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Sci.bio Recruiting

Scientist/Senior Scientist, LNP Discovery

Sci.bio Recruiting, Cambridge, Massachusetts, us, 02140

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We are seeking a Scientist/Senior Scientist with expertise in lipid nanoparticle (LNP) formulation and application of LNPs in preclinical models. This role involves designing and characterizing LNPs for in vivo RNA delivery, with hands‑on work in pulmonary delivery studies. It offers the opportunity to contribute across the full spectrum of LNP development, from formulation to in vivo evaluation, within a collaborative and interdisciplinary team. We are looking for curious problem solvers who enjoy fast‑paced projects, working within a team, and are passionate about advancing genetic editing technologies.

Primary Responsibilities

Design and formulate LNPs using microfluidics; characterize using DLS, zeta potential, pKa, and nucleic acid assays.

Execute and support in vivo studies focused on pulmonary delivery of LNP formulations, including intratracheal administration in preclinical models.

Collaborate on study design, execution, data collection, and interpretation.

Support downstream analyses using flow cytometry and molecular biology techniques.

Work cross‑functionally to integrate in vivo findings into delivery platform development.

Present data in written reports and oral presentations.

Qualifications

PhD in Biomedical/Chemical Engineering, Biochemistry, or related field with 0–2 years of relevant experience (or BS+8, MS+6).

Experience with lipid nanoparticle (LNP) formulation, quality control, and characterization techniques.

Hands‑on experience with animal handling, dosing, and tissue collection; intratracheal delivery strongly preferred.

Familiarity with molecular biology techniques (e.g., qPCR, sequencing, mammalian cell culture, flow cytometry).

Strong organizational and critical thinking skills, attention to detail, and ability to work both independently and in a team.

Excellent communication and interpersonal skills for cross‑functional collaboration.

Seniority level

Mid‑Senior level

Employment type

Full‑time

Job function

Research

Cambridge, MA $70,000.00 – $90,000.00 1 month ago

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