BioSpace
Company Overview
Dyne Therapeutics focuses on delivering functional improvement for people living with genetically driven neuromuscular diseases. The company develops therapeutics targeting muscle and the central nervous system (CNS) to address the root cause of disease. Clinical programs are advanced for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. Dyne is on a mission to deliver functional improvement for individuals, families, and communities.
Role Summary The Director of Trade and Distribution will bring extensive market access experience to our first product launches in neuromuscular disease. The focus will be on launch readiness and commercialization of our lead assets in Duchenne Muscular Dystrophy and DM1. This role manages and executes distribution and channel strategy across pre‑launch, launch, and post‑launch phases, implementing and managing all contracts with 3PL, specialty distributors, specialty pharmacies, and other channels.
Key responsibilities include collaborating with finance, legal, marketing, sales, market access, patient services, commercial operations, analytics, quality, and supply chain to ensure efficient and seamless access to patients. The incumbent will also support a high‑performing team, collaborating cross‑functionally to deliver a unified Go‑to‑Market strategy.
Primary Responsibilities
Develop, lead, and implement the trade and distribution strategy.
Partner with the payer team to ensure the distribution channel strategy aligns with payer expectations.
Execute strategy and operationalize 3PL, wholesalers/specialty distributors, and specialty pharmacies to ensure product availability.
Collaborate with legal, finance, and other internal functions to draft, execute, and implement innovative, compliant contracts with key partners.
Monitor service agreements to ensure compliance and hold partners accountable.
Partner with patient support, marketing, commercial analytics, and sales to continually monitor and evolve the distribution strategy.
Identify, develop, and execute on compliance, adherence, and other patient support programs using distribution partners.
Lead and manage channel engagement across all stakeholders, including 3PL, specialty distribution, and specialty pharmacy/infusion providers.
Ensure proper purchasing, stocking, and inventory to achieve corporate goals in a compliant manner.
Develop and implement performance metrics, dashboards and communicate results internally.
Partner with patient support, managed markets, finance, and supply chain to develop an appropriate return goods policy and ensure compliance.
Spearhead an infusion center/site of care distribution strategy.
Work cross‑functionally with manufacturing/supply chain and quality teams on chain‑of‑custody and inventory tracking.
Perform trade data reporting and network performance assessments with commercial analytics.
Prepare and conduct quarterly business reviews with trade partners.
Lead state licensing initiatives.
Lead budget and vendor management to ensure timely and fiscally responsible project execution.
Support commercial input into CMC supply chain strategy and planning.
Education, Knowledge & Skill Requirements
BA/BS degree required; advanced degree (MBA, PhD, PharmD) preferred.
12+ years of bio/pharmaceutical experience with an understanding of US distribution models.
8+ years of US channel management experience (3PL, specialty distribution, specialty pharmacy).
Previous rare disease experience and Buy‑and‑Bill models, including infusion products, preferred.
Experience partnering with specialty pharmacies to establish fee‑for‑service programs.
Strong understanding of policies, regulations, and compliance issues surrounding trade and distribution.
Demonstrated skills in business planning, distribution strategy, problem‑solving, negotiation, and financial acumen.
Experience with new product launch.
Influential, clear communicator able to simplify complex issues to broad audiences.
Enterprise mindset that brings company values to everyday activities.
Ability to operate in a start‑up environment while maintaining solution‑oriented mentality.
Willingness to travel as required.
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
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Role Summary The Director of Trade and Distribution will bring extensive market access experience to our first product launches in neuromuscular disease. The focus will be on launch readiness and commercialization of our lead assets in Duchenne Muscular Dystrophy and DM1. This role manages and executes distribution and channel strategy across pre‑launch, launch, and post‑launch phases, implementing and managing all contracts with 3PL, specialty distributors, specialty pharmacies, and other channels.
Key responsibilities include collaborating with finance, legal, marketing, sales, market access, patient services, commercial operations, analytics, quality, and supply chain to ensure efficient and seamless access to patients. The incumbent will also support a high‑performing team, collaborating cross‑functionally to deliver a unified Go‑to‑Market strategy.
Primary Responsibilities
Develop, lead, and implement the trade and distribution strategy.
Partner with the payer team to ensure the distribution channel strategy aligns with payer expectations.
Execute strategy and operationalize 3PL, wholesalers/specialty distributors, and specialty pharmacies to ensure product availability.
Collaborate with legal, finance, and other internal functions to draft, execute, and implement innovative, compliant contracts with key partners.
Monitor service agreements to ensure compliance and hold partners accountable.
Partner with patient support, marketing, commercial analytics, and sales to continually monitor and evolve the distribution strategy.
Identify, develop, and execute on compliance, adherence, and other patient support programs using distribution partners.
Lead and manage channel engagement across all stakeholders, including 3PL, specialty distribution, and specialty pharmacy/infusion providers.
Ensure proper purchasing, stocking, and inventory to achieve corporate goals in a compliant manner.
Develop and implement performance metrics, dashboards and communicate results internally.
Partner with patient support, managed markets, finance, and supply chain to develop an appropriate return goods policy and ensure compliance.
Spearhead an infusion center/site of care distribution strategy.
Work cross‑functionally with manufacturing/supply chain and quality teams on chain‑of‑custody and inventory tracking.
Perform trade data reporting and network performance assessments with commercial analytics.
Prepare and conduct quarterly business reviews with trade partners.
Lead state licensing initiatives.
Lead budget and vendor management to ensure timely and fiscally responsible project execution.
Support commercial input into CMC supply chain strategy and planning.
Education, Knowledge & Skill Requirements
BA/BS degree required; advanced degree (MBA, PhD, PharmD) preferred.
12+ years of bio/pharmaceutical experience with an understanding of US distribution models.
8+ years of US channel management experience (3PL, specialty distribution, specialty pharmacy).
Previous rare disease experience and Buy‑and‑Bill models, including infusion products, preferred.
Experience partnering with specialty pharmacies to establish fee‑for‑service programs.
Strong understanding of policies, regulations, and compliance issues surrounding trade and distribution.
Demonstrated skills in business planning, distribution strategy, problem‑solving, negotiation, and financial acumen.
Experience with new product launch.
Influential, clear communicator able to simplify complex issues to broad audiences.
Enterprise mindset that brings company values to everyday activities.
Ability to operate in a start‑up environment while maintaining solution‑oriented mentality.
Willingness to travel as required.
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
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