BioSpace
Overview
Process Development Sr Scientist role at BioSpace – join Amgen’s mission of serving patients. This role contributes to early formulation development and physicochemical characterization with a focus on chemical stability to advance preclinical and clinical development programs. You will support regulatory filings and Amgen’s intellectual property and may participate with Discovery Research and Early Development teams as needed.
What You Will Do
Evaluate drug candidate stability, structural elucidation, and identify degradation pathways.
Assess synthetic molecules (developability) and provide preclinical formulation support.
Support lead optimization and form selection to meet the target product profile.
Apply in silico and in vitro models to support molecule and biopharmaceutical assessments and identify development strategies.
Coordinate with team members and external partners to meet tasks and milestones.
Assist the project team lead in authoring technical reports and CMC sections in regulatory documents.
Apply continuous improvement practices to enhance laboratory efficiency.
What We Expect Of You We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is a collaborative individual with these qualifications.
Basic Qualifications
Bachelor’s degree with 5+ years of scientific experience OR
Master’s degree with 3+ years of scientific experience OR
Doctorate (PhD) or PharmD or MD with relevant post-doc where applicable
Preferred Qualifications
Doctorate (PhD or PharmD) with 2+ years post-PhD in Pharmaceutics, Pharmacy, Chemistry or related field
Experience in synthetic, mechanistic, or physical organic chemistry and structural elucidation
Strong understanding of Mass Spectrometry or LC-MS
Experience in preformulation techniques including HPLC analysis and physicochemical evaluation with solid-state characterization
Experience in chemical kinetics, pharmacokinetics or biopharmaceutical modeling
Ability to take initiative, work independently, and be flexible
Experience in liquid dosage forms for synthetics
Ability to integrate automation and data science approaches to enhance workflows
Proficiency with instrumentation platforms and data management systems
Experience applying statistical analysis and data visualization tools
Strong problem-solving, collaboration, and cross-functional skills
Excellent written, verbal, and presentation skills
What You Can Expect From Us We support your professional and personal growth and well-being with competitive benefits and a collaborative culture. The salary range is posted and may vary based on skills, experience, and qualifications. Amgen offers a Total Rewards Plan including health and welfare plans, retirement savings, work/life balance, and career development opportunities.
Retirement and Savings Plan with company contributions
Comprehensive medical, dental, and vision coverage
Life and disability insurance and flexible spending accounts
Discretionary annual bonus or sales-based incentive, for applicable roles
Stock-based long-term incentives
Awards for time-off and flexible work models where possible
Amgen is an Equal Opportunity employer and will consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by law. We will provide reasonable accommodations to applicants with disabilities upon request.
Apply now and make a lasting impact with the Amgen team.
careers.amgen.com
#J-18808-Ljbffr
What You Will Do
Evaluate drug candidate stability, structural elucidation, and identify degradation pathways.
Assess synthetic molecules (developability) and provide preclinical formulation support.
Support lead optimization and form selection to meet the target product profile.
Apply in silico and in vitro models to support molecule and biopharmaceutical assessments and identify development strategies.
Coordinate with team members and external partners to meet tasks and milestones.
Assist the project team lead in authoring technical reports and CMC sections in regulatory documents.
Apply continuous improvement practices to enhance laboratory efficiency.
What We Expect Of You We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is a collaborative individual with these qualifications.
Basic Qualifications
Bachelor’s degree with 5+ years of scientific experience OR
Master’s degree with 3+ years of scientific experience OR
Doctorate (PhD) or PharmD or MD with relevant post-doc where applicable
Preferred Qualifications
Doctorate (PhD or PharmD) with 2+ years post-PhD in Pharmaceutics, Pharmacy, Chemistry or related field
Experience in synthetic, mechanistic, or physical organic chemistry and structural elucidation
Strong understanding of Mass Spectrometry or LC-MS
Experience in preformulation techniques including HPLC analysis and physicochemical evaluation with solid-state characterization
Experience in chemical kinetics, pharmacokinetics or biopharmaceutical modeling
Ability to take initiative, work independently, and be flexible
Experience in liquid dosage forms for synthetics
Ability to integrate automation and data science approaches to enhance workflows
Proficiency with instrumentation platforms and data management systems
Experience applying statistical analysis and data visualization tools
Strong problem-solving, collaboration, and cross-functional skills
Excellent written, verbal, and presentation skills
What You Can Expect From Us We support your professional and personal growth and well-being with competitive benefits and a collaborative culture. The salary range is posted and may vary based on skills, experience, and qualifications. Amgen offers a Total Rewards Plan including health and welfare plans, retirement savings, work/life balance, and career development opportunities.
Retirement and Savings Plan with company contributions
Comprehensive medical, dental, and vision coverage
Life and disability insurance and flexible spending accounts
Discretionary annual bonus or sales-based incentive, for applicable roles
Stock-based long-term incentives
Awards for time-off and flexible work models where possible
Amgen is an Equal Opportunity employer and will consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by law. We will provide reasonable accommodations to applicants with disabilities upon request.
Apply now and make a lasting impact with the Amgen team.
careers.amgen.com
#J-18808-Ljbffr