Prellis Biologics
Director/Sr. Director, Oncology
Prellis Biologics, Berkeley, California, United States, 94709
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The Opportunity The heart of Prellis Bio strategy is the combination of novel, cutting edge methods in machine learning, biology at scale and next gen antibody discovery that address key bottlenecks in the drug development pipeline. To accomplish that, we are putting together an incredible team of discovery biologists, computational scientists, and protein scientists who want to make a difference to this important problem. In this leadership role, you will help build the oncology therapeutic area (TA), hire and manage staff. You will report to the CSO and work a hybrid schedule at our headquarters in Berkeley, CA.
Your Primary Responsibilities Will Include
Contribute to Prellis Bio strategy in oncology addressable by large molecule or complex modalities
Work cross-functionally as a project team lead to design, experiments, high-throughput experimental assays and machine learning models to help deconvolute these biologies
Support identification and validation of high-value, disease-modifying therapeutic targets through literature-based evaluations
Lead efforts and partner with our statistical genetics and machine learning teams to follow up on these targets with the goal of producing viable therapeutic interventions
Move with the project as it moves into the clinic and provide clinical support and work closely with our clinical groups and chief medical officer
Lead external collaborations with partners and other organizations and individuals in efforts related to the oncology area
About You
PhD in oncology with 10 years of experience in target/drug discovery in industry or academia.
A scientific track record in oncology disease with a focus on large molecule (e.g. antibody) modalities
Familiarity with interpreting RNA-seq and protein expression data, translational and preclinical in vitro and in vivo data, and clinical trial results
Demonstrated track record in building partnerships or collaborations with data scientists or computational biologist, engineers and experimental biologists
Experience in basic research, translational biology and supporting immuno-oncology and/or ADC clinical development
Contribution to the preparation of patents, documentation for IND filings, and publications.
Experience leading a high-performance team, including goal setting, and contributing to a culture of high-quality methods development and reducing those methods to a practical implementation
Communicate effectively and collaborate with people of diverse backgrounds and job functions, including a track record of collaborating with life scientists
Passion for making a difference in the world
About Prellis Biologics At Prellis we integrate human biology with machine learning. We aim to revolutionized drug discovery by harnessing the power of human immune system with tightly, integrated machine learning to develop next-generation antibody therapeutics with unparalleled speed, precision and safety. We are committed to empowering our pharmaceutical partners with access to the most promising fully human body candidate rapidly identified from the human immune repertoire, enabling them to bring life-changing treatments to patients faster than ever before. Prellis Biologics is a pre-IPO biotech located in Berkeley CA with a team-oriented, inclusive, and family-friendly culture. Our growing pipeline target high unmet patient needs across therapeutics including metabolic, inflammation, and oncology disease. Prellis has raised funding from top investors, including Celesta, Khosla Ventures, SOSV, & Avidity Partners.
What You Can Expect Of Us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
Benefits
A competitive employee benefits package, including group medical, dental and vision coverage, life and disability insurance, flexible spending accounts and a 401(k) plan
Stock-based long term incentives
Bonus plan
Holiday package including a 1+ week winter shutdown
Flexible work models, including remote and hybrid working arrangements, where possible
Application deadline Prellis does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Prellis Bio is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth‑oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.
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Referrals increase your chances of interviewing at Prellis Biologics by 2x
Get notified about new Oncology Director jobs in
Berkeley, CA .
The Opportunity The heart of Prellis Bio strategy is the combination of novel, cutting edge methods in machine learning, biology at scale and next gen antibody discovery that address key bottlenecks in the drug development pipeline. To accomplish that, we are putting together an incredible team of discovery biologists, computational scientists, and protein scientists who want to make a difference to this important problem. In this leadership role, you will help build the oncology therapeutic area (TA), hire and manage staff. You will report to the CSO and work a hybrid schedule at our headquarters in Berkeley, CA.
Your Primary Responsibilities Will Include
Contribute to Prellis Bio strategy in oncology addressable by large molecule or complex modalities
Work cross-functionally as a project team lead to design, experiments, high-throughput experimental assays and machine learning models to help deconvolute these biologies
Support identification and validation of high-value, disease-modifying therapeutic targets through literature-based evaluations
Lead efforts and partner with our statistical genetics and machine learning teams to follow up on these targets with the goal of producing viable therapeutic interventions
Move with the project as it moves into the clinic and provide clinical support and work closely with our clinical groups and chief medical officer
Lead external collaborations with partners and other organizations and individuals in efforts related to the oncology area
About You
PhD in oncology with 10 years of experience in target/drug discovery in industry or academia.
A scientific track record in oncology disease with a focus on large molecule (e.g. antibody) modalities
Familiarity with interpreting RNA-seq and protein expression data, translational and preclinical in vitro and in vivo data, and clinical trial results
Demonstrated track record in building partnerships or collaborations with data scientists or computational biologist, engineers and experimental biologists
Experience in basic research, translational biology and supporting immuno-oncology and/or ADC clinical development
Contribution to the preparation of patents, documentation for IND filings, and publications.
Experience leading a high-performance team, including goal setting, and contributing to a culture of high-quality methods development and reducing those methods to a practical implementation
Communicate effectively and collaborate with people of diverse backgrounds and job functions, including a track record of collaborating with life scientists
Passion for making a difference in the world
About Prellis Biologics At Prellis we integrate human biology with machine learning. We aim to revolutionized drug discovery by harnessing the power of human immune system with tightly, integrated machine learning to develop next-generation antibody therapeutics with unparalleled speed, precision and safety. We are committed to empowering our pharmaceutical partners with access to the most promising fully human body candidate rapidly identified from the human immune repertoire, enabling them to bring life-changing treatments to patients faster than ever before. Prellis Biologics is a pre-IPO biotech located in Berkeley CA with a team-oriented, inclusive, and family-friendly culture. Our growing pipeline target high unmet patient needs across therapeutics including metabolic, inflammation, and oncology disease. Prellis has raised funding from top investors, including Celesta, Khosla Ventures, SOSV, & Avidity Partners.
What You Can Expect Of Us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
Benefits
A competitive employee benefits package, including group medical, dental and vision coverage, life and disability insurance, flexible spending accounts and a 401(k) plan
Stock-based long term incentives
Bonus plan
Holiday package including a 1+ week winter shutdown
Flexible work models, including remote and hybrid working arrangements, where possible
Application deadline Prellis does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Prellis Bio is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth‑oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.
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