US Tech Solutions
This range is provided by US Tech Solutions. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.
Base pay range $40.00/hr - $60.00/hr
Direct message the job poster from US Tech Solutions
Team Lead @ US Tech Solutions | Recruitment, Delivery, Stakeholder Management. Duration: 12 months contract
Description:
Job Title:
Scientist I / Scientist II
Duration:
12 Months + ( Possible temp to perm position )
General Position Summary/Purpose The Cell Line Development Group in South San Francisco, CA is seeking a Scientist I/II to join a talented and collaborative team developing CHO cell lines for
GMP applications . In this laboratory position the candidate will perform hands-on CHO cell line development and characterization
studies
in a well-supported and dynamic environment to help advance novel biotherapeutics into human clinical studies. The work will encompass molecular, cellular, and bioprocess development studies relating to the generation and characterization of optimized CHO cell lines for production of our
cancer pipeline candidates .
Key Responsibilities
Perform CHO cell line development, including
transfection, selection, single cell subcloning , growth and productivity screening, cell banking and stability assessment of cell banks.
Design and generate
DNA vector constructs
for protein including monoclonal antibodies and antibody-like molecules
Culture mammalian cells across multiple scales and formats, from 96-well plates up to shake flasks.
Operate instruments like ViCell automated cell counter, Octet, Clone Select Imager, microscope, HPLC, ambr15, Beacon and flow cytometer. Share responsibility for equipment maintenance.
Perform genetic characterization of cell banks using molecular techniques like DNA sequencing and PCR.
Review DNA sequencing data (including NGS), Southern/Northern blots, quantitative PCR results.
Author and review cell line development technical reports that meet expectations of regulatory agencies for all stages from IND to BLA.
Present updates at cross-functional meetings and collaborate closely with cell culture, purification, analytical and formulation development colleagues to meet project timelines.
Actively seek opportunities to optimize or enhance the cell line development workflow.
May publish or present scientific findings in peer-reviewed journals, internal or external conferences or consortia.
Display effective organization, verbal and written communication skills, and adherence to good documentation practices.
Qualifications Basic
Scientist I:
BS with a minimum of 5 years
or
MS with a minimum of 3 years
of relevant experience
Scientist II:
BS with a minimum of 7 years
or
MS with a minimum of 5 years
of relevant experience
Proficient in aseptic techniques, mammalian cell culture and basic molecular biology techniques (molecular cloning, plasmid preps, DNA digests/gels, PCR/qPCR)
Experienced in developing
stably transfected CHO cell lines
for production of
monoclonal antibodies
and antibody-like molecules.
Strong understanding of mammalian cell biology and molecular biology concepts.
Must have excellent attention to detail and must keep detailed records in
electronic lab notebook
on a daily basis.
Demonstrated ability to independently design, execute and interpret critical experiments to answer scientific questions.
Demonstrated ability to learn, understand and master new experimental techniques.
Demonstrated ability to work collaboratively within and outside of the group.
Demonstrated ability to author technical reports and presentations.
Proficient with Microsoft Office software and able to learn new software applications.
Able to multi-task and work within timelines.
Strong communication skills – verbal, written, scientific data presentation.
Preferred
Background in
CHO cell line development
for
GMP applications
within
biotech/pharma industry .
Understanding of cell biology and bioprocess engineering concepts.
Hands-on experience running RNA-seq workflow and analysis
Experience in bioinformatics software to analyze DNA and RNA for sequence confirmation and expression analysis
Proficiency in programming/data science languages, such as R, Python, and Java
Experience with flow cytometry
Experience with ddPCR
Experience with ambr15 operation
About US Tech Solutions US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit www.ustechsolutions.com.
US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
Recruiter’s email id: satish.prasad@ustechsolutionsinc.com
Job ID:
25-48538
Seniority level Mid-Senior level
Employment type Contract
Job function Research and Science Industries: Pharmaceutical Manufacturing, Biotechnology Research, and Hospitals and Health Care
Referrals increase your chances of interviewing at US Tech Solutions by 2x
Get notified about new Biologist jobs in
South San Francisco, CA .
San Francisco, CA $90,000.00-$100,000.00 1 day ago
Oakland, CA $50,000.00-$75,000.00 2 months ago
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Base pay range $40.00/hr - $60.00/hr
Direct message the job poster from US Tech Solutions
Team Lead @ US Tech Solutions | Recruitment, Delivery, Stakeholder Management. Duration: 12 months contract
Description:
Job Title:
Scientist I / Scientist II
Duration:
12 Months + ( Possible temp to perm position )
General Position Summary/Purpose The Cell Line Development Group in South San Francisco, CA is seeking a Scientist I/II to join a talented and collaborative team developing CHO cell lines for
GMP applications . In this laboratory position the candidate will perform hands-on CHO cell line development and characterization
studies
in a well-supported and dynamic environment to help advance novel biotherapeutics into human clinical studies. The work will encompass molecular, cellular, and bioprocess development studies relating to the generation and characterization of optimized CHO cell lines for production of our
cancer pipeline candidates .
Key Responsibilities
Perform CHO cell line development, including
transfection, selection, single cell subcloning , growth and productivity screening, cell banking and stability assessment of cell banks.
Design and generate
DNA vector constructs
for protein including monoclonal antibodies and antibody-like molecules
Culture mammalian cells across multiple scales and formats, from 96-well plates up to shake flasks.
Operate instruments like ViCell automated cell counter, Octet, Clone Select Imager, microscope, HPLC, ambr15, Beacon and flow cytometer. Share responsibility for equipment maintenance.
Perform genetic characterization of cell banks using molecular techniques like DNA sequencing and PCR.
Review DNA sequencing data (including NGS), Southern/Northern blots, quantitative PCR results.
Author and review cell line development technical reports that meet expectations of regulatory agencies for all stages from IND to BLA.
Present updates at cross-functional meetings and collaborate closely with cell culture, purification, analytical and formulation development colleagues to meet project timelines.
Actively seek opportunities to optimize or enhance the cell line development workflow.
May publish or present scientific findings in peer-reviewed journals, internal or external conferences or consortia.
Display effective organization, verbal and written communication skills, and adherence to good documentation practices.
Qualifications Basic
Scientist I:
BS with a minimum of 5 years
or
MS with a minimum of 3 years
of relevant experience
Scientist II:
BS with a minimum of 7 years
or
MS with a minimum of 5 years
of relevant experience
Proficient in aseptic techniques, mammalian cell culture and basic molecular biology techniques (molecular cloning, plasmid preps, DNA digests/gels, PCR/qPCR)
Experienced in developing
stably transfected CHO cell lines
for production of
monoclonal antibodies
and antibody-like molecules.
Strong understanding of mammalian cell biology and molecular biology concepts.
Must have excellent attention to detail and must keep detailed records in
electronic lab notebook
on a daily basis.
Demonstrated ability to independently design, execute and interpret critical experiments to answer scientific questions.
Demonstrated ability to learn, understand and master new experimental techniques.
Demonstrated ability to work collaboratively within and outside of the group.
Demonstrated ability to author technical reports and presentations.
Proficient with Microsoft Office software and able to learn new software applications.
Able to multi-task and work within timelines.
Strong communication skills – verbal, written, scientific data presentation.
Preferred
Background in
CHO cell line development
for
GMP applications
within
biotech/pharma industry .
Understanding of cell biology and bioprocess engineering concepts.
Hands-on experience running RNA-seq workflow and analysis
Experience in bioinformatics software to analyze DNA and RNA for sequence confirmation and expression analysis
Proficiency in programming/data science languages, such as R, Python, and Java
Experience with flow cytometry
Experience with ddPCR
Experience with ambr15 operation
About US Tech Solutions US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit www.ustechsolutions.com.
US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
Recruiter’s email id: satish.prasad@ustechsolutionsinc.com
Job ID:
25-48538
Seniority level Mid-Senior level
Employment type Contract
Job function Research and Science Industries: Pharmaceutical Manufacturing, Biotechnology Research, and Hospitals and Health Care
Referrals increase your chances of interviewing at US Tech Solutions by 2x
Get notified about new Biologist jobs in
South San Francisco, CA .
San Francisco, CA $90,000.00-$100,000.00 1 day ago
Oakland, CA $50,000.00-$75,000.00 2 months ago
#J-18808-Ljbffr