (Hybrid) – Quest Diagnostics. Join to contribute to the development and implementation of bioinformatics methods that directly impact cancer patient care, enabling improved monitoring and informed treatment decisions. This role is hybrid, requiring 3 days onsite per week at our Marlborough, MA facility. Responsibilities
Design, develop, and optimize bioinformatics pipelines for MRD test development and clinical deployment. Analyze high-throughput NGS data and drive performance and scientific insights to support research and development of on-market and upcoming products. Collaborate with laboratory scientists, clinicians, and software engineers to validate and integrate bioinformatics solutions into clinical workflows. Support regulatory and quality documentation, including validation reports, standard operating procedures, and compliance with CLIA/CAP and other quality and regulatory standards. Provide scientific and technical leadership in bioinformatics, mentoring junior team members and guiding best practices. Stay current with advancements in oncology genomics, liquid biopsy, and computational biology methods to inform innovation and future product enhancement. Identify problems, investigate alternatives, and recommend possible courses of action; contribute to technical decisions. Prepare and present information at project meetings, scientific and technical meetings/conferences, and to customers. Qualifications
Ph.D. or M.S. with extensive industry experience. 5+ years of hands-on experience analyzing NGS data, preferably in oncology diagnostics. Strong programming skills in Python, R, or equivalent platforms. Strong logical reasoning skills with the ability to drive solutions for challenging oncology diagnostics problems. Proven expertise in variant calling, error suppression, and ultra-sensitive detection of low-frequency variants. Expertise with cloud-based computational environments (AWS or similar). Demonstrated ability to work in regulated clinical or diagnostic environments (e.g., CLIA, CAP, or FDA submissions). Preferred Work Experience
Ph.D. in Bioinformatics, computational biology, genomics, or related fields. Physical And Mental Requirements
Sitting for long periods; ability to handle multi-tasking and maintain composure under pressure. Adaptability to change; ability to grasp information quickly and follow verbal or written instructions. Effective verbal and written communication; analytical thinking. Ability to concentrate on tasks and manage stress. Knowledge
Advanced degree (M.S./Ph.D.) in Genomics, Computational Biology, Computer Science, or related discipline. Knowledge of related products and technologies in an academic or industrial setting. Skills
Mathematical skills and reasoning ability. Ability to read, interpret, and write professional reports; effective in small group and remote communications. Team And Compliance
Quest Diagnostics is an equal opportunity employer. We honor service members and veterans are encouraged to apply. We do not accept unsolicited resumes from agencies. Quest Diagnostics is committed to equal opportunity for all applicants and employees: Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Veterans or any other legally protected status.
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Staff Scientist, Bioinformatics (Hybrid) – Quest Diagnostics. Join to contribute to the development and implementation of bioinformatics methods that directly impact cancer patient care, enabling improved monitoring and informed treatment decisions. This role is hybrid, requiring 3 days onsite per week at our Marlborough, MA facility. Responsibilities
Design, develop, and optimize bioinformatics pipelines for MRD test development and clinical deployment. Analyze high-throughput NGS data and drive performance and scientific insights to support research and development of on-market and upcoming products. Collaborate with laboratory scientists, clinicians, and software engineers to validate and integrate bioinformatics solutions into clinical workflows. Support regulatory and quality documentation, including validation reports, standard operating procedures, and compliance with CLIA/CAP and other quality and regulatory standards. Provide scientific and technical leadership in bioinformatics, mentoring junior team members and guiding best practices. Stay current with advancements in oncology genomics, liquid biopsy, and computational biology methods to inform innovation and future product enhancement. Identify problems, investigate alternatives, and recommend possible courses of action; contribute to technical decisions. Prepare and present information at project meetings, scientific and technical meetings/conferences, and to customers. Qualifications
Ph.D. or M.S. with extensive industry experience. 5+ years of hands-on experience analyzing NGS data, preferably in oncology diagnostics. Strong programming skills in Python, R, or equivalent platforms. Strong logical reasoning skills with the ability to drive solutions for challenging oncology diagnostics problems. Proven expertise in variant calling, error suppression, and ultra-sensitive detection of low-frequency variants. Expertise with cloud-based computational environments (AWS or similar). Demonstrated ability to work in regulated clinical or diagnostic environments (e.g., CLIA, CAP, or FDA submissions). Preferred Work Experience
Ph.D. in Bioinformatics, computational biology, genomics, or related fields. Physical And Mental Requirements
Sitting for long periods; ability to handle multi-tasking and maintain composure under pressure. Adaptability to change; ability to grasp information quickly and follow verbal or written instructions. Effective verbal and written communication; analytical thinking. Ability to concentrate on tasks and manage stress. Knowledge
Advanced degree (M.S./Ph.D.) in Genomics, Computational Biology, Computer Science, or related discipline. Knowledge of related products and technologies in an academic or industrial setting. Skills
Mathematical skills and reasoning ability. Ability to read, interpret, and write professional reports; effective in small group and remote communications. Team And Compliance
Quest Diagnostics is an equal opportunity employer. We honor service members and veterans are encouraged to apply. We do not accept unsolicited resumes from agencies. Quest Diagnostics is committed to equal opportunity for all applicants and employees: Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Veterans or any other legally protected status.
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