The Fountain Group
Scientist III (Analytical Characterization)
The Fountain Group, Worcester, Massachusetts, us, 01609
Details
Location: Worcester, MA – 100% onsite Rate: $60-70 an hour 12 month contract to start with the possibility of extension or conversion depending on performance and business needs. Job Description
As a Scientist, you will be part of the Analytical Characterization Group (ACG) within the Analytical Development Department. ACG focuses on providing routine, investigative, and in-depth characterization analyses of Client's biologics to support product and process development for early-phase, late-phase, and commercial programs using liquid chromatography mass spectrometry (LC-MS), spectroscopy and various other biophysical assays. The successful candidate will contribute to the development and performance of analytical assays and will contribute to the continuous improvement and innovation within ACG and the Analytical Development Department. Perform mass spectrometry analyses (i.e., intact/reduced mass analysis by LC-MS and peptide mapping by LC-MS) of Client's biologics to provide sequence verification and post-translational modification profiles. Independently perform separation methods (e.g., fractionation & analysis of variants) using HPLC and AKTA Perform biophysical methods (e.g., DSC) of Client's biologics to support characterization studies. Design and execute experiments for method development and/or investigations. Support process development by performing raw material analysis using vibrational spectroscopy and executing metabolomics experiments using mass spectrometry. Generate and communicate precise, reliable, and reproducible data in a timely manner. Organize and document experiments and results in an electronic laboratory notebook. Draft protocols, method development reports, and technical characterization reports. Required Skills
Bachelors or Masters in chemistry, biology, biochemistry or related technical discipline with typically 5+ (BS) or 2+ (MS) years of relevant experience in biotech/pharmaceutical industry setting. Must have experience performing separation assays such as HPLC/UPLC chromatography Must have experience performing Perform fractionation using AKTA Must have experience performing LC-MS experiments on intact proteins Knowledge of vibrational spectroscopy (e.g., IR, NIR and Raman) and multivariate analysis is desirable.
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Location: Worcester, MA – 100% onsite Rate: $60-70 an hour 12 month contract to start with the possibility of extension or conversion depending on performance and business needs. Job Description
As a Scientist, you will be part of the Analytical Characterization Group (ACG) within the Analytical Development Department. ACG focuses on providing routine, investigative, and in-depth characterization analyses of Client's biologics to support product and process development for early-phase, late-phase, and commercial programs using liquid chromatography mass spectrometry (LC-MS), spectroscopy and various other biophysical assays. The successful candidate will contribute to the development and performance of analytical assays and will contribute to the continuous improvement and innovation within ACG and the Analytical Development Department. Perform mass spectrometry analyses (i.e., intact/reduced mass analysis by LC-MS and peptide mapping by LC-MS) of Client's biologics to provide sequence verification and post-translational modification profiles. Independently perform separation methods (e.g., fractionation & analysis of variants) using HPLC and AKTA Perform biophysical methods (e.g., DSC) of Client's biologics to support characterization studies. Design and execute experiments for method development and/or investigations. Support process development by performing raw material analysis using vibrational spectroscopy and executing metabolomics experiments using mass spectrometry. Generate and communicate precise, reliable, and reproducible data in a timely manner. Organize and document experiments and results in an electronic laboratory notebook. Draft protocols, method development reports, and technical characterization reports. Required Skills
Bachelors or Masters in chemistry, biology, biochemistry or related technical discipline with typically 5+ (BS) or 2+ (MS) years of relevant experience in biotech/pharmaceutical industry setting. Must have experience performing separation assays such as HPLC/UPLC chromatography Must have experience performing Perform fractionation using AKTA Must have experience performing LC-MS experiments on intact proteins Knowledge of vibrational spectroscopy (e.g., IR, NIR and Raman) and multivariate analysis is desirable.
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