Johnson and Johnson
Senior Director, R&D Data Science & Digital Health - Ophthalmology
Johnson and Johnson, Cambridge, Massachusetts, us, 02140
Overview
Johnson & Johnson is a global healthcare leader focused on developing medicines, medical devices, and consumer products to advance human health and well-being. Role Summary
We are seeking an experienced Senior Director to lead our data science and digital health strategy for ophthalmology.
This role will shape and execute innovative approaches leveraging mult-omics, digital health technologies, artificial intelligence, and clinical/real‑world evidence (RWE) to accelerate drug discovery, development, and patient impact. Key Responsibilities
Define and execute the data science and digital health strategy for ophthalmology, integrating computational biology, AI/ML, digital health, and clinical/RWE insights. Drive the application of mult-omics (genomics, proteomics, transcriptomics, metabolomics, etc.) and integrative analytics to uncover disease mechanisms, biomarkers, and novel targets. Lead the development, validation, and regulatory engagement of digital tools and novel endpoints to enhance clinical trial design, patient monitoring, and care pathways. Champion the use of machine learning, deep learning, generative and agentic AI to accelerate patient stratification, disease modeling, and translational discovery. Partner with clinical development and medical affairs to integrate RWE into evidence generation, supporting trial optimization, regulatory submissions, and real‑world impact assessment. Build strong cross‑functional and external collaborations with academic groups, technology providers, regulators, and consortia to position the company at the forefront of data‑driven science. Recruit, develop and inspire a diverse team of digital health scientists, RWE experts and computational scientists to deliver on strategic initiatives. Qualifications
Advanced degree (PhD, MD or equivalent) in neuroscience or related quantitative sciences required. 10+ years of relevant industry or academic experience with proven leadership in applying data‑driven methods to drug discovery and development required. 7+ years of people‑management experience required. Experience in clinical development with demonstrated expertise in ophthalmology preferred. Excellent communication skills, with the ability to translate complex data‑driven insights into clear strategies for senior stakeholders and external partners required. Technical Expertise
in at least two of the following areas required: 1) proficiency in mult‑omics integration and advanced statistical/causal inference methods; 2) expertise in applying digital health technologies and novel endpoints in clinical research; 3) experience with large‑scale clinical datasets, EHR, and real‑world data and advanced modeling, longitudinal analysis, and patient stratification. Track record of scientific contributions (presentations and publications) in this field required. Familiarity with data standards, privacy regulations, and regulatory qualification pathways required. Knowledge of data infrastructures and development of data analysis pipelines at scale, and state‑of‑the‑art AI methodologies is a plus. Competence with programming and analytics environments (Python, R) with ability to guide technical teams at a strategic level required. Demonstrated success in leading cross‑disciplinary teams at the interface of data science, biology, and clinical development required. Hybrid schedule: 3 days per week onsite, 2 days remote (no fully remote option available).
May require approximately 25% domestic and international travel. Johnson & Johnson is an Equal Opportunity Employer.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law.
We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Compensation: $193,000 to $333,500 base salary with performance bonus and benefits including medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, group legal insurance, and retirement plan (401(k) and pension). Time off benefits: Vacation up to 120 hours per calendar year; Sick time up to 40 hours per calendar year; Holiday pay, including floating holidays, up to 13 days per calendar year; Work, personal and family time up to 40 hours per calendar year. Additional information can be found at https://www.careers.jnj.com/employee-benefits.
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Johnson & Johnson is a global healthcare leader focused on developing medicines, medical devices, and consumer products to advance human health and well-being. Role Summary
We are seeking an experienced Senior Director to lead our data science and digital health strategy for ophthalmology.
This role will shape and execute innovative approaches leveraging mult-omics, digital health technologies, artificial intelligence, and clinical/real‑world evidence (RWE) to accelerate drug discovery, development, and patient impact. Key Responsibilities
Define and execute the data science and digital health strategy for ophthalmology, integrating computational biology, AI/ML, digital health, and clinical/RWE insights. Drive the application of mult-omics (genomics, proteomics, transcriptomics, metabolomics, etc.) and integrative analytics to uncover disease mechanisms, biomarkers, and novel targets. Lead the development, validation, and regulatory engagement of digital tools and novel endpoints to enhance clinical trial design, patient monitoring, and care pathways. Champion the use of machine learning, deep learning, generative and agentic AI to accelerate patient stratification, disease modeling, and translational discovery. Partner with clinical development and medical affairs to integrate RWE into evidence generation, supporting trial optimization, regulatory submissions, and real‑world impact assessment. Build strong cross‑functional and external collaborations with academic groups, technology providers, regulators, and consortia to position the company at the forefront of data‑driven science. Recruit, develop and inspire a diverse team of digital health scientists, RWE experts and computational scientists to deliver on strategic initiatives. Qualifications
Advanced degree (PhD, MD or equivalent) in neuroscience or related quantitative sciences required. 10+ years of relevant industry or academic experience with proven leadership in applying data‑driven methods to drug discovery and development required. 7+ years of people‑management experience required. Experience in clinical development with demonstrated expertise in ophthalmology preferred. Excellent communication skills, with the ability to translate complex data‑driven insights into clear strategies for senior stakeholders and external partners required. Technical Expertise
in at least two of the following areas required: 1) proficiency in mult‑omics integration and advanced statistical/causal inference methods; 2) expertise in applying digital health technologies and novel endpoints in clinical research; 3) experience with large‑scale clinical datasets, EHR, and real‑world data and advanced modeling, longitudinal analysis, and patient stratification. Track record of scientific contributions (presentations and publications) in this field required. Familiarity with data standards, privacy regulations, and regulatory qualification pathways required. Knowledge of data infrastructures and development of data analysis pipelines at scale, and state‑of‑the‑art AI methodologies is a plus. Competence with programming and analytics environments (Python, R) with ability to guide technical teams at a strategic level required. Demonstrated success in leading cross‑disciplinary teams at the interface of data science, biology, and clinical development required. Hybrid schedule: 3 days per week onsite, 2 days remote (no fully remote option available).
May require approximately 25% domestic and international travel. Johnson & Johnson is an Equal Opportunity Employer.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law.
We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Compensation: $193,000 to $333,500 base salary with performance bonus and benefits including medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, group legal insurance, and retirement plan (401(k) and pension). Time off benefits: Vacation up to 120 hours per calendar year; Sick time up to 40 hours per calendar year; Holiday pay, including floating holidays, up to 13 days per calendar year; Work, personal and family time up to 40 hours per calendar year. Additional information can be found at https://www.careers.jnj.com/employee-benefits.
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