EyeBio
Sr. Scientist, Chemical Biotechnologies - Enzyme Engineering (Onsite)
EyeBio, Rahway, New Jersey, us, 07065
Job Description
The Chemical Biotechnologies group within the Process Research & Development Enabling Technologies Department in Rahway, New Jersey is seeking a Senior Scientist to expand our capabilities to design and engineer proteins with novel functions. The mission of the group is to invent, develop, and implement biomolecules and biocatalytic processes to advance our company's pipeline and our impact on the scientific community. We view protein engineering as a key enabling technology in modern drug discovery and development. We leverage computational modeling, advanced automation, and high-throughput screening to engineer novel proteins. We are committed to developing new methodologies and technologies that enhance protein engineering and improve human health. The group collaborates broadly within our company, with academic leaders, and with industry partners to expand and accelerate the impact of protein engineering on human health.
In this role, the incumbent will contribute directly to the invention of novel proteins by guiding gene acquisition, designing and building high-quality DNA libraries, expressing large protein libraries, developing assays, and/or characterizing libraries using high-throughput screens and selections. As part of project teams, they will collaborate across groups to develop novel solutions that solve complex problems. To accelerate the development of novel proteins, the candidate will develop engineering strategies and new technologies, choose which engineered proteins to select as leads, and deliver biocatalysts with improved functions and properties to enable drug discovery and impact clinical supply and commercial manufacturing processes. They will give scientific presentations internally and externally, contribute to the overall strategy and direction of the group, and develop novel protein engineering technologies. The successful candidate will join a diverse group of innovative scientists that are driving the next revolution in bioengineering.
Minimum Requirements
PhD or Postdoctoral Education or B.S. degree with 5+ years of experience or M.S. degree with 4+ years of experience in Molecular Biology, Biochemistry, Bioengineering, Synthetic Biology or a related field.
Published field-impacting research in which the applicant participated in the conception, execution, analysis, and drafting of the research.
Broad experience and knowledge in biological engineering, protein design, and directed evolution.
Significant expertise in one of the following: molecular biology, biochemistry, biophysics, computational protein design, or metabolic engineering.
Demonstrated ability to work within a collaborative multi-disciplinary team environment.
Excellent communication and organizational skills.
Preferred Experience and Skills
Experience engineering one of the following: novel biocatalysts, biosynthetic pathways, and/or de novo proteins.
Experience with multiple strategies to create genetic diversity, in vivo and in vitro expression optimization, and/or multiple high-throughput screening or selection methods.
Familiarity with one or more of the following areas are highly desired: next-generation sequencing, computational protein design, machine learning, microfluidics, or automation.
Experience with reproducible data analysis, for example using Python or R.
Required Skills Adaptability, Analytical Method Development, Biodesign, Biological Engineering, Cell-Based Assays, Chemical Engineering, Chemical Processing, Chemical Proteomics, Chemical Synthesis, Chemometrics, Chromatography, Data-Driven Decision Making, Drug Discovery Process, Flow Cytometry, Genetic Engineering, Immunochemistry, Mass Spectrometry Based Proteomics, Microfluidics, Molecular Biology, Motivation Management, Next Generation Sequencing, Process Analytical Technology, Process Engineering.
Preferred Skills Current Employees apply. Current Contingent Workers apply.
Location & Employment Details Location: Rahway, New Jersey, USA
Employment Status: Regular
Relocation: Domestic
Visa Sponsorship: Yes
Travel Requirements: None
Flexible Work Arrangements: Not Applicable
Shift: 1st – Day
Valid Driving License: No
Hazardous Material(s): None
Salary & Benefits Salary range: $114,700.00 – $180,500.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision, healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.
Application Process You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.
Equal Employment Opportunity Statement We are an Equal Employment Opportunity Employer. We provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, veteran status, disability status, or other protected characteristics.
Additional Legal Notices U.S. Hybrid Work Model: Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday – Thursday, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance.
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance.
Job Posting End Date Job Posting End Date: 11/3/2025
#J-18808-Ljbffr
In this role, the incumbent will contribute directly to the invention of novel proteins by guiding gene acquisition, designing and building high-quality DNA libraries, expressing large protein libraries, developing assays, and/or characterizing libraries using high-throughput screens and selections. As part of project teams, they will collaborate across groups to develop novel solutions that solve complex problems. To accelerate the development of novel proteins, the candidate will develop engineering strategies and new technologies, choose which engineered proteins to select as leads, and deliver biocatalysts with improved functions and properties to enable drug discovery and impact clinical supply and commercial manufacturing processes. They will give scientific presentations internally and externally, contribute to the overall strategy and direction of the group, and develop novel protein engineering technologies. The successful candidate will join a diverse group of innovative scientists that are driving the next revolution in bioengineering.
Minimum Requirements
PhD or Postdoctoral Education or B.S. degree with 5+ years of experience or M.S. degree with 4+ years of experience in Molecular Biology, Biochemistry, Bioengineering, Synthetic Biology or a related field.
Published field-impacting research in which the applicant participated in the conception, execution, analysis, and drafting of the research.
Broad experience and knowledge in biological engineering, protein design, and directed evolution.
Significant expertise in one of the following: molecular biology, biochemistry, biophysics, computational protein design, or metabolic engineering.
Demonstrated ability to work within a collaborative multi-disciplinary team environment.
Excellent communication and organizational skills.
Preferred Experience and Skills
Experience engineering one of the following: novel biocatalysts, biosynthetic pathways, and/or de novo proteins.
Experience with multiple strategies to create genetic diversity, in vivo and in vitro expression optimization, and/or multiple high-throughput screening or selection methods.
Familiarity with one or more of the following areas are highly desired: next-generation sequencing, computational protein design, machine learning, microfluidics, or automation.
Experience with reproducible data analysis, for example using Python or R.
Required Skills Adaptability, Analytical Method Development, Biodesign, Biological Engineering, Cell-Based Assays, Chemical Engineering, Chemical Processing, Chemical Proteomics, Chemical Synthesis, Chemometrics, Chromatography, Data-Driven Decision Making, Drug Discovery Process, Flow Cytometry, Genetic Engineering, Immunochemistry, Mass Spectrometry Based Proteomics, Microfluidics, Molecular Biology, Motivation Management, Next Generation Sequencing, Process Analytical Technology, Process Engineering.
Preferred Skills Current Employees apply. Current Contingent Workers apply.
Location & Employment Details Location: Rahway, New Jersey, USA
Employment Status: Regular
Relocation: Domestic
Visa Sponsorship: Yes
Travel Requirements: None
Flexible Work Arrangements: Not Applicable
Shift: 1st – Day
Valid Driving License: No
Hazardous Material(s): None
Salary & Benefits Salary range: $114,700.00 – $180,500.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision, healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.
Application Process You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.
Equal Employment Opportunity Statement We are an Equal Employment Opportunity Employer. We provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, veteran status, disability status, or other protected characteristics.
Additional Legal Notices U.S. Hybrid Work Model: Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday – Thursday, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance.
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance.
Job Posting End Date Job Posting End Date: 11/3/2025
#J-18808-Ljbffr