Inside Higher Ed
Senior Research Scientist, Georgia Cancer Center
Inside Higher Ed, Augusta, Georgia, United States, 30910
Overview
Senior Research Scientist, Georgia Cancer Center – Augusta University. The Georgia Cancer Center (GCC) at Augusta University is seeking a highly motivated faculty member with a deep immunology background to join the CAR-T Cell Therapy discovery research program. The role focuses on design, development, optimization, and nomination of CAR-T cell candidates using in vitro and in vivo assays, working with cross-functional teams to advance lead CAR-T candidates toward clinical application. This position is not on tenure track. Responsibilities
Research – 50%: Independently plan, execute, analyze, and report experiments to support preclinical development of novel T cell therapy products; genome editing and culture of human pluripotent stem cells; perform in vitro cell-based functional assays (cytotoxicity, cytokine production, proliferation, etc.) for CAR-T candidate selection; design, execute, and analyze flow cytometry experiments for CAR-T product characterization. Reporting Research – 50%: Support engineered T cell production activities (gene editing, T cell culture, cryopreservation, cell thawing); culture engineered primary T cells and suspension/adherent cell lines; support IND-enabling preclinical studies; coordinate tasks across projects and teams with prioritization and planning. Required Qualifications
PhD or equivalent in Cell or Molecular Biology/Biological Sciences with 10+ years of research experience. Extensive hands-on experience with Molecular Biology (PCR, qRT-PCR, ddPCR, DNA/RNA and protein preparation), cloning, mammalian cell culture and transfection. Experience with multi-color flow cytometry, panel design, and data analysis. Willingness to accept responsibilities outside of initial job description. Preferred Qualifications
Experience with human CAR-T cell engineering. Experience with viral (lentiviral, retroviral or AAV) and/or non-viral gene delivery methods (e.g., CRISPR-mediated knock-in or targeted genome integration). Experience with immunological assays (cytokine/chemokine analysis such as ELISA or Luminex), cytotoxicity and in vitro cell-based assays with live cell analysis. Proficiency in data analysis tools such as FlowJo and GraphPad Prism. Understanding of US FDA cGMP and international regulatory requirements is welcomed. Shift/Salary/Benefits
This position is fiscal year-based and works year-round. The intended work commitment is 1.0 FTE and is considered full-time. Salary and compensation are commensurate with education, experience, and achievements, and subject to fund availability. Comprehensive benefits include medical, dental, vision, 13 paid holidays, vacation leave, sick leave, retirement plans, tuition waiver, wellness options, and more. Eligible full-time employees with more than 6 months of service may be considered for the Tuition Assistance Program. Rank and salary are determined at hire based on experience, education, credentials, specialty, training, etc., while considering internal equity and market data. Advancement through the Augusta University faculty ranks occurs via the Annual Promotion and Tenure process (typically every five years). For more information, please review the Augusta University Promotion and Tenure website. Location/Conditions of Employment
Location: Our Health Sciences Campus, 1120 15th Street, Augusta, GA 30912. All selected candidates must pass a background check prior to starting. Depending on duties, a credit check may be required for Positions of Trust or approved departmental Purchase Card usage. Motor vehicle reports may be required for driving Augusta University vehicles. For faculty hires, official transcripts or educational/credential evaluations may be requested for foreign-trained candidates. All employees must adhere to cybersecurity and privacy policies. Equal Employment Opportunity
Augusta University is an equal opportunity employer welcoming applicants from underrepresented groups, including individuals with disabilities and veterans. How To Apply
To apply, please submit online at the Augusta University careers portal. Upload your Curriculum Vitae, Research Statement, and Professional References as a single document. Other Information
Augusta University is a tobacco-free environment. A brief note on equal opportunity and internal policies is included as part of the job posting. For reference, the original posting can be viewed at the Augusta University jobs portal with Job ID 276341.
#J-18808-Ljbffr
Senior Research Scientist, Georgia Cancer Center – Augusta University. The Georgia Cancer Center (GCC) at Augusta University is seeking a highly motivated faculty member with a deep immunology background to join the CAR-T Cell Therapy discovery research program. The role focuses on design, development, optimization, and nomination of CAR-T cell candidates using in vitro and in vivo assays, working with cross-functional teams to advance lead CAR-T candidates toward clinical application. This position is not on tenure track. Responsibilities
Research – 50%: Independently plan, execute, analyze, and report experiments to support preclinical development of novel T cell therapy products; genome editing and culture of human pluripotent stem cells; perform in vitro cell-based functional assays (cytotoxicity, cytokine production, proliferation, etc.) for CAR-T candidate selection; design, execute, and analyze flow cytometry experiments for CAR-T product characterization. Reporting Research – 50%: Support engineered T cell production activities (gene editing, T cell culture, cryopreservation, cell thawing); culture engineered primary T cells and suspension/adherent cell lines; support IND-enabling preclinical studies; coordinate tasks across projects and teams with prioritization and planning. Required Qualifications
PhD or equivalent in Cell or Molecular Biology/Biological Sciences with 10+ years of research experience. Extensive hands-on experience with Molecular Biology (PCR, qRT-PCR, ddPCR, DNA/RNA and protein preparation), cloning, mammalian cell culture and transfection. Experience with multi-color flow cytometry, panel design, and data analysis. Willingness to accept responsibilities outside of initial job description. Preferred Qualifications
Experience with human CAR-T cell engineering. Experience with viral (lentiviral, retroviral or AAV) and/or non-viral gene delivery methods (e.g., CRISPR-mediated knock-in or targeted genome integration). Experience with immunological assays (cytokine/chemokine analysis such as ELISA or Luminex), cytotoxicity and in vitro cell-based assays with live cell analysis. Proficiency in data analysis tools such as FlowJo and GraphPad Prism. Understanding of US FDA cGMP and international regulatory requirements is welcomed. Shift/Salary/Benefits
This position is fiscal year-based and works year-round. The intended work commitment is 1.0 FTE and is considered full-time. Salary and compensation are commensurate with education, experience, and achievements, and subject to fund availability. Comprehensive benefits include medical, dental, vision, 13 paid holidays, vacation leave, sick leave, retirement plans, tuition waiver, wellness options, and more. Eligible full-time employees with more than 6 months of service may be considered for the Tuition Assistance Program. Rank and salary are determined at hire based on experience, education, credentials, specialty, training, etc., while considering internal equity and market data. Advancement through the Augusta University faculty ranks occurs via the Annual Promotion and Tenure process (typically every five years). For more information, please review the Augusta University Promotion and Tenure website. Location/Conditions of Employment
Location: Our Health Sciences Campus, 1120 15th Street, Augusta, GA 30912. All selected candidates must pass a background check prior to starting. Depending on duties, a credit check may be required for Positions of Trust or approved departmental Purchase Card usage. Motor vehicle reports may be required for driving Augusta University vehicles. For faculty hires, official transcripts or educational/credential evaluations may be requested for foreign-trained candidates. All employees must adhere to cybersecurity and privacy policies. Equal Employment Opportunity
Augusta University is an equal opportunity employer welcoming applicants from underrepresented groups, including individuals with disabilities and veterans. How To Apply
To apply, please submit online at the Augusta University careers portal. Upload your Curriculum Vitae, Research Statement, and Professional References as a single document. Other Information
Augusta University is a tobacco-free environment. A brief note on equal opportunity and internal policies is included as part of the job posting. For reference, the original posting can be viewed at the Augusta University jobs portal with Job ID 276341.
#J-18808-Ljbffr