Eli Lilly and Company
Process Analytical Technologies Scientist
Eli Lilly and Company, Lebanon, Indiana, United States, 46052
Process Analytical Technologies Scientist
Join to apply for the
Process Analytical Technologies Scientist
role at
Eli Lilly and Company .
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees work to discover and bring life‑changing medicines, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We put people first and are looking for people who are determined to make life better for people worldwide.
Organization and Position Overview Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first‑ever facility of its kind, combining research and manufacturing in a single location, will allow Lilly to further develop innovative solutions to optimize manufacturing processes, increase capacity for clinical trial medicines, and reduce costs and environmental impact.
In the Project Delivery Phase and Startup Phase of the project (2025‑2028), roles will be fluid and dynamic as we support project delivery, build a new organization, and develop the necessary systems and business processes required to support GMP operations. This will require significant collaboration, creativity, and resilience as the Lilly Medicine Foundry goes from design, to start‑up, and to steady‑state operations.
The Process Analytical Technology (PAT) Scientist role, a technical‑track position, seeks a collaborative, inclusive, and energetic scientist who will participate in the installation and execution of PAT strategies at the Lilly Medicine Foundry to support the production of synthetic and biologic drug substance processes. This role will collaborate with the parent CMC development organizations to understand the needs of the portfolio and PAT to be implemented in production. The site will utilize the latest automation to further analytical capabilities, including online in‑process control testing through material release and ongoing process monitoring at the site. The PAT group will focus on the implementation of new technologies and analytical process improvements. This position involves working cross‑functionally within the site and across the network to develop strategic functional capabilities and will ensure appropriate capacity, capabilities, and business processes are developed, implemented, and sustained to deliver the required information to the project teams. This position will be key to ensuring a strong safety culture and establishing a safety, quality, and continuous improvement focused mindset within the organization.
Responsibilities
Drive implementation of technical solutions and analytical strategies via PAT to enable drug substance production at the Lilly Medicine Foundry.
Investigate the feasibility of instruments to use for in‑line monitoring. Ensure methods are technically sound, well‑developed, and fit‑for‑purpose.
Demonstrate high learning agility and the ability to understand and exploit effective scientific concepts and methods across multiple subject areas (e.g., chemistry, PAT, and modeling and simulation).
Support automation development (e.g., integrated control systems) between PAT tools and process data systems (e.g., synTQ or other systems).
Plan and manage short‑term and long‑term development activities. Develop and/or review technical agendas and timelines for project work. Recommend resource allocation to accomplish projects according to plans, communicate progress, and propose changes in timeline, objectives, or direction.
Collaborate closely with organizations across development and manufacturing to deliver material and information for clinical trials and regulatory submissions.
Welcome varied perspectives to create new solutions.
Coordinate instrumentation between different projects to allow equal usage of available tools for project‑specific needs.
Author or contribute to technical documents including SOPs, technology transfer documents, process flow diagrams, regulatory submissions, patents, and scientific papers.
Ensure work and team activities are aligned with all relevant development quality, regulatory, HSE, GLP, and GMP requirements.
Basic Requirements
B.S. in chemistry, chemical engineering, or related field.
Background in chemometrics/PAT with a strong focus on application.
Fundamental knowledge of cGMP compliance requirements and cGMP experience.
Additional Preferences
Experience with product development, including technical transfer of analytical methods into manufacturing operations.
Demonstrated ability to drive and accept change.
Good in …
EEO Statement Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities. If you require accommodation to submit a resume, please complete the accommodation request form listed on the Lilly careers site. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Compensation and Benefits Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $65,250 – $169,400. Full‑time employees are also eligible for a company bonus, and Lilly offers a comprehensive benefits program, including 401(k) participation, pension, vacation benefits, medical, dental, vision, prescription drug benefits, flexible benefits, life and death insurance, and wellness programs.
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Process Analytical Technologies Scientist
role at
Eli Lilly and Company .
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees work to discover and bring life‑changing medicines, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We put people first and are looking for people who are determined to make life better for people worldwide.
Organization and Position Overview Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first‑ever facility of its kind, combining research and manufacturing in a single location, will allow Lilly to further develop innovative solutions to optimize manufacturing processes, increase capacity for clinical trial medicines, and reduce costs and environmental impact.
In the Project Delivery Phase and Startup Phase of the project (2025‑2028), roles will be fluid and dynamic as we support project delivery, build a new organization, and develop the necessary systems and business processes required to support GMP operations. This will require significant collaboration, creativity, and resilience as the Lilly Medicine Foundry goes from design, to start‑up, and to steady‑state operations.
The Process Analytical Technology (PAT) Scientist role, a technical‑track position, seeks a collaborative, inclusive, and energetic scientist who will participate in the installation and execution of PAT strategies at the Lilly Medicine Foundry to support the production of synthetic and biologic drug substance processes. This role will collaborate with the parent CMC development organizations to understand the needs of the portfolio and PAT to be implemented in production. The site will utilize the latest automation to further analytical capabilities, including online in‑process control testing through material release and ongoing process monitoring at the site. The PAT group will focus on the implementation of new technologies and analytical process improvements. This position involves working cross‑functionally within the site and across the network to develop strategic functional capabilities and will ensure appropriate capacity, capabilities, and business processes are developed, implemented, and sustained to deliver the required information to the project teams. This position will be key to ensuring a strong safety culture and establishing a safety, quality, and continuous improvement focused mindset within the organization.
Responsibilities
Drive implementation of technical solutions and analytical strategies via PAT to enable drug substance production at the Lilly Medicine Foundry.
Investigate the feasibility of instruments to use for in‑line monitoring. Ensure methods are technically sound, well‑developed, and fit‑for‑purpose.
Demonstrate high learning agility and the ability to understand and exploit effective scientific concepts and methods across multiple subject areas (e.g., chemistry, PAT, and modeling and simulation).
Support automation development (e.g., integrated control systems) between PAT tools and process data systems (e.g., synTQ or other systems).
Plan and manage short‑term and long‑term development activities. Develop and/or review technical agendas and timelines for project work. Recommend resource allocation to accomplish projects according to plans, communicate progress, and propose changes in timeline, objectives, or direction.
Collaborate closely with organizations across development and manufacturing to deliver material and information for clinical trials and regulatory submissions.
Welcome varied perspectives to create new solutions.
Coordinate instrumentation between different projects to allow equal usage of available tools for project‑specific needs.
Author or contribute to technical documents including SOPs, technology transfer documents, process flow diagrams, regulatory submissions, patents, and scientific papers.
Ensure work and team activities are aligned with all relevant development quality, regulatory, HSE, GLP, and GMP requirements.
Basic Requirements
B.S. in chemistry, chemical engineering, or related field.
Background in chemometrics/PAT with a strong focus on application.
Fundamental knowledge of cGMP compliance requirements and cGMP experience.
Additional Preferences
Experience with product development, including technical transfer of analytical methods into manufacturing operations.
Demonstrated ability to drive and accept change.
Good in …
EEO Statement Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities. If you require accommodation to submit a resume, please complete the accommodation request form listed on the Lilly careers site. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Compensation and Benefits Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $65,250 – $169,400. Full‑time employees are also eligible for a company bonus, and Lilly offers a comprehensive benefits program, including 401(k) participation, pension, vacation benefits, medical, dental, vision, prescription drug benefits, flexible benefits, life and death insurance, and wellness programs.
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