Chan Zuckerberg Biohub Network
Postdoctoral Fellow, Molecular Biology (Proteoform Spatial Biology Group - Biohu
Chan Zuckerberg Biohub Network, Chicago, Illinois, United States, 60290
Postdoctoral Fellow, Molecular Biology (Proteoform Spatial Biology Group – Biohub Chicago)
The Chan Zuckerberg Biohub Chicago is an independent nonprofit research institute that combines three leading universities—Northwestern, University of Chicago, and University of Illinois Urbana-Champaign—into a single collaborative technology and discovery engine. CZ Biohub supports bold engineers, data scientists, and biomedical researchers to innovate in medicine and develop new technologies. CZ Biohub Chicago’s values emphasize scholarly excellence, disruptive innovation, hands‑on engineering, partnership, open communication, inclusiveness, and opportunity for all.
Opportunity We are seeking an outstanding early‑career scientist to join and contribute to the launch of the Proteoform Spatial Biology Group. The role is a Postdoctoral Fellow in Molecular Biology focused on uncovering the spatiotemporal regulation of proteins and their unique molecular forms (proteoforms) in inflammation and autoimmunity. The ideal candidate has experience working with primary human cell cultures and single‑cell nucleic acid sequencing–based assays.
Responsibilities
Culture, stimulate, and analyze human T‑cells from primary sources and immortalized cell lines.
Design and execute cutting‑edge spatial proteomic studies of inflammation and immune dysregulation using nucleic acid sequencing–based techniques.
Analyze and interpret results, contributing to collaborative datasets, manuscripts, and analyses.
Present findings internally and externally.
Co‑author publications.
Qualifications (Essential)
PhD in molecular biology, immunology, bioengineering, or a related field.
Hands‑on experience culturing and manipulating primary human T‑cells and immune cell lines.
Proficiency with cytokine stimulation and immune functional assays.
Strong experimental design and troubleshooting skills.
Experience with nucleic acid sequencing–based assays (e.g., molecular barcoding, library preparation for single‑cell RNA sequencing).
Ability to plan, execute, and troubleshoot complex experiments.
Ability to work collaboratively and independently.
Nice to Have
Familiarity with single‑cell technologies.
Data analysis skills in R or Python.
Experience coordinating cross‑lab collaborations.
Experience in protein engineering or site‑directed mutagenesis.
Experience with mass spectrometry and/or imaging‑based proteomics.
Compensation and Benefits The Chicago base pay range is $84,150.00. Benefits include a generous 401(k) match, paid volunteer time off, funding for select family‑forming benefits, and relocation support for employees who need assistance moving.
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Opportunity We are seeking an outstanding early‑career scientist to join and contribute to the launch of the Proteoform Spatial Biology Group. The role is a Postdoctoral Fellow in Molecular Biology focused on uncovering the spatiotemporal regulation of proteins and their unique molecular forms (proteoforms) in inflammation and autoimmunity. The ideal candidate has experience working with primary human cell cultures and single‑cell nucleic acid sequencing–based assays.
Responsibilities
Culture, stimulate, and analyze human T‑cells from primary sources and immortalized cell lines.
Design and execute cutting‑edge spatial proteomic studies of inflammation and immune dysregulation using nucleic acid sequencing–based techniques.
Analyze and interpret results, contributing to collaborative datasets, manuscripts, and analyses.
Present findings internally and externally.
Co‑author publications.
Qualifications (Essential)
PhD in molecular biology, immunology, bioengineering, or a related field.
Hands‑on experience culturing and manipulating primary human T‑cells and immune cell lines.
Proficiency with cytokine stimulation and immune functional assays.
Strong experimental design and troubleshooting skills.
Experience with nucleic acid sequencing–based assays (e.g., molecular barcoding, library preparation for single‑cell RNA sequencing).
Ability to plan, execute, and troubleshoot complex experiments.
Ability to work collaboratively and independently.
Nice to Have
Familiarity with single‑cell technologies.
Data analysis skills in R or Python.
Experience coordinating cross‑lab collaborations.
Experience in protein engineering or site‑directed mutagenesis.
Experience with mass spectrometry and/or imaging‑based proteomics.
Compensation and Benefits The Chicago base pay range is $84,150.00. Benefits include a generous 401(k) match, paid volunteer time off, funding for select family‑forming benefits, and relocation support for employees who need assistance moving.
#J-18808-Ljbffr