Evonik Group.
Senior Scientist/Scientist, Nucleic Acid Delivery
Evonik Group., Cambridge, Massachusetts, us, 02140
Senior Scientist/Scientist, Nucleic Acid Delivery page is loaded## Senior Scientist/Scientist, Nucleic Acid Deliverylocations:
Cambridge, Massachusettstime type:
全职posted on:
今天发布job requisition id:
R35314**我们提供什么**与我们一起探索拥有无限可能性的世界。与我们一起展望未来，协助我们形成创新的解决方案，使我们的世界更具有可持续性，使生活更加健康，更加有活力以及更舒适。在赢创，您有机会与 33，000 名同事一起发展与成长。除了有吸引力的职业道路和高质量的发展方案以外，我们还通过 #SmartWork 提供基于绩效的薪酬、健康促进措施以及混合与灵活的工作模式。参与进来，发挥您的强项，开辟新天地，在我们这里找到适合您的工作。**在这儿您可以直接从我们的员工这里获悉更多关于赢创的信息：**We are looking for a passionate and innovative Scientist in the field of Nucleic Acid Delivery to join our dynamic team at the Cambridge Innovation Satellite, MA. This role focuses on advancing the development of lipid-based formulations for nucleic acid therapeutics. As part of a collaborative and interdisciplinary network of scientists, you will contribute to pioneering solutions that address significant challenges in medicine and ultimately improve patient outcomes.**RESPONSIBILITIES*** Design, develop, and characterize novel non-viral vectors for targeted delivery of nucleic acid-based therapeutics, including lipid nanoparticles and alternative gene delivery systems.* Conduct high-throughput in vitro experiments to evaluate the efficacy and safety of developed formulations in traditional and advanced cell culture models.* Collaborate with cross-functional teams to define project scopes, timelines, and deliverables based on market needs and internal capabilities.* Participate in the identification and evaluation of emerging technologies in nucleic acid delivery and contribute to the strategic direction of research initiatives.* Document research findings and present results to internal stakeholders and at scientific conferences, fostering a culture of innovation within the team.* Mentor junior scientists and technicians, providing guidance and support in their professional development.* Engage with external partners in academia and industry to enhance collaborative efforts and knowledge exchange.**REQUIREMENTS*** Ph.D. or 4+ years (M.Sc.) or 6+ years (B.Sc.) of relevant industry experience in LNP development and drug delivery with strong background in nucleic acid therapeutics and education in related discipline (Pharmaceutical Sciences, Biomedical Engineering, Biochemistry, etc).* Strong theoretical and practical knowledge of lipid-based and polymer-based delivery systems, manufacturing technologies and hands-on experience in nanoparticle characterization techniques (e.g., DLS, zeta potential, ribogreen, pKa, chromatography).* Knowledge of formulation downstream purification methods such as ultrafiltration and tangential flow filtration (TFF).* Knowledge of lipid chemistry and bioconjugation techniques.* Knowledge of cell-based assays for evaluating the performance and mechanism of action of novel delivery systems.* Familiarity with gel electrophoresis for nucleic acid and protein characterization.* Ability to work in a biosafety level 2 environment.* Experience in setting up and operating high-throughput screening protocols for delivery formulations.* Knowledge of formulation or assay automation, including lab automation equipment setup and programming.* Proven ability to independently interpret experimental data, troubleshoot technical challenges, and develop innovative solutions.* Excellent communication skills, with the ability to present complex scientific concepts clearly and concisely to diverse audiences.* A collaborative mindset and the ability to work effectively within a team-oriented environment.* Fluency in EnglishThe Evonik Group adopts an Equal Employment Opportunity (EEO) approach.
Candidates are assessed based on their educational qualifications, experience, job competencies and potential and shall not be discriminated against on the basis of race, ethnicity, age, gender, religion, nationality, disability or sexual orientation or other classifications protected by local, state, or provincial regulations.**您的申请**
为了确保尽快处理您的申请以及保护环境，请您通过我们的在线申请。作为雇主，您可以在找到有关赢创的更多信息。
请将您的申请发送给 Talent Acquisition Manager，说明您的最早入职日期和薪资期望。如有疑问或需要更多信息，可拨打Evonik Candidate Support 的电话：+49201 177 4200。**你的** **Talent Acquisition Manager:**Michelle Rush [第三方/短期员工]Company isEvonik Corporation #J-18808-Ljbffr
Cambridge, Massachusettstime type:
全职posted on:
今天发布job requisition id:
R35314**我们提供什么**与我们一起探索拥有无限可能性的世界。与我们一起展望未来，协助我们形成创新的解决方案，使我们的世界更具有可持续性，使生活更加健康，更加有活力以及更舒适。在赢创，您有机会与 33，000 名同事一起发展与成长。除了有吸引力的职业道路和高质量的发展方案以外，我们还通过 #SmartWork 提供基于绩效的薪酬、健康促进措施以及混合与灵活的工作模式。参与进来，发挥您的强项，开辟新天地，在我们这里找到适合您的工作。**在这儿您可以直接从我们的员工这里获悉更多关于赢创的信息：**We are looking for a passionate and innovative Scientist in the field of Nucleic Acid Delivery to join our dynamic team at the Cambridge Innovation Satellite, MA. This role focuses on advancing the development of lipid-based formulations for nucleic acid therapeutics. As part of a collaborative and interdisciplinary network of scientists, you will contribute to pioneering solutions that address significant challenges in medicine and ultimately improve patient outcomes.**RESPONSIBILITIES*** Design, develop, and characterize novel non-viral vectors for targeted delivery of nucleic acid-based therapeutics, including lipid nanoparticles and alternative gene delivery systems.* Conduct high-throughput in vitro experiments to evaluate the efficacy and safety of developed formulations in traditional and advanced cell culture models.* Collaborate with cross-functional teams to define project scopes, timelines, and deliverables based on market needs and internal capabilities.* Participate in the identification and evaluation of emerging technologies in nucleic acid delivery and contribute to the strategic direction of research initiatives.* Document research findings and present results to internal stakeholders and at scientific conferences, fostering a culture of innovation within the team.* Mentor junior scientists and technicians, providing guidance and support in their professional development.* Engage with external partners in academia and industry to enhance collaborative efforts and knowledge exchange.**REQUIREMENTS*** Ph.D. or 4+ years (M.Sc.) or 6+ years (B.Sc.) of relevant industry experience in LNP development and drug delivery with strong background in nucleic acid therapeutics and education in related discipline (Pharmaceutical Sciences, Biomedical Engineering, Biochemistry, etc).* Strong theoretical and practical knowledge of lipid-based and polymer-based delivery systems, manufacturing technologies and hands-on experience in nanoparticle characterization techniques (e.g., DLS, zeta potential, ribogreen, pKa, chromatography).* Knowledge of formulation downstream purification methods such as ultrafiltration and tangential flow filtration (TFF).* Knowledge of lipid chemistry and bioconjugation techniques.* Knowledge of cell-based assays for evaluating the performance and mechanism of action of novel delivery systems.* Familiarity with gel electrophoresis for nucleic acid and protein characterization.* Ability to work in a biosafety level 2 environment.* Experience in setting up and operating high-throughput screening protocols for delivery formulations.* Knowledge of formulation or assay automation, including lab automation equipment setup and programming.* Proven ability to independently interpret experimental data, troubleshoot technical challenges, and develop innovative solutions.* Excellent communication skills, with the ability to present complex scientific concepts clearly and concisely to diverse audiences.* A collaborative mindset and the ability to work effectively within a team-oriented environment.* Fluency in EnglishThe Evonik Group adopts an Equal Employment Opportunity (EEO) approach.
Candidates are assessed based on their educational qualifications, experience, job competencies and potential and shall not be discriminated against on the basis of race, ethnicity, age, gender, religion, nationality, disability or sexual orientation or other classifications protected by local, state, or provincial regulations.**您的申请**
为了确保尽快处理您的申请以及保护环境，请您通过我们的在线申请。作为雇主，您可以在找到有关赢创的更多信息。
请将您的申请发送给 Talent Acquisition Manager，说明您的最早入职日期和薪资期望。如有疑问或需要更多信息，可拨打Evonik Candidate Support 的电话：+49201 177 4200。**你的** **Talent Acquisition Manager:**Michelle Rush [第三方/短期员工]Company isEvonik Corporation #J-18808-Ljbffr