MBC BioLabs
Research Assistant II Therna Biosciences RNA Design. By Intelligence.
MBC BioLabs, San Francisco, California, United States, 94199
Overview
We are looking for a creative, driven, and collaborative Research Associate to join our R&D team. This role offers the opportunity to work on cutting-edge RNA technologies and contribute to the development of high-throughput discovery platforms. The ideal candidate brings strong molecular biology skills and a passion for innovation in RNA therapeutics. Reports to: Director of Translational Research
Responsibilities
Perform molecular and cell biology experiments in support of platform discovery efforts.
Assist in the design, execution, and troubleshooting of experiments involving genomics tools in cell and animal models.
Maintain detailed experimental records and contribute to data analysis and interpretation.
Participate in the management and organization of laboratory supplies and the logistical operations of the lab.
Collaborate closely with team members across functional areas in a fast-paced environment.
Desired experience and skill set
Bachelor’s degree with 3+ years or a Master’s degree with 1+ years of relevant laboratory experience.
Hands-on experience in mammalian cell culture, molecular cloning, in vitro transcription (IVT), flow cytometry, luciferase reporter assay, Immunocytochemistry (ICC), RNAScope, and western blot.
Animal handling experience including injections, blood collection, and tissue processing including IVIS imaging desired.
Experience with Massively Parallel Reporter Assays (MPRAs), using either reporter expression or NGS as readout desired.
Familiarity with single-cell RNA sequencing workflows (e.g., 10x Genomics), including sample prep and library generation.
Exposure to CRISPR-based functional genomics screens is a plus.
Strong problem-solving skills, attention to detail, and scientific curiosity.
Ability to work both independently and as part of a collaborative, interdisciplinary team.
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Responsibilities
Perform molecular and cell biology experiments in support of platform discovery efforts.
Assist in the design, execution, and troubleshooting of experiments involving genomics tools in cell and animal models.
Maintain detailed experimental records and contribute to data analysis and interpretation.
Participate in the management and organization of laboratory supplies and the logistical operations of the lab.
Collaborate closely with team members across functional areas in a fast-paced environment.
Desired experience and skill set
Bachelor’s degree with 3+ years or a Master’s degree with 1+ years of relevant laboratory experience.
Hands-on experience in mammalian cell culture, molecular cloning, in vitro transcription (IVT), flow cytometry, luciferase reporter assay, Immunocytochemistry (ICC), RNAScope, and western blot.
Animal handling experience including injections, blood collection, and tissue processing including IVIS imaging desired.
Experience with Massively Parallel Reporter Assays (MPRAs), using either reporter expression or NGS as readout desired.
Familiarity with single-cell RNA sequencing workflows (e.g., 10x Genomics), including sample prep and library generation.
Exposure to CRISPR-based functional genomics screens is a plus.
Strong problem-solving skills, attention to detail, and scientific curiosity.
Ability to work both independently and as part of a collaborative, interdisciplinary team.
#J-18808-Ljbffr