Virginia Tech
Computational Biology Postdoc Positions
Virginia Tech, Washington, District of Columbia, us, 20022
Postdoctoral Researcher – Tumor Microenvironment
Dr. Shenglin Mei lab at Fralin Biomedical Research Institute (FBRI) Cancer Research Center DC and Children’s National Center for Cancer and Immunology Research is seeking highly motivated postdoctoral fellows and graduate students to join our team. The lab studies the remodeling and regulatory mechanisms of the tumor microenvironment during tumor progression and metastasis. The lab specializes in computational biology and combines single-cell technologies, genomic datasets, machine learning, and experimental methods to investigate how the tumor microenvironment and gene regulatory factors control tumor metastasis cascade. By advancing our understanding of malignant cell heterogeneity and context-dependent tumor microenvironment remodeling, we aim to drive the development of novel therapeutic approaches for patients with metastatic cancer. Research Focus
The current directions in the lab include the following: Investigating context-dependent remodeling of the tumor microenvironment. Identifying novel regulators within the tumor microenvironment. Developing computational methods for integrating multimodal data, such as scRNA‑seq, scATAC‑seq, spatial transcriptomics, ChIP‑seq, and CRISPR screening. Exploring tumor organ-specific metastasis with multi‑omics data integration. Candidate Responsibilities
The candidate will develop novel statistical and machine learning methods for multi‑omics data integration and apply the computational methods to explore the dysregulation and regulation of tumor microenvironment, malignant cell heterogeneity, plasticity, and tumor immunology. Preferred Qualifications
PhD and/or MD in computational biology, bioinformatics, genomics, biology, data science, computer science, or other related fields. Experience in high-throughput sequencing data analysis, knowledge in supervised and unsupervised machine learning, or deep learning models. Strong programming skills in Python or R, and Linux Shell; experience in genomics data processing and open source repositories, e.g., GitHub is a plus. Track record of first/co-first-author original research papers. Strong oral and written communication skills. How to Apply
Interested applicants should submit the following materials via email to Dr. Shenglin Mei (shenglinmei@vtc.vt.edu): 1) a cover letter describing current research activities and your interest in this position, 2) a current CV (including publications), and 3) contact information for three references. About Virginia Tech and Children’s National Hospital
Virginia Tech, founded in 1872, is one of the top public universities in the United States. According to the latest U.S. News national university rankings, Virginia Tech ranks 47th overall for national universities and 20th among public universities. Children’s National Hospital, based in Washington, D.C., has been serving the nation’s children since 1870. Children’s National is #6 overall, #1 for babies, and ranked in every specialty evaluated by U.S. News & World Report for children’s hospital in the U.S. Children’s National is recognized for its expertise and innovation in pediatric care and as a strong voice for children through advocacy at the local, regional and national levels.
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Dr. Shenglin Mei lab at Fralin Biomedical Research Institute (FBRI) Cancer Research Center DC and Children’s National Center for Cancer and Immunology Research is seeking highly motivated postdoctoral fellows and graduate students to join our team. The lab studies the remodeling and regulatory mechanisms of the tumor microenvironment during tumor progression and metastasis. The lab specializes in computational biology and combines single-cell technologies, genomic datasets, machine learning, and experimental methods to investigate how the tumor microenvironment and gene regulatory factors control tumor metastasis cascade. By advancing our understanding of malignant cell heterogeneity and context-dependent tumor microenvironment remodeling, we aim to drive the development of novel therapeutic approaches for patients with metastatic cancer. Research Focus
The current directions in the lab include the following: Investigating context-dependent remodeling of the tumor microenvironment. Identifying novel regulators within the tumor microenvironment. Developing computational methods for integrating multimodal data, such as scRNA‑seq, scATAC‑seq, spatial transcriptomics, ChIP‑seq, and CRISPR screening. Exploring tumor organ-specific metastasis with multi‑omics data integration. Candidate Responsibilities
The candidate will develop novel statistical and machine learning methods for multi‑omics data integration and apply the computational methods to explore the dysregulation and regulation of tumor microenvironment, malignant cell heterogeneity, plasticity, and tumor immunology. Preferred Qualifications
PhD and/or MD in computational biology, bioinformatics, genomics, biology, data science, computer science, or other related fields. Experience in high-throughput sequencing data analysis, knowledge in supervised and unsupervised machine learning, or deep learning models. Strong programming skills in Python or R, and Linux Shell; experience in genomics data processing and open source repositories, e.g., GitHub is a plus. Track record of first/co-first-author original research papers. Strong oral and written communication skills. How to Apply
Interested applicants should submit the following materials via email to Dr. Shenglin Mei (shenglinmei@vtc.vt.edu): 1) a cover letter describing current research activities and your interest in this position, 2) a current CV (including publications), and 3) contact information for three references. About Virginia Tech and Children’s National Hospital
Virginia Tech, founded in 1872, is one of the top public universities in the United States. According to the latest U.S. News national university rankings, Virginia Tech ranks 47th overall for national universities and 20th among public universities. Children’s National Hospital, based in Washington, D.C., has been serving the nation’s children since 1870. Children’s National is #6 overall, #1 for babies, and ranked in every specialty evaluated by U.S. News & World Report for children’s hospital in the U.S. Children’s National is recognized for its expertise and innovation in pediatric care and as a strong voice for children through advocacy at the local, regional and national levels.
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