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Gameto

Scientist II

Gameto, New York, New York, us, 10261

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Job Title: Scientist II- Cell Engineering Location:

New York City, USA Compensation Range:

$100,000-$120,000 We are seeking an

experienced, highly motivated Scientist II

to join our innovative team at Gameto. This is a unique opportunity to lead cutting-edge research at the intersection of

cell biology, biotechnology, and women’s health , contributing directly to the development of

novel cell therapies for menopause . Our mission is to

transform the future of endocrine care for women

by advancing therapeutic solutions that make a meaningful impact. If you are passionate about scientific discovery, thrive in dynamic environments, and possess

advanced expertise in pluripotent stem cell culture and differentiation , this role offers a platform for you to

drive innovation in translational research . About the Role Gameto is pioneering next-generation cell therapies for reproductive health. We are seeking a

highly motivated and technically skilled Cell Engineer

with deep experience in

pluripotent stem cell manipulation, gene editing , and

directed differentiation

to join our growing research team. The ideal candidate will have a strong PhD foundation and 0–2 years of postdoctoral or industry experience engineering stem cells, including transcription factor-mediated lineage specification, molecular cloning, and molecular analysis. This is an exciting opportunity to shape the future of cell therapy and regenerative medicine with a talented, mission-driven team. Key Responsibilities Lead and execute

experimental plans for engineering and differentiating human iPSCs (hiPSCs) toward reproductive cell fates or other target lineages. Design and perform gene editing

using transposon-based editing or related systems to engineer reporter lines or modulate gene function. Implement

transcription factor-mediated differentiation

protocols and systematically optimize lineage commitment. Apply

molecular cloning

strategies for construct generation and cell engineering workflows. Develop and validate

high-throughput functional screening

approaches to assess differentiation efficiency and phenotype. Analyze and interpret complex multi-modal datasets (e.g., RNA-seq, qPCR, flow cytometry, ELISA, viability assays) to guide iteration. Contribute to the development of

3D cell culture , organoid models, or encapsulation systems for in vitro evaluation. Collaborate across cell biology, biomaterials, and bioinformatics teams to align strategies with company milestones. Prepare and present data at internal reviews, external partnerships, and scientific conferences. Maintain accurate, detailed electronic lab notebooks and adhere to rigorous scientific and safety standards. Required Qualifications Ph.D. in Cell Biology, Molecular Biology, Biomedical Engineering, Genetics, or related field. 0–2+ years of relevant postdoctoral or industry experience in a cell engineering or stem cell lab. Proven expertise with

hiPSC maintenance, genetic modification, and differentiation protocols . Strong molecular biology toolkit, including

CRISPR/Cas9/Transposon/Lentivirus editing, cloning, and construct design . Experience with

transcription factor-based programming

or directed lineage specification. Hands-on proficiency in

functional assays , ELISA, RNA-seq, and single-cell analysis techniques. Strong familiarity with

3D cell culture , organoids, microfluidics, or encapsulation systems is a plus. Excellent problem-solving skills and ability to work independently while contributing to collaborative goals. Strong communication and data presentation skills. Detail-oriented and organized, with a commitment to high-quality lab practice. How to Apply If you are excited about advancing women’s health through cutting-edge science and want to be part of a mission-driven team, we encourage you to apply today! Please apply on LinkedIn and with the following materials together in a single PDF document: A cover letter that: Highlights your experience in bioinformatics and relevance to this role Shares your interest in Gameto and anticipated start date Provides any other information you’d like us to consider CV/resume Why Join Us? At Gameto, you’ll have the chance to work alongside top scientists and engineers at the intersection of cell biology, computational science, and women’s health. As a Bioinformatics Scientist, your insights will shape the development, quality, and impact of novel therapies. Your work will contribute directly to advancing women’s health through innovation and precision. About Gameto Gameto is a pioneering biotechnology company in women’s health, co-founded by Dina Radenkovic, a physician-turned-entrepreneur, and Martin Varsavsky, a leader in fertility innovation and founder of the Prelude Network. With our groundbreaking cell engineering platform—developed through a collaboration with Harvard University’s Wyss Institute and Professor George Church’s lab at Harvard Medical School—we aim to create treatments for menopause and infertility affecting the female reproductive system. Our scientific approach surpasses traditional therapeutic modalities and sets a new gold standard for research and development in the field. Backed by $73 million raised in Series A and B funding from Insight Partners, Future Ventures, RA Capital, Two Sigma Ventures, Lux Capital, and others as well as $10 million from ARPA-H, Gameto is committed to transforming women’s healthcare through bold innovation. Read about us in: MIT Technology Review, The New Yorker, The Boston Globe, and Stat News. Our Values and Commitment to Diversity At Gameto, we value kindness, collaboration, authenticity, and diversity. We are an equal opportunity employer and are committed to creating an inclusive environment. We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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