Logo
Johnson & Johnson

Senior Scientist, Chemical Research

Johnson & Johnson, San Diego, California, United States, 92189

Save Job

Overview

Johnson & Johnson Innovative Medicines is recruiting for a Senior Scientist, Chemical Research located in San Diego, CA. Our work focuses on RNA Therapeutics and Delivery within Cell & Genetic Medicines, driving high-quality drug candidates in the oligonucleotide space. We seek collaborative, growth-oriented scientists to advance science across oligonucleotide chemistry, bioconjugation chemistry, nanotechnology, cellular and molecular pharmacology, and screening technologies. At Johnson & Johnson Innovative Medicine, we pursue promising science to help people live full and healthy lives. This role offers growth opportunities within a dynamic, science-driven organization. Job Information

Job Function:

Discovery & Pre-Clinical/Clinical Development Job Sub Function:

Chemical Research Job Category:

Scientific/Technology All Job Posting Locations:

San Diego, California, United States of America Location note:

This role is based in San Diego, CA. Responsibilities

Independently perform solid phase synthesis, purification, and analysis of oligonucleotides and bioconjugates in a team environment.

Support and troubleshoot process development efforts for synthesis and characterization of oligonucleotides and their bioconjugates.

Collaborate to support oligonucleotide innovation, optimization and design for de-risked, tissue-specific delivery.

Collect, document and evaluate experimental data and communicate scientific findings as verbal presentations and written reports.

Experience and Skills

PhD or equivalent experience in organic/analytical chemistry, chemical biology, or related field with 1 year of industry or academic experience in oligonucleotide drug discovery.

Hands-on experience with siRNA and/or ASO nucleic acid therapeutics development.

Experience in siRNA synthesis, purification, and analytical characterization.

Experience in siRNA design and chemical modifications.

Exposure to the oligonucleotide delivery and drug discovery process.

Critical thinking and scientific skills with ability to interpret and clearly communicate data.

Strong teamwork skills; able to work effectively in a dynamic, diverse environment.

Ability to adapt to changing priorities and timelines.

Preferred Qualifications

Experience operating instruments and equipment including MerMade and Dr. Oligo synthesizers, as well as HPLC, LC-MS, UV/Vis purification and characterization instrumentation.

Track record of accomplishments in oligonucleotide research (patents, publications, and/or presentations).

Knowledge and experience with oligonucleotide delivery via bioconjugation strategies.

Knowledge of RNA biology and oligonucleotide screening technologies to facilitate effective team collaboration.

Expertise in RNA structure–function studies and molecular modeling; understanding thermodynamic stability of oligonucleotide structures is preferred.

Equal Opportunity and Benefits

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an inclusive interview process. If you are an individual with a disability and would like to request an accommodation, please contact us via https://www.jnj.com/contact-us/careers. Internal employees should follow AskGS for accommodation resources. Compensation and Benefits

The anticipated base pay range for this position is:

$105,000-$169,050 Additional Description for Pay Transparency: Employees may participate in Company-sponsored benefit programs (medical, dental, vision, life insurance, disability, etc.), retirement and savings plans, and time-off benefits. See https://www.careers.jnj.com/employee-benefits for details.

#J-18808-Ljbffr