BioSpace
Overview
Join Amgen's mission of serving patients. Our work focuses on Oncology, Inflammation, General Medicine, and Rare Disease to research, manufacture, and deliver innovative medicines that help people live longer, fuller lives.
What You Will Do We are seeking a highly skilled organic chemist to join the oligonucleotide delivery team and develop the next generation of RNA therapeutics. The Synthetic Chemist will design and prepare novel delivery ligands, conjugation linkers, and nucleotides to chemically modify oligonucleotides for enhanced delivery and efficacy. The ideal candidate will have a diverse organic chemistry skillset with experience in small molecule and carbohydrate synthesis and will collaborate with oligonucleotide chemists, conjugation chemists, protein chemists, and biologists to explore novel delivery mechanisms and contribute to our therapeutic RNA pipeline.
Responsibilities
Design and synthesize small molecules and carbohydrate-based constructs for oligonucleotide delivery.
Prepare delivery ligands, conjugation linkers, and modified nucleotides to enhance delivery and efficacy.
Collaborate with cross-functional teams to advance the therapeutic RNA pipeline.
Basic Qualifications
Doctorate degree (PhD) OR PharmD OR MD, or
Masters degree with 3 years of relevant experience
Bachelors degree with 5 years of relevant experience
Preferred Qualifications
Ph.D. in synthetic organic chemistry or related discipline with postdoctoral experience or >2 years industry experience in small molecule or carbohydrate synthesis.
Hands-on laboratory experience preparing a diverse range of synthetic compounds.
Ability to collaborate with oligonucleotide chemists, conjugation chemists, and biologists to design molecules that modify oligonucleotides.
Experience with state-of-the-art techniques and characterization of synthetic molecules; strong communication and teamwork skills in a dynamic environment.
What You Can Expect From Us We support your professional and personal growth, with competitive benefits and a collaborative culture. The salary range will vary based on skills, experience, and qualifications.
Comprehensive employee benefits package including retirement and savings plan, medical, dental, vision, life and disability insurance, and flexible spending accounts
Discretionary annual bonus program; field sales incentive plan where applicable
Stock-based long-term incentives and award-winning time-off plans
Flexible work models where possible
Amgen is an Equal Opportunity employer and will consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will provide reasonable accommodation in the application or interview process as needed.
Application deadline: Amgen does not have a firm deadline and will continue accepting applications until a suitable candidate is selected.
#J-18808-Ljbffr
What You Will Do We are seeking a highly skilled organic chemist to join the oligonucleotide delivery team and develop the next generation of RNA therapeutics. The Synthetic Chemist will design and prepare novel delivery ligands, conjugation linkers, and nucleotides to chemically modify oligonucleotides for enhanced delivery and efficacy. The ideal candidate will have a diverse organic chemistry skillset with experience in small molecule and carbohydrate synthesis and will collaborate with oligonucleotide chemists, conjugation chemists, protein chemists, and biologists to explore novel delivery mechanisms and contribute to our therapeutic RNA pipeline.
Responsibilities
Design and synthesize small molecules and carbohydrate-based constructs for oligonucleotide delivery.
Prepare delivery ligands, conjugation linkers, and modified nucleotides to enhance delivery and efficacy.
Collaborate with cross-functional teams to advance the therapeutic RNA pipeline.
Basic Qualifications
Doctorate degree (PhD) OR PharmD OR MD, or
Masters degree with 3 years of relevant experience
Bachelors degree with 5 years of relevant experience
Preferred Qualifications
Ph.D. in synthetic organic chemistry or related discipline with postdoctoral experience or >2 years industry experience in small molecule or carbohydrate synthesis.
Hands-on laboratory experience preparing a diverse range of synthetic compounds.
Ability to collaborate with oligonucleotide chemists, conjugation chemists, and biologists to design molecules that modify oligonucleotides.
Experience with state-of-the-art techniques and characterization of synthetic molecules; strong communication and teamwork skills in a dynamic environment.
What You Can Expect From Us We support your professional and personal growth, with competitive benefits and a collaborative culture. The salary range will vary based on skills, experience, and qualifications.
Comprehensive employee benefits package including retirement and savings plan, medical, dental, vision, life and disability insurance, and flexible spending accounts
Discretionary annual bonus program; field sales incentive plan where applicable
Stock-based long-term incentives and award-winning time-off plans
Flexible work models where possible
Amgen is an Equal Opportunity employer and will consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will provide reasonable accommodation in the application or interview process as needed.
Application deadline: Amgen does not have a firm deadline and will continue accepting applications until a suitable candidate is selected.
#J-18808-Ljbffr