St. Jude Children's Research Hospital
Principal/Lead Bioinformatics Research Scientist
St. Jude Children's Research Hospital, Lauderdale Courts, Tennessee, United States
Overview
The Principal/Lead Bioinformatics Research Scientist functions independently to coordinate large-scale bioinformatics projects, providing project oversight, scientific and technical advice, programming support, and other input as required to achieve established objectives. Coordinates the specialized expertise of bioinformatics colleagues to achieve scientific objectives. Establishes best practice recommendations, creates educational materials, and participates in educational initiatives at the laboratory, departmental, and/or institutional level. The Department of Host-Microbe Interactions seeks a talented and highly motivated Principal Bioinformatics Research Scientist or Lead Bioinformatics Research Scientist with extensive experience in large-scale microbial genomic data analysis to create and direct the Microbial Computational Genomics and Bioinformatics Laboratory at St. Jude Children\'s Research Hospital. The laboratory\'s mission is to support initiatives on microbial genomic, phylogenomic, and computational needs of researchers in the Department of Host-Microbe Interactions and the Center for Infectious Disease Research. The laboratory is a major initiative backed by substantial support as part of our institutional strategic plan and will be integrated with research in microbial evolution, microbial pathogenesis, virology, the microbiome, computational biology, and data sciences at St. Jude. Position focus
The focus of this position is on bacterial and viral genomics, using specimens and data obtained from our healthcare system to address key questions such as the acquisition of antimicrobial resistance, genome heterogeneity, outbreaks, transmission, and the identification of potential targets for the generation of novel therapies. This will be achieved using a combination of approaches, including short- and long-read whole genome sequencing; phylogenomic, transcriptomic, and bioinformatics approaches involving electronic health data; and experimental data generated by collaborating partners. Data analysis will focus on answering clinical questions, generating insights to prevent infections, and building predictive models of disease susceptibility. Responsibilities
Develop and apply state-of-the-art computational approaches to characterize and assemble microbial genomes and metagenomes. Assemble and lead a team of Ph.D.- and MS-level bioinformaticians and data scientists to analyze and interpret newly generated as well as existing large collections of microbial whole-genome sequences and metagenomes. Attract, recruit, and supervise staff to create a strong operational team for the Microbial Computational Genomics and Bioinformatics Laboratory. Collaborate with the St. Jude data science initiative to develop computational pipelines for handling large, complex genomic datasets requiring custom approaches for project-specific analyses. Interface and collaborate with the IT department to develop and maintain capabilities for analysis, interpretation, and storage of genomic data. Maintain a high level of professional expertise through familiarity with scientific literature and networking. Create and implement educational and outreach programs to enhance microbial genomics capabilities within the St. Jude community. Train MS and PhD level graduate students in microbial computational genomics. Collaborate and enable external funding applications. Minimum Education
Bachelor\'s degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. Master\'s degree or PhD preferred. Experience levels
Principal Bioinformatic Research Scientist Minimum Requirement: Bachelor\'s degree with 13+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). Experience Exception: Master\'s degree with 11+ years of relevant post-degree experience (OR) PhD with 8+ years of relevant post-degree experience. Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Lead Bioinformatic Research Scientist Minimum Requirement: Bachelor\'s degree with 10+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). Experience Exception: Master\'s degree with 8+ years of relevant post-degree experience (OR) PhD with 5+ years of relevant post-degree experience. Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors such as skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $138,320 - $262,080 per year for the role of Principal/Lead Bioinformatics Research Scientist. Explore our exceptional benefits! Diversity, Equity and Inclusion
St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family\'s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital\'s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. St. Jude is an Equal Opportunity Employer No Search Firms
St. Jude Children\'s Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
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The Principal/Lead Bioinformatics Research Scientist functions independently to coordinate large-scale bioinformatics projects, providing project oversight, scientific and technical advice, programming support, and other input as required to achieve established objectives. Coordinates the specialized expertise of bioinformatics colleagues to achieve scientific objectives. Establishes best practice recommendations, creates educational materials, and participates in educational initiatives at the laboratory, departmental, and/or institutional level. The Department of Host-Microbe Interactions seeks a talented and highly motivated Principal Bioinformatics Research Scientist or Lead Bioinformatics Research Scientist with extensive experience in large-scale microbial genomic data analysis to create and direct the Microbial Computational Genomics and Bioinformatics Laboratory at St. Jude Children\'s Research Hospital. The laboratory\'s mission is to support initiatives on microbial genomic, phylogenomic, and computational needs of researchers in the Department of Host-Microbe Interactions and the Center for Infectious Disease Research. The laboratory is a major initiative backed by substantial support as part of our institutional strategic plan and will be integrated with research in microbial evolution, microbial pathogenesis, virology, the microbiome, computational biology, and data sciences at St. Jude. Position focus
The focus of this position is on bacterial and viral genomics, using specimens and data obtained from our healthcare system to address key questions such as the acquisition of antimicrobial resistance, genome heterogeneity, outbreaks, transmission, and the identification of potential targets for the generation of novel therapies. This will be achieved using a combination of approaches, including short- and long-read whole genome sequencing; phylogenomic, transcriptomic, and bioinformatics approaches involving electronic health data; and experimental data generated by collaborating partners. Data analysis will focus on answering clinical questions, generating insights to prevent infections, and building predictive models of disease susceptibility. Responsibilities
Develop and apply state-of-the-art computational approaches to characterize and assemble microbial genomes and metagenomes. Assemble and lead a team of Ph.D.- and MS-level bioinformaticians and data scientists to analyze and interpret newly generated as well as existing large collections of microbial whole-genome sequences and metagenomes. Attract, recruit, and supervise staff to create a strong operational team for the Microbial Computational Genomics and Bioinformatics Laboratory. Collaborate with the St. Jude data science initiative to develop computational pipelines for handling large, complex genomic datasets requiring custom approaches for project-specific analyses. Interface and collaborate with the IT department to develop and maintain capabilities for analysis, interpretation, and storage of genomic data. Maintain a high level of professional expertise through familiarity with scientific literature and networking. Create and implement educational and outreach programs to enhance microbial genomics capabilities within the St. Jude community. Train MS and PhD level graduate students in microbial computational genomics. Collaborate and enable external funding applications. Minimum Education
Bachelor\'s degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. Master\'s degree or PhD preferred. Experience levels
Principal Bioinformatic Research Scientist Minimum Requirement: Bachelor\'s degree with 13+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). Experience Exception: Master\'s degree with 11+ years of relevant post-degree experience (OR) PhD with 8+ years of relevant post-degree experience. Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Lead Bioinformatic Research Scientist Minimum Requirement: Bachelor\'s degree with 10+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). Experience Exception: Master\'s degree with 8+ years of relevant post-degree experience (OR) PhD with 5+ years of relevant post-degree experience. Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors such as skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $138,320 - $262,080 per year for the role of Principal/Lead Bioinformatics Research Scientist. Explore our exceptional benefits! Diversity, Equity and Inclusion
St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family\'s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital\'s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. St. Jude is an Equal Opportunity Employer No Search Firms
St. Jude Children\'s Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
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