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The Role
Moderna's Bioanalytical and Molecular Assay team is looking for a Senior Research Associate with hands-on experience in the regulated GLP/GCP bioanalytical LC-MS/MS area. The individual should have recent experience in processing and analysis of a wide range of molecules such as lipids, biomarkers, proteins, and peptides. The role will support method development, validation, and sample analysis for clinical studies applying LC/MS techniques. The candidate must thrive in a scientifically stimulating, fast-paced environment with high expectations. Ability to troubleshoot, collaborate with cross-functional teams, respect for peers/colleagues, excellent work ethic, and setting the bar high are key values to thrive in our Team. Responsibilities
Develop, optimize, validate, and run bioanalytical LC/MS methods for quantitation of various types of molecules, particularly lipids, biomarkers, and proteins (peptides) Draft study plans, bioanalytical methods, and study reports Conduct bioanalytical assays following established protocols and SOPs, in compliance with GLP/GCP guidelines Coordinate with external CROs on method development, qualifications, and validations; review and approval SOWs, protocols, and reports Work closely with colleagues in Clinical Development as well as cross-functional groups Provide mass spectrometry support to scientists in Clinical Development, Platform, and other groups Stay abreast of literature, government guidelines, internal guidance on clinical trial conduct including GLP, GCP, internal SOPs and regulations and White Papers, as appropriate, for pre-clinical and clinical bioanalysis to ensure practices are consistent with regulatory expectations Qualifications
Bachelor’s degree with at least 5+ years laboratory experience or MS with 3+ years of demonstrated hands-on experience with the development and validation of bioanalytical methods using LC-MS Hands-on experience with sample preparation/extraction techniques for various analytes from biological matrices such as SPE, LLE, protein precipitation; CRO experience is a plus Ability to develop and implement methods for high throughput or (semi-)automated data analysis (e.g. Hamilton/Tecan automation) Experience with working with Electronic Lab Notebooks Willingness to learn new concepts and challenge boundaries; adaptability to change Organization and attention to detail; ability to handle multiple projects in a fast-paced environment Strong interpersonal skills with an eagerness to work with and support colleagues in other departments Proven ability to develop and work independently and to collaborate cross-functionally to accomplish goals in a timely manner Note: For this role, Moderna is currently unable to offer immigration sponsorship. Candidates must already hold work authorization in the US and be able to maintain that status without the need for future sponsorship. Benefits and Workplace Information
Best-in-class healthcare coverage, plus a suite of voluntary benefit programs A holistic approach to well-being, with access to fitness, mindfulness, and mental health support Lifestyle Spending Accounts to personalize well-being Family planning and adoption benefits Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown Savings and investment opportunities Location-specific perks and extras About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people drive scientific progress and shape our culture. We are proud to be recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. For more information, visit modernatx.com/careers. Working Model and Compliance
Moderna supports in-person collaboration with a 70/30 in-office work model. Moderna is a smoke-free, alcohol-free, and drug-free workplace. Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants. We welcome applicants regardless of race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other protected characteristic. Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accommodations
Moderna is committed to offering reasonable accommodations for qualified job applicants with disabilities. If you require an accommodation in the hiring process or to perform the essential functions of the position, please contact the Accommodations team at leavesandaccommodations@modernatx.com. Export Control Notice
This position may involve access to technology or data subject to U.S. export control laws. Employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Only individuals who qualify as U.S. persons are eligible for this position; Moderna cannot sponsor non-U.S. persons for export control licenses.
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Moderna's Bioanalytical and Molecular Assay team is looking for a Senior Research Associate with hands-on experience in the regulated GLP/GCP bioanalytical LC-MS/MS area. The individual should have recent experience in processing and analysis of a wide range of molecules such as lipids, biomarkers, proteins, and peptides. The role will support method development, validation, and sample analysis for clinical studies applying LC/MS techniques. The candidate must thrive in a scientifically stimulating, fast-paced environment with high expectations. Ability to troubleshoot, collaborate with cross-functional teams, respect for peers/colleagues, excellent work ethic, and setting the bar high are key values to thrive in our Team. Responsibilities
Develop, optimize, validate, and run bioanalytical LC/MS methods for quantitation of various types of molecules, particularly lipids, biomarkers, and proteins (peptides) Draft study plans, bioanalytical methods, and study reports Conduct bioanalytical assays following established protocols and SOPs, in compliance with GLP/GCP guidelines Coordinate with external CROs on method development, qualifications, and validations; review and approval SOWs, protocols, and reports Work closely with colleagues in Clinical Development as well as cross-functional groups Provide mass spectrometry support to scientists in Clinical Development, Platform, and other groups Stay abreast of literature, government guidelines, internal guidance on clinical trial conduct including GLP, GCP, internal SOPs and regulations and White Papers, as appropriate, for pre-clinical and clinical bioanalysis to ensure practices are consistent with regulatory expectations Qualifications
Bachelor’s degree with at least 5+ years laboratory experience or MS with 3+ years of demonstrated hands-on experience with the development and validation of bioanalytical methods using LC-MS Hands-on experience with sample preparation/extraction techniques for various analytes from biological matrices such as SPE, LLE, protein precipitation; CRO experience is a plus Ability to develop and implement methods for high throughput or (semi-)automated data analysis (e.g. Hamilton/Tecan automation) Experience with working with Electronic Lab Notebooks Willingness to learn new concepts and challenge boundaries; adaptability to change Organization and attention to detail; ability to handle multiple projects in a fast-paced environment Strong interpersonal skills with an eagerness to work with and support colleagues in other departments Proven ability to develop and work independently and to collaborate cross-functionally to accomplish goals in a timely manner Note: For this role, Moderna is currently unable to offer immigration sponsorship. Candidates must already hold work authorization in the US and be able to maintain that status without the need for future sponsorship. Benefits and Workplace Information
Best-in-class healthcare coverage, plus a suite of voluntary benefit programs A holistic approach to well-being, with access to fitness, mindfulness, and mental health support Lifestyle Spending Accounts to personalize well-being Family planning and adoption benefits Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown Savings and investment opportunities Location-specific perks and extras About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people drive scientific progress and shape our culture. We are proud to be recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. For more information, visit modernatx.com/careers. Working Model and Compliance
Moderna supports in-person collaboration with a 70/30 in-office work model. Moderna is a smoke-free, alcohol-free, and drug-free workplace. Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants. We welcome applicants regardless of race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other protected characteristic. Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accommodations
Moderna is committed to offering reasonable accommodations for qualified job applicants with disabilities. If you require an accommodation in the hiring process or to perform the essential functions of the position, please contact the Accommodations team at leavesandaccommodations@modernatx.com. Export Control Notice
This position may involve access to technology or data subject to U.S. export control laws. Employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Only individuals who qualify as U.S. persons are eligible for this position; Moderna cannot sponsor non-U.S. persons for export control licenses.
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