BioSpace
Postdoctoral Scientist - Antibody-RNA Conjugation, Genetic Medicine
BioSpace, Boston, Massachusetts, us, 02298
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees work to discover and bring life‑changing medicines to those who need them, improve the understanding and management of disease, and give back through philanthropy and volunteerism.
Responsibilities
Develop novel linker strategies for antibody‑RNA conjugates and bioconjugation methodologies.
Design and synthesize novel linkers for controlled drug release.
Collaborate closely with ADME teams to develop robust bioanalytical methods and investigate PK/PD relationships for antibody‑RNA conjugates.
Contribute to optimization of internal antibody‑RNA conjugate workflow.
Work productively and safely in the laboratory; maintain good practice in writing experimental reports in an electronic lab notebook.
Communicate experimental results and project progress with supervisor and at team/department meetings.
Publish/share original research externally (presentations, peer‑reviewed articles, and conferences).
Qualifications
Ph.D. in synthetic chemistry, chemical biology, or related scientific field.
Additional Skills
Extensive knowledge of cutting‑edge modern organic chemistry, linker design and complex molecule synthesis.
Understanding advanced analytical and purification techniques.
Experience in antibody‑drug conjugates and/or oligonucleotide chemistry will be preferred.
Proficiency in independently executing research tasks.
High learning agility in the field of new scientific concepts and drug modalities.
Strong problem‑solving skills with creative solutions in constructing complex molecular systems.
A proven track record of significant contributions to research projects, substantiated by first or co‑authorship on peer‑reviewed scientific publications.
A track record of productive collaborations in interdisciplinary team environment.
Excellent communication and organizational skills.
We are dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
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Responsibilities
Develop novel linker strategies for antibody‑RNA conjugates and bioconjugation methodologies.
Design and synthesize novel linkers for controlled drug release.
Collaborate closely with ADME teams to develop robust bioanalytical methods and investigate PK/PD relationships for antibody‑RNA conjugates.
Contribute to optimization of internal antibody‑RNA conjugate workflow.
Work productively and safely in the laboratory; maintain good practice in writing experimental reports in an electronic lab notebook.
Communicate experimental results and project progress with supervisor and at team/department meetings.
Publish/share original research externally (presentations, peer‑reviewed articles, and conferences).
Qualifications
Ph.D. in synthetic chemistry, chemical biology, or related scientific field.
Additional Skills
Extensive knowledge of cutting‑edge modern organic chemistry, linker design and complex molecule synthesis.
Understanding advanced analytical and purification techniques.
Experience in antibody‑drug conjugates and/or oligonucleotide chemistry will be preferred.
Proficiency in independently executing research tasks.
High learning agility in the field of new scientific concepts and drug modalities.
Strong problem‑solving skills with creative solutions in constructing complex molecular systems.
A proven track record of significant contributions to research projects, substantiated by first or co‑authorship on peer‑reviewed scientific publications.
A track record of productive collaborations in interdisciplinary team environment.
Excellent communication and organizational skills.
We are dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
#J-18808-Ljbffr