Trilogie Bioscience
Overview
Founded in 2024, Trilogie Bioscience leverages decades of Ubiquitin-Proteasome-System (UPS) experience to support the Targeted Protein Degradation (TPD) industry, non-TPD therapeutic approaches, and the UPS academic community. This is an excellent opportunity for a motivated Scientist to join a company on the ground floor. We aim to produce the best quality UPS protein reagents, assays, and custom services. Your contributions will have an immediate impact. We are seeking collaborative, relentless problem solvers who share our passion for making an impact. Responsibilities
The Product Scientist is a proven protein scientist with expertise in in vitro assay development and the design and production of highly active recombinant proteins. He/she will have expertise in a wide range of protein biochemistry, molecular biology, and assay techniques and workflows. Design, develop and optimize robust, in vitro ubiquitylation, deubiquitylation and proximity assays using Alpha, HTRF, FP, luminescence, spectral shift and other techniques. Implement quality control standards for assay performance, including dynamic range, limit of detection, precision and linearity. Execute screening campaigns for clients, including sample preparation, reagent handling, and assay execution. Validate assay performance through quality control parameters. Analyze and interpret experimental data and prepare detailed reports and documentation. Design and produce multi-component assay kits for retail distribution, including all required reagents, detailed protocols and example dataset. Provide technical expertise and support to customers to facilitate the successful use of assay kits. Assist in the development and optimization of recombinant protein production processes to ensure successful product launch. Collaborate with production team to validate manufacturing protocols, troubleshoot issues, and ensure product quality and consistency. Support new product launch and product release cycle. Collaborate with sales and marketing teams to ensure scientific accuracy of product descriptions. Prepare webinars, abstracts and present posters at scientific meetings. Maintain up-to-date knowledge of product offerings and scientific developments relevant to customer applications. Stay abreast of the latest advancements in UPS and TPD fields by regularly reviewing scientific literature and publications. Seek advice from subject matter experts to enhance knowledge, inform decision-making, and ensure the application of cutting-edge scientific approaches in designing and executing in vitro assays/applications. Generate detailed datasheets for new reagents including product description, usage statements, quality-control data and references. Provide technical support to customers and resolve any technical issues. All other duties as assigned Required Skills and Experience
PhD in a scientific field (Biochemistry, Protein Chemistry) or related discipline, with 2-5 years of post-doctoral work. Expertise in design and implementation of in vitro enzymatic and proximity assays amenable to medium-to-high throughput screening campaigns (FP, HTRF, SPR, Alpha, etc). Experience writing, editing, and creating various types of long- and short-form content including but no limited too application notes, test cases, customer facing content. Strong written, verbal, analytical, research, and communication skills. Experience with liquid handling and laboratory automation, including dataset management a plus. A resourceful problem solver with the ability to manage multiple ongoing projects and meet deadlines. Meticulous attention to detail. Interest in building a deep understanding of technical platforms, and the ability to translate that knowledge into relevant and valuable content This is a full-time, on-site role. Equal Opportunity
Trilogie Bioscience, Inc. is an Equal Opportunity employer and does not discriminate against an applicant or employee because of race, creed, color, religion, sex, national origin, ancestry, age, sexual orientation, physical or mental disability, or veteran status. Additional Information
Seniority level: Mid-Senior level Employment type: Full-time Job function: Research, Analyst, and Information Technology
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Founded in 2024, Trilogie Bioscience leverages decades of Ubiquitin-Proteasome-System (UPS) experience to support the Targeted Protein Degradation (TPD) industry, non-TPD therapeutic approaches, and the UPS academic community. This is an excellent opportunity for a motivated Scientist to join a company on the ground floor. We aim to produce the best quality UPS protein reagents, assays, and custom services. Your contributions will have an immediate impact. We are seeking collaborative, relentless problem solvers who share our passion for making an impact. Responsibilities
The Product Scientist is a proven protein scientist with expertise in in vitro assay development and the design and production of highly active recombinant proteins. He/she will have expertise in a wide range of protein biochemistry, molecular biology, and assay techniques and workflows. Design, develop and optimize robust, in vitro ubiquitylation, deubiquitylation and proximity assays using Alpha, HTRF, FP, luminescence, spectral shift and other techniques. Implement quality control standards for assay performance, including dynamic range, limit of detection, precision and linearity. Execute screening campaigns for clients, including sample preparation, reagent handling, and assay execution. Validate assay performance through quality control parameters. Analyze and interpret experimental data and prepare detailed reports and documentation. Design and produce multi-component assay kits for retail distribution, including all required reagents, detailed protocols and example dataset. Provide technical expertise and support to customers to facilitate the successful use of assay kits. Assist in the development and optimization of recombinant protein production processes to ensure successful product launch. Collaborate with production team to validate manufacturing protocols, troubleshoot issues, and ensure product quality and consistency. Support new product launch and product release cycle. Collaborate with sales and marketing teams to ensure scientific accuracy of product descriptions. Prepare webinars, abstracts and present posters at scientific meetings. Maintain up-to-date knowledge of product offerings and scientific developments relevant to customer applications. Stay abreast of the latest advancements in UPS and TPD fields by regularly reviewing scientific literature and publications. Seek advice from subject matter experts to enhance knowledge, inform decision-making, and ensure the application of cutting-edge scientific approaches in designing and executing in vitro assays/applications. Generate detailed datasheets for new reagents including product description, usage statements, quality-control data and references. Provide technical support to customers and resolve any technical issues. All other duties as assigned Required Skills and Experience
PhD in a scientific field (Biochemistry, Protein Chemistry) or related discipline, with 2-5 years of post-doctoral work. Expertise in design and implementation of in vitro enzymatic and proximity assays amenable to medium-to-high throughput screening campaigns (FP, HTRF, SPR, Alpha, etc). Experience writing, editing, and creating various types of long- and short-form content including but no limited too application notes, test cases, customer facing content. Strong written, verbal, analytical, research, and communication skills. Experience with liquid handling and laboratory automation, including dataset management a plus. A resourceful problem solver with the ability to manage multiple ongoing projects and meet deadlines. Meticulous attention to detail. Interest in building a deep understanding of technical platforms, and the ability to translate that knowledge into relevant and valuable content This is a full-time, on-site role. Equal Opportunity
Trilogie Bioscience, Inc. is an Equal Opportunity employer and does not discriminate against an applicant or employee because of race, creed, color, religion, sex, national origin, ancestry, age, sexual orientation, physical or mental disability, or veteran status. Additional Information
Seniority level: Mid-Senior level Employment type: Full-time Job function: Research, Analyst, and Information Technology
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