Neurocrine Biosciences
Associate Scientist, Translational Biology
Neurocrine Biosciences, San Diego, California, United States, 92189
Overview
At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs. Neurocrine Biosciences is a leading neuroscience-focused biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company\'s diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington\'s disease, classic congenital adrenal hyperplasia, endometriosis and uterine fibroids, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit Neurocrine Biosciences website, and follow the company on LinkedIn, X and Facebook. (in collaboration with AbbVie) About the Role
This is a hands-on role to execute in vivo experiments in genetic, behavioral, and pharmacological rodent models to evaluate novel treatments for psychiatric, neurological, and neurodegenerative disorders. Within a dynamic and engaging environment, you will interact with scientific investigators to plan and execute preclinical rodent studies. Strong technical skills, attention to detail, and excellent communication ability are required. The primary tasks for this position will include compound formulation and dosing, behavioral assessments, and tissue collection. Your Contributions
Execute on rodent in vivo experiments: animal handling, test article dosing via various administration routes (PO, IP, SC, IV), behavioral monitoring, data collection, as well as data interpretation/analysis
Perform rodent perfusion, microwave, necropsy, dissections and tissue collection
Assist with identifying new behavioral assays/models
Behavioral assay development, validation, and screening
Rodent stereotaxic surgery
Perform plate reader-based wet lab analysis using a range of tools (i.e. Luminex)
Provide maintenance and training to others for various lab equipment
Coordinate externally run studies with academic and industry-based partners
Present data at internal group/team meetings
Work collaboratively with colleagues and teammates from multi-disciplinary project teams
Efficiently managing scheduling of studies, and managing own time to complete assigned work by due dates
Maintain accurate databases and experimental notebooks of results
Assisting in other related procedures as assigned by the supervisor
Statistical analysis and reporting of data
Handle and dose animals in a laboratory setting
Other duties as assigned
Requirements
BS/BA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some experience with handling and dosing animals in a laboratory setting OR
MS/MA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some experience with handling and dosing animals in a laboratory setting
Previous experience with rodent preclinical assays of psychotic disorders, cognitive disorders, and depression is preferred
Experience handling mice and rats and general familiarity with behavioral analysis, including automated techniques
Experience with in vivo pharmacology and efficacy studies including multiple dosing routes of administration and necropsy procedures
Experience maintaining various types of lab equipment and providing training to team members
Can independently manage and troubleshoot rodent studies for in vivo endpoints
Proficient in Microsoft Office (Outlook, Excel, PowerPoint), as well as some basic graphical and/or statistical software (e.g., Prism, Spotfire, JMP, etc.)
Experience with small animal survival surgery, stereotaxic brain injections, and in vivo models of neuropsychiatric/neurodegenerative disease a plus
Superior attention to detail, punctual, flexible, and an outstanding team-player who is comfortable working on and prioritizing multiple projects
Able to execute experiments efficiently and suggest small process improvements
Able to recognize patterns or inconsistencies in data results
Able to deduce meaningful results while conducting routine analyses or troubleshoot minor issues. Good knowledge of one scientific discipline
Able to review primary literature and synthesize summaries
Developing knowledge of scientific principles, methods and techniques
Good knowledge and some experience working with discipline specific laboratory equipment/tools
Good computer skills
Developing communications, problem-solving, analytical thinking, planning and organization skills
Understands importance of meeting deadlines
High level of organization and attention to detail
Willingness and ability to work both independently and as part of a team
Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description. The hourly rate we reasonably expect to pay is $34.66-$48.98. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 15% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.
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At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs. Neurocrine Biosciences is a leading neuroscience-focused biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company\'s diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington\'s disease, classic congenital adrenal hyperplasia, endometriosis and uterine fibroids, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit Neurocrine Biosciences website, and follow the company on LinkedIn, X and Facebook. (in collaboration with AbbVie) About the Role
This is a hands-on role to execute in vivo experiments in genetic, behavioral, and pharmacological rodent models to evaluate novel treatments for psychiatric, neurological, and neurodegenerative disorders. Within a dynamic and engaging environment, you will interact with scientific investigators to plan and execute preclinical rodent studies. Strong technical skills, attention to detail, and excellent communication ability are required. The primary tasks for this position will include compound formulation and dosing, behavioral assessments, and tissue collection. Your Contributions
Execute on rodent in vivo experiments: animal handling, test article dosing via various administration routes (PO, IP, SC, IV), behavioral monitoring, data collection, as well as data interpretation/analysis
Perform rodent perfusion, microwave, necropsy, dissections and tissue collection
Assist with identifying new behavioral assays/models
Behavioral assay development, validation, and screening
Rodent stereotaxic surgery
Perform plate reader-based wet lab analysis using a range of tools (i.e. Luminex)
Provide maintenance and training to others for various lab equipment
Coordinate externally run studies with academic and industry-based partners
Present data at internal group/team meetings
Work collaboratively with colleagues and teammates from multi-disciplinary project teams
Efficiently managing scheduling of studies, and managing own time to complete assigned work by due dates
Maintain accurate databases and experimental notebooks of results
Assisting in other related procedures as assigned by the supervisor
Statistical analysis and reporting of data
Handle and dose animals in a laboratory setting
Other duties as assigned
Requirements
BS/BA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some experience with handling and dosing animals in a laboratory setting OR
MS/MA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some experience with handling and dosing animals in a laboratory setting
Previous experience with rodent preclinical assays of psychotic disorders, cognitive disorders, and depression is preferred
Experience handling mice and rats and general familiarity with behavioral analysis, including automated techniques
Experience with in vivo pharmacology and efficacy studies including multiple dosing routes of administration and necropsy procedures
Experience maintaining various types of lab equipment and providing training to team members
Can independently manage and troubleshoot rodent studies for in vivo endpoints
Proficient in Microsoft Office (Outlook, Excel, PowerPoint), as well as some basic graphical and/or statistical software (e.g., Prism, Spotfire, JMP, etc.)
Experience with small animal survival surgery, stereotaxic brain injections, and in vivo models of neuropsychiatric/neurodegenerative disease a plus
Superior attention to detail, punctual, flexible, and an outstanding team-player who is comfortable working on and prioritizing multiple projects
Able to execute experiments efficiently and suggest small process improvements
Able to recognize patterns or inconsistencies in data results
Able to deduce meaningful results while conducting routine analyses or troubleshoot minor issues. Good knowledge of one scientific discipline
Able to review primary literature and synthesize summaries
Developing knowledge of scientific principles, methods and techniques
Good knowledge and some experience working with discipline specific laboratory equipment/tools
Good computer skills
Developing communications, problem-solving, analytical thinking, planning and organization skills
Understands importance of meeting deadlines
High level of organization and attention to detail
Willingness and ability to work both independently and as part of a team
Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description. The hourly rate we reasonably expect to pay is $34.66-$48.98. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 15% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.
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