Merck
Overview
Our Company is seeking exceptional chemists for positions within the Discovery Chemistry Department. The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent novel medicines by applying innovative synthetic chemistry, analytical techniques, and data analysis to design and synthesize drug candidates and intermediates. In addition, you’ll have the opportunity to expand your knowledge and skills through collaborations with talented and dedicated colleagues while advancing your career. Specific Responsibilities
Act as an expert in the laboratory, executing on program and chemistry strategy. Develop and utilize innovative synthetic, medicinal chemistry and/or chemical biology problem solving skills coupled with analysis of diverse data sets to build structure-activity relationships. Design, synthesize, purify, and characterize drug candidates and/or chemical probes in target identification and validation, hit-to-lead, and lead optimization programs. Provide scientific mentoring and technical training of team members. Establish a substantial external scientific presence including authoring significant scientific publications and presentations. Education
B.S in chemistry, medicinal chemistry, biochemistry, biophysics, or related scientific discipline with seven (7) years’ experience, M.S. in related fields with four (4) years’ experience, or a Ph.D. in related fields (received by Summer 2026) with 0-2 years’ experience. Requirements
Extensive experience in organic synthesis with emphasis on methodology/catalysis, total synthesis, and/or physical organic chemistry. Ability to solve complex problems. As An Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics. As a Federal Contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment Laws, visit the EEOC Know Your Rights and EEOC GINA Supplement pages. We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Required Skills: Adaptability, Analytical Method Development, Bioanalysis, Chemical Biology, Chemical Physics, Chemical Synthesis, Chemistry, Chemometrics, Chromatography, Collaborative Communications, Data Analysis, Drug Development, Flow Cytometry, Immunochemistry, Interpersonal Communication, Mass Spectrometry Based Proteomics, Medicinal Chemistry, Organic Chemistry, Organic Synthesis, Physical Organic Chemistry (+5 more). Preferred Skills: Hit to Lead, Lead Optimization. Compensation and Benefits
The salary range for this role is $128,800.00 - $202,700.00. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. We offer a comprehensive benefits package including medical, dental, vision, retirement benefits (401(k)), paid holidays, vacation, and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits. Additional Information
Hybrid work model: Effective September 5, 2023, U.S. employees in office-based roles will work a hybrid schedule of three on-site days per week, with Friday remote, unless business critical tasks require on-site presence. This model does not apply to field-based, facility-based, manufacturing-based, or research-based positions where work is located at a company site, nor to roles designated as remote. US and Puerto Rico residents only: the company is committed to inclusion and provides accommodations during the application or hiring process if needed. Job Posting End Date: 10/22/2025. Requisition ID: R367632.
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Our Company is seeking exceptional chemists for positions within the Discovery Chemistry Department. The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent novel medicines by applying innovative synthetic chemistry, analytical techniques, and data analysis to design and synthesize drug candidates and intermediates. In addition, you’ll have the opportunity to expand your knowledge and skills through collaborations with talented and dedicated colleagues while advancing your career. Specific Responsibilities
Act as an expert in the laboratory, executing on program and chemistry strategy. Develop and utilize innovative synthetic, medicinal chemistry and/or chemical biology problem solving skills coupled with analysis of diverse data sets to build structure-activity relationships. Design, synthesize, purify, and characterize drug candidates and/or chemical probes in target identification and validation, hit-to-lead, and lead optimization programs. Provide scientific mentoring and technical training of team members. Establish a substantial external scientific presence including authoring significant scientific publications and presentations. Education
B.S in chemistry, medicinal chemistry, biochemistry, biophysics, or related scientific discipline with seven (7) years’ experience, M.S. in related fields with four (4) years’ experience, or a Ph.D. in related fields (received by Summer 2026) with 0-2 years’ experience. Requirements
Extensive experience in organic synthesis with emphasis on methodology/catalysis, total synthesis, and/or physical organic chemistry. Ability to solve complex problems. As An Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics. As a Federal Contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment Laws, visit the EEOC Know Your Rights and EEOC GINA Supplement pages. We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Required Skills: Adaptability, Analytical Method Development, Bioanalysis, Chemical Biology, Chemical Physics, Chemical Synthesis, Chemistry, Chemometrics, Chromatography, Collaborative Communications, Data Analysis, Drug Development, Flow Cytometry, Immunochemistry, Interpersonal Communication, Mass Spectrometry Based Proteomics, Medicinal Chemistry, Organic Chemistry, Organic Synthesis, Physical Organic Chemistry (+5 more). Preferred Skills: Hit to Lead, Lead Optimization. Compensation and Benefits
The salary range for this role is $128,800.00 - $202,700.00. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. We offer a comprehensive benefits package including medical, dental, vision, retirement benefits (401(k)), paid holidays, vacation, and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits. Additional Information
Hybrid work model: Effective September 5, 2023, U.S. employees in office-based roles will work a hybrid schedule of three on-site days per week, with Friday remote, unless business critical tasks require on-site presence. This model does not apply to field-based, facility-based, manufacturing-based, or research-based positions where work is located at a company site, nor to roles designated as remote. US and Puerto Rico residents only: the company is committed to inclusion and provides accommodations during the application or hiring process if needed. Job Posting End Date: 10/22/2025. Requisition ID: R367632.
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