Legend Biotech
Legend Biotech – Analyst II, Scientific Development
Legend Biotech is a global biotechnology company dedicated to treating life‑threatening diseases. Our cell therapy platform spans autologous and allogenic chimeric antigen receptor T‑cell, T‑cell receptor (TCR‑T), and natural killer (NK) cell–based immunotherapies.
Role Overview We are seeking a dynamic Scientist II to join our Flow Cytometry and Functional Assays team within Analytical Development. The role focuses on establishing, developing, and qualifying flow cytometry–based methods, cell‑based potency assays, and other bioanalytical strategies to support product release, characterization, and stability assessment of cell therapy products.
Key Responsibilities
Develop and optimize potency, flow cytometry, and ELISA–based assays.
Tech‑transfer methods to QC, perform assay pre‑qualification and qualification, refine critical parameters, and generate cell banks.
Generate SOPs and laboratory protocols for product release testing and characterization.
Collaborate cross‑functionally with QC and Manufacturing teams to ensure seamless assay execution, troubleshooting, and continuous improvement.
Present scientific data and trends at internal and external forums.
Maintain proper ELN, test method development plan, report, equipment maintenance logs, and laboratory inventories.
Simultaneously manage multiple projects to meet timelines while upholding data integrity and quality standards.
Make decisions related to assay development runs and weekly work priorities within the scope of the role.
Requirements
PhD or Master’s in a scientific discipline with 2–5 years of related experience, may include post‑doctoral experience.
Expert knowledge of analytical method development, qualification, and validation.
Experience developing multicolor flow cytometry methods, cell culture, potency assays, cytotoxicity assays, cytokine release assays, immunoassays, and infectious titer assays.
Ability to exercise independent judgment in developing methods, techniques, and evaluation criteria.
Solid understanding of ICH guidelines and regulatory expectations for method qualification.
Guide the establishment and authorship of SOPs for established methods.
Detail‑oriented with strong problem‑solving and decision‑making skills.
Excellent presentation, scientific/technical writing, Excel, Word, PowerPoint skills.
Experience with GraphPad Prism, FlowJo, ELN tools such as LabVantage.
Compensation Base pay range: $107,482 – $141,070 USD.
Benefits
Medical, dental, vision insurance.
401(k) retirement plan with company match.
Equity and stock options.
Paid parental leave (8 weeks).
Paid time off: 15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, 3 floating holidays.
Flexible spending accounts, health savings accounts.
Life, AD&D, short‑term and long‑term disability coverage.
Legal assistance, supplemental plans (pet, critical illness, accident, hospital indemnity).
Commuter benefits, family planning and care resources, well‑being initiatives.
EEO Statement Legend Biotech is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. Employment is at‑will, may be terminated without cause or notice, and is subject to standard drug‑free workplace policies.
Location: Somerset, New Jersey.
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Role Overview We are seeking a dynamic Scientist II to join our Flow Cytometry and Functional Assays team within Analytical Development. The role focuses on establishing, developing, and qualifying flow cytometry–based methods, cell‑based potency assays, and other bioanalytical strategies to support product release, characterization, and stability assessment of cell therapy products.
Key Responsibilities
Develop and optimize potency, flow cytometry, and ELISA–based assays.
Tech‑transfer methods to QC, perform assay pre‑qualification and qualification, refine critical parameters, and generate cell banks.
Generate SOPs and laboratory protocols for product release testing and characterization.
Collaborate cross‑functionally with QC and Manufacturing teams to ensure seamless assay execution, troubleshooting, and continuous improvement.
Present scientific data and trends at internal and external forums.
Maintain proper ELN, test method development plan, report, equipment maintenance logs, and laboratory inventories.
Simultaneously manage multiple projects to meet timelines while upholding data integrity and quality standards.
Make decisions related to assay development runs and weekly work priorities within the scope of the role.
Requirements
PhD or Master’s in a scientific discipline with 2–5 years of related experience, may include post‑doctoral experience.
Expert knowledge of analytical method development, qualification, and validation.
Experience developing multicolor flow cytometry methods, cell culture, potency assays, cytotoxicity assays, cytokine release assays, immunoassays, and infectious titer assays.
Ability to exercise independent judgment in developing methods, techniques, and evaluation criteria.
Solid understanding of ICH guidelines and regulatory expectations for method qualification.
Guide the establishment and authorship of SOPs for established methods.
Detail‑oriented with strong problem‑solving and decision‑making skills.
Excellent presentation, scientific/technical writing, Excel, Word, PowerPoint skills.
Experience with GraphPad Prism, FlowJo, ELN tools such as LabVantage.
Compensation Base pay range: $107,482 – $141,070 USD.
Benefits
Medical, dental, vision insurance.
401(k) retirement plan with company match.
Equity and stock options.
Paid parental leave (8 weeks).
Paid time off: 15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, 3 floating holidays.
Flexible spending accounts, health savings accounts.
Life, AD&D, short‑term and long‑term disability coverage.
Legal assistance, supplemental plans (pet, critical illness, accident, hospital indemnity).
Commuter benefits, family planning and care resources, well‑being initiatives.
EEO Statement Legend Biotech is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. Employment is at‑will, may be terminated without cause or notice, and is subject to standard drug‑free workplace policies.
Location: Somerset, New Jersey.
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